Abstract
Although mixed infections are known to be clinically relevant in conditions such as nosocomial pneumonia and ventilator-related pneumonia, it is increasingly recognized that a substantial number of community-acquired lower respiratory tract infections may also be attributed to more than one pathogenic organism. A better definition of the true incidence of mixed infections in community-acquired lower respiratory tract infections is partly derived from recent advances in available diagnostic methods (eg, molecular biology). Two points still must be determined: whether the presence of a mixed infection is associated with altered outcomes and whether empirical antibiotic selection should be modified to account for potential polymicrobial infections.
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Tarsia, P., Aliberti, S., Pappalettera, M. et al. Mixed community-acquired lower respiratory tract infections. Curr Infect Dis Rep 9, 14–20 (2007). https://doi.org/10.1007/s11908-007-0017-0
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DOI: https://doi.org/10.1007/s11908-007-0017-0