, Volume 64, Issue 4, pp 520–525 | Cite as

Ultrananocrystalline Diamond-Coated Microporous Silicon Nitride Membranes for Medical Implant Applications

  • Shelby A. Skoog
  • Anirudha V. Sumant
  • Nancy A. Monteiro-Riviere
  • Roger J. Narayan


Ultrananocrystalline diamond (UNCD) exhibits excellent biological and mechanical properties, which make it an appropriate choice for promoting epidermal cell migration on the surfaces of percutaneous implants. We deposited a ~150 nm thick UNCD film on a microporous silicon nitride membrane using microwave plasma chemical vapor deposition. Scanning electron microscopy and Raman spectroscopy were used to examine the pore structure and chemical bonding of this material, respectively. Growth of human epidermal keratinocytes on UNCD-coated microporous silicon nitride membranes and uncoated microporous silicon nitride membranes was compared using the 3-(4,5-dimethylthiazol-2-yl)2,5-diphenyltetrazolium bromide (MTT) assay. The results show that the UNCD coating did not significantly alter the viability of human epidermal keratinocytes, indicating potential use of this material for improving skin sealing around percutaneous implants.


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Copyright information

© TMS 2012

Authors and Affiliations

  • Shelby A. Skoog
    • 1
  • Anirudha V. Sumant
    • 2
  • Nancy A. Monteiro-Riviere
    • 1
    • 3
  • Roger J. Narayan
    • 1
  1. 1.Joint Department of Biomedical EngineeringUniversity of North Carolina and North Carolina State UniversityRaleighUSA
  2. 2.Center for Nanoscale MaterialsArgonne National LaboratoryArgonneUSA
  3. 3.Center for Chemical Toxicology Research and Pharmacokinetics, Department of Clinical SciencesNorth Carolina State UniversityRaleighUSA

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