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Impact of the 2016 World Health Organization Classification of Tumours of the Central Nervous System: an Irish experience

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Abstract

The 2016 World Health Organization Classification of Tumours of the Central Nervous System Tumours represents the most significant update to neuro-oncological tumour classification to date, compared with previous updates. This update reflects the substantial advances in molecular and genetic understanding of both adult and childhood brain tumours which have occurred in recent years. These advances have meant that an increasing array of molecular tests are required to definitively classify a tumour, allowing for a more precise integrated pathological diagnosis, but at the expense of a more challenging pathology workup. We review the changes incorporated into the 2016 classification and describe the impact of these changes in an Irish neuropathology laboratory.

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Authors and Affiliations

  1. Department of Neuropathology, Beaumont Hospital, Dublin, Ireland

    Conor Fearon, Teresa Loftus, Amber Lynn Byrne, Josephine Heffernan, Maeve Cooney, Ciara Heeney, Andrea Walsh, Jennifer Lorigan, Alan Beausang, Jane Cryan, Michael Farrell & Francesca Brett

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  1. Conor Fearon
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  2. Teresa Loftus
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  3. Amber Lynn Byrne
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Correspondence to Francesca Brett.

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Fearon, C., Loftus, T., Byrne, A.L. et al. Impact of the 2016 World Health Organization Classification of Tumours of the Central Nervous System: an Irish experience. Ir J Med Sci 189, 799–803 (2020). https://doi.org/10.1007/s11845-019-02144-y

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  • DOI: https://doi.org/10.1007/s11845-019-02144-y

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