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Impact of Systemic Inflammation on the Progression of Gestational Diabetes Mellitus

  • Diabetes and Pregnancy (CJ Homko, Section Editor)
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Abstract

With increasing rates of obesity and new diagnostic criteria for gestational diabetes mellitus (GDM), the overall prevalence of GDM is increasing worldwide. Women with GDM have an increased risk of maternal and fetal complications during pregnancy as well as long-term risks including higher prevalence of type 2 diabetes mellitus and cardiovascular disease. In recent years, the role of immune activation and inflammation in the pathogenesis of GDM has gained increasing attention. This monograph explores the current state of the literature as regards the expression of markers of inflammation in the maternal circulation, placenta, and adipose tissue of women with GDM.

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The authors wish to acknowledge SERVIER Medical Art (www.servier.fr) for use of their medical art kits when making the illustration in the article.

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Authors and Affiliations

  1. Research Institute of Internal Medicine, Oslo University Hospital, Rikshospitalet, Sognsvannsveien 20, 0027, Oslo, Norway

    Tove Lekva, Pål Aukrust & Thor Ueland

  2. Mother Infant Research Institute, Tufts Medical Center, 800 Washington Street, Boston, MA, 02116, USA

    Tove Lekva & Errol R. Norwitz

  3. Department of Obstetrics & Gynecology, Tufts Medical Center and Tufts University School of Medicine, Boston, MA, USA

    Errol R. Norwitz

  4. Faculty of Medicine, University of Oslo, Oslo, Norway

    Pål Aukrust & Thor Ueland

  5. Section of Clinical Immunology and Infectious Diseases, Oslo University Hospital, Rikshospitalet, Oslo, Norway

    Pål Aukrust

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  1. Tove Lekva
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Lekva, T., Norwitz, E.R., Aukrust, P. et al. Impact of Systemic Inflammation on the Progression of Gestational Diabetes Mellitus. Curr Diab Rep 16, 26 (2016). https://doi.org/10.1007/s11892-016-0715-9

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