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Myocardial Fatigue at a Glance

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Abstract

Expanding on the modern lexicon of heart failure (HF), the novel mechano-energetic concept of myocardial fatigue describes a transiently energy-depleted myocardium with impaired contractility and relaxation in the face of adverse haemodynamic load. It encompasses established concepts of ventricular-arterial decoupling, deranged cardiac energetics and impaired myocardial efficiency, offering an alternative explanation for functional causes of HF.

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Authors and Affiliations

  1. University Hospital Coventry and Warwickshire, Clifford Bridge Road, Coventry, CV2 2DX, UK

    Patrick Tran & Prithwish Banerjee

  2. Centre for Sport, Exercise, Life Sciences, Faculty of Health and Life Sciences, Coventry University, Alison Gingell Building, Coventry, CV1 2DS, UK

    Patrick Tran & Prithwish Banerjee

  3. Warwick Medical School, University of Warwick, Coventry, CV4 7AL, UK

    Prithwish Banerjee

Authors
  1. Patrick Tran
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  2. Prithwish Banerjee
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Correspondence to Patrick Tran.

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Tran, P., Banerjee, P. Myocardial Fatigue at a Glance. Curr Heart Fail Rep 20, 191–193 (2023). https://doi.org/10.1007/s11897-023-00603-3

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  • DOI: https://doi.org/10.1007/s11897-023-00603-3

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