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Does Parkinson’s disease affect sleep quality?

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Irish Journal of Medical Science (1971 -) Aims and scope Submit manuscript

Abstract

Background

Parkinson’s disease (PD) is a common neurodegenerative disease that is linked to several motor and nonmotor symptoms, including sleep disturbances. Patient quality of life has been shown to be disproportionally impacted by disease.

Objectives

To investigate sleep quality among individuals with PD, and to assess the severity of sleep disturbances and their impact on daytime activities.

Subjects and methods

A case‒control with 44 patients with Parkinson’s disease and 80 apparently healthy control participants was recruited from several hospitals and clinics. Each participant provided a thorough medical history and underwent a physical examination, and a questionnaire comprising the standard PSQI was used to assess sleep quality. Independent samples t test and Spearman’s correlation analysis were used with a p value equal to or less than 0.05 which was considered significant.

Results

The mean global PSQI score was 11.55 ± 4.412 for PD patients and 5.73 ± 3.22 for the control group with significant p value, Sleep latency onset was 75.57 min for PD patients and 22.81 min for the control group with significant p value. There was no significant correlation between age and other sleep-related variables. A total of 86.4% of patients with Parkinson’s disease suffered from varying degrees of daytime dysfunction compared to 61.25% of the controls.

Conclusion

Parkinson’s disease patients had poorer sleep quality than the controls. Age and sex were not found to be expected as a factor for sleep quality in patients with Parkinson’s disease. Daytime dysfunction rates are high in patients with Parkinson’s disease.

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Data availability

Data is available upon reasonable request.

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Acknowledgements

We would like to thank Dr. Maitham Fadhil, Dr. Bahaa Abdulameer, Dr. Mays Isam Alwash, and Dr. Muhammed Arif Hammadi. We also express our gratitude to all those who played a role in making this research possible.

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Authors and Affiliations

  1. Al-Kindy College of Medicine, University of Baghdad, Baghdad, Iraq

    Hussein A. Hammadi, Woruod Ahmed Hameed, Mohammed A. Fakhri, Hussein M. Khazaal, Fatima Kareem Abood, Ekhlas Khalid Hameed & Laith Thamer Al-Ameri

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  1. Hussein A. Hammadi
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  2. Woruod Ahmed Hameed
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  3. Mohammed A. Fakhri
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  4. Hussein M. Khazaal
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  5. Fatima Kareem Abood
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  6. Ekhlas Khalid Hameed
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  7. Laith Thamer Al-Ameri
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Contributions

HH, WH: data collection and assembling; MF, HK: writing; FA: data analysis; EH, LA: study design, review, editing, and critical appraising; all authors read and approve the final manuscript.

Corresponding author

Correspondence to Laith Thamer Al-Ameri.

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Ethical approval

Ethical approval was obtained from the ethical and scientific committee of the Al-Kindy College of Medicine, University of Baghdad.

Informed consent

Written consent was obtained from each enrolled individual after clarification of the study aims.

Competing interests

The authors declare no competing interests.

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Hammadi, H.A., Hameed, W.A., Fakhri, M.A. et al. Does Parkinson’s disease affect sleep quality?. Ir J Med Sci (2024). https://doi.org/10.1007/s11845-024-03689-3

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  • DOI: https://doi.org/10.1007/s11845-024-03689-3

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