Abstract
Background
Ischaemia–reperfusion injury (I–R injury) is a recognised and potentially fatal complication following revascularisation of an ischaemic limb. Prevention of reperfusion injury is the focus of much research, but effective drug regimens have yet to be established into clinical practice.
Case report
Here we present a man with prolonged, severe lower limb ischaemia, successfully treated with a novel surgical technique for preventing I–R injury. Prior to revascularisation, the common femoral vein was cannulated and the harmful venous effluent was drained. The patient made an excellent recovery, the limb was salvaged and no systemic complications were encountered.
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References
Earnshaw J (2001) Demography and etiology of acute leg ischemia. Semin Vasc Surg 14:86–92
Blaisdell FW (2002) The pathophysiology of skeletal muscle ischemia and the reperfusion syndrome: a review. Cardiovasc Surg 10:620–630
Rutherford RB, Baker JD, Ernst C et al (1997) Recommended standards for reports dealing with lower extremity ischaemia: revised version. J Vasc Surg 26:517–538
Cerra FB, Lajos TZ, Montes M et al (1975) Hemorrhagic infarction: a reperfusion injury following prolonged myocardial ischemic anoxia. Surgery 78:95
Grace PA (1994) Ischaemia–reperfusion injury. Br J Surg 81(5):637–647
Grace PA, Da Costa M, Qureshi A, Sheehan S, Burke P, Bouchier-Hayes D (1993) An aggressive approach to acute superior mesenteric arterial ischemia. Eur J Vasc Surg 7(6):731–732
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Coakley, D.N., Moloney, T., McCormick, J. et al. Venous drainage, a simple method to prevent the systemic consequences of ischaemia–reperfusion injury in acute lower limb ischaemia. Ir J Med Sci 179, 131–133 (2010). https://doi.org/10.1007/s11845-009-0421-6
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DOI: https://doi.org/10.1007/s11845-009-0421-6