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Renal Artery Stenosis and Congestive Heart Failure: What Do We Really Know?

  • Peripheral Vascular Disease (CJ Cooper and R Gupta, Section Editors)
  • Published:
Current Cardiology Reports Aims and scope Submit manuscript

Abstract

Purpose of Review

Congestive heart failure (CHF) is a major cause of morbidity, mortality, and health care expenditure. Although the role of renal artery stenosis (RAS) in CHF has been known, there are a number of areas of uncertainty.

Recent Findings

The prevalence of RAS in subjects with CHF varies from 15 to 54% depending on the cohort studied and the diagnostic modality used to identify RAS. In subjects with CHF, the presence of RAS is associated with worse renal function and a higher risk for mortality during long-term follow-up.

Summary

There are many unanswered questions regarding the role of RAS in subjects with CHF. This review highlights those questions and helps to set the research agenda in this area.

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Authors and Affiliations

  1. Division of Cardiovascular Medicine, College of Medicine and Life Sciences, University of Toledo, 3000 Arlington Ave, MS# 1118, Toledo, OH, 43614, USA

    Rajesh Gupta & Mubbasher Syed

  2. Department of Medicine, College of Medicine and Life Sciences, University of Toledo, Toledo, OH, 43614, USA

    Nikita Ashcherkin, Katherine Chen, Palavi P. Vaidya & Christopher J. Cooper

Authors
  1. Rajesh Gupta
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  2. Mubbasher Syed
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  3. Nikita Ashcherkin
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  4. Katherine Chen
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  5. Palavi P. Vaidya
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  6. Christopher J. Cooper
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Corresponding author

Correspondence to Rajesh Gupta.

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Conflict of Interest

Christopher J. Cooper was the PI for the CORAL study. In addition, Dr. Cooper has a pending patent on Thermomorph.

Rajesh Gupta, Mubbasher Syed, Nikita Ashcherkin, Katherine Chen, and Palavi P. Vaidya declare that they have no conflict of interest.

Human and Animals Rights and Informed Consent

All reported studies with human or animal subjects performed by the authors have been previously published and complied with all applicable ethical standards (including the Helsinki declaration and its amendments, institutional and national research committee standards, and institutional research guidelines).

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This article is part of the Topical Collection on Peripheral Vascular Disease

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Gupta, R., Syed, M., Ashcherkin, N. et al. Renal Artery Stenosis and Congestive Heart Failure: What Do We Really Know?. Curr Cardiol Rep 21, 74 (2019). https://doi.org/10.1007/s11886-019-1169-x

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  • DOI: https://doi.org/10.1007/s11886-019-1169-x

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