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A retrospective audit of 200 cases of CNS tumours and their surgical management in a tertiary care centre

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Abstract

Aims

To study the nature of the tumours managed in the Irish population.

Methods

This audit research was completed via a retrospective medical review on 200 patients with CNS tumours managed in a tertiary care centre between 2008 and 2009.

Results

The mean age was 53 years. The male:female ratio was 2:1. The majority were glioblastomas and astrocytomas. Grade IV tumours were predominant (65.5 %). Headaches (37 %), motor weakness (32 %) and seizures (25.5 %) were the highest presentations. The commonest sites affected were the left parietal and left temporal lobes. There were 17.5 % operative morbidities with motor weakness (22.9 %), seizure (14.3 %) and thrombo-embolism (14.3 %) dominating and significant association to surgical radicality (p = 0.041). 3.5 % operative mortalities were reported. 52.5 and 62.5 % of patients received adjuvant chemotherapy and radiotherapy, respectively.

Conclusions

Patients with CNS tumours typically had multiple presentations. More extensive surgical resection was associated with higher postoperative morbidities (p = 0.041). The 30-day postoperative morbidity (17.5 %) and mortality (3.5 %) were concordant with the currently available literature.

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Correspondence to F. E. Muhamat Nor.

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Muhamat Nor, F.E., Chandrasekaran, K. & Marks, J.C. A retrospective audit of 200 cases of CNS tumours and their surgical management in a tertiary care centre. Ir J Med Sci 182, 697–701 (2013). https://doi.org/10.1007/s11845-013-0959-1

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  • DOI: https://doi.org/10.1007/s11845-013-0959-1

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