Skip to main content
Log in

A paradigm for the integration of biology in materials science and engineering

  • Biological and Biomedical Materials / Overview
  • Published:
JOM Aims and scope Submit manuscript

Abstract

The integration of biology in materials science and engineering can be complicated by the lack of a common framework and common language between otherwise disparate disciplines. History may offer a valuable lesson as modern materials science and engineering itself resulted from the integration of traditionally disparate disciplines that were delineated by classes of materials. The integration of metallurgy, ceramics, and polymers into materials science and engineering was facilitated, in large part, by a unifying paradigm based upon processing-structure-property relationships that is now well-accepted. Therefore, a common paradigm might also help unify the vast array of perspectives and challenges present in the interdisciplinary study of biomaterials, biological materials, and biomimetic materials. The traditional materials science and engineering paradigm was modified to account for the adaptive and hierarchical nature of biological materials. Various examples of application to research and education are considered.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. R. Langer, “Biomaterials for Drug Delivery and Tissue Engineering,” MRS Bull., 31(6) (2006), pp. 477–485.

    CAS  Google Scholar 

  2. G.M. Whitesides and A.P. Wong, “The Intersection of Biology and Materials Science,” MRS Bull., 31(1) (2006), pp. 19–27.

    CAS  Google Scholar 

  3. M.H. Friedman, “Traditional Engineering in the Biological Century: The Biotraditional Engineer,” J. Biomech. Eng., 123(12) (2001), pp. 525–527.

    Article  CAS  PubMed  Google Scholar 

  4. L.E. Murr, “Biological Issues in Materials Science and Engineering: Interdisciplinarity and the Bio-Materials Paradigm,” JOM, 58(7) (2006), pp. 23–33.

    Article  CAS  Google Scholar 

  5. M.A. Meyers et al., “Biological Materials: Structure and Mechanical Properties,” Prog. Mater. Sci., 53 (2008), pp. 1–206.

    Article  CAS  Google Scholar 

  6. L.L. Hench and J.M. Polak, “Third-Generation Biomedical Materials,” Science, 295 (2002), pp. 1014–1017.

    Article  CAS  PubMed  ADS  Google Scholar 

  7. D.F. Williams, “On the Mechanisms of Biocompatibility,” Biomaterials, 29 (2008), pp. 2941–2953.

    Article  CAS  PubMed  Google Scholar 

  8. K.C. Dee and R. Bizios, “Mini-Review: Proactive Bio materials and Bone Tissue Engineering,” Biotechnol. Bioeng., 50(4) (1996), pp. 438–442.

    Article  CAS  PubMed  Google Scholar 

  9. D.L. Butler, S.A. Goldstein and F. Guilak, “Functional Tissue Engineering: The Role of Biomechanics,” J. Biomech. Eng., 122(12) (2000), pp. 570–575.

    Article  CAS  PubMed  Google Scholar 

  10. D. Peer et al., “Nanocarriers as an Emerging Platform for Cancer Therapy,” Nat. Nanotechnol., 2 (2007), pp. 751–760.

    Article  CAS  PubMed  ADS  Google Scholar 

  11. M. De, P.S. Ghosh, and V.M. Rotello, “Applications of Nanoparticles in Biology,” Adv. Mater, 20 (2008), pp. 4225–4241.

    Article  CAS  Google Scholar 

  12. P. Wu, D.G. Castner and D.W. Grainger, “Diagnostic Devices as Biomaterials: A Review of Nucleic Acid and Protein Microarray Surface Performance Issues,” J. Biomater. Sci. Polymer Ed, 19(6) (2008), pp. 725–753.

    Article  CAS  Google Scholar 

  13. M. Sarikaya et al., “Molecular Biomimetics: Nanotechnology through Biology,” Nat. Mater, 2 (2003), pp. 577–585.

    Article  CAS  PubMed  ADS  Google Scholar 

  14. D.F. Williams, The Williams Dictionary of Biomaterials (Liverpool, U.K.: Liverpool University Press, 1999).

    Google Scholar 

  15. M.A. Meyers, A.M. Hodge, and R.K. Roeder, “Biological Materials Science and Engineering: Biological Materials, Biomaterials, and Biomimetics,” JOM, 60(6) (2008), pp. 21–22.

    Article  Google Scholar 

  16. D.F. Williams, “On the Nature of Biomaterials,” Biomaterials, 30 (2009), pp. 5897–5909.

    Article  CAS  PubMed  Google Scholar 

  17. K.C. Dee, D.A Puleo, and R. Bizios, Tissue-Biomaterial Interactions (New York: John Wiley and Sons, 2002).

    Book  Google Scholar 

  18. M.C. Flemings, K.F. Jensen, and A. Mortensen, “Proposal for a Generic Materials Processing Course,” MRS Bull., 15(8) (1990), pp. 35–36.

    Google Scholar 

  19. G.L. Liedl, “The Emerging Undergraduate Curricula in Materials Science and Engineering,” MRS Bull., 15(8) (1990), pp. 31–34.

    Google Scholar 

  20. Materials and Man’s Needs: Materials Science and Engineering, Vol. 3, The Institutional Framework for Materials Science and Engineering, Supplementary Report of the Committee on the Survey of Materials Science and Engineering (Washington, D.C.: National Academy of Sciences, 1975), http://www.nap.edu/catalog/10438.html.

  21. Materials Science and Engineering for the 1990s: Maintaining Competitiveness in the Age of Materials (Washington, D.C.: National Academy Press, 1989), http://www.nap.edu/catalog/758.html.

  22. The Future of Materials Science and Materials Engineering Education, A report from the Workshop on Materials Science and Materials Engineering Education (Arlington, VA: National Science Foundation, 2008), httpj/www.nsf.gov/mps/dmr/mse_081709.pdf.

  23. L.H. Schwartz, “Undergraduate Materials Education 2010: Status and Recommendations,” JOM, 62(3) (2010), pp. 34–70.

    Article  Google Scholar 

  24. K.P. Trumble, K.J. Bowman, and D.R. Gaskell, “A General Materials Processing Curriculum,” J. Mater. Education, 18(3) (1996), pp. 117–123.

    Google Scholar 

  25. E. Arzt, “Biological and Artificial Attachment Devices: Lessons for Materials Scientists from Flies and Geckos,” Mater. Sci. Eng. C, 26 (2006), pp. 1245–1250.

    Article  CAS  Google Scholar 

  26. M.F. Ashby, Materials Selection in Mechanical De sign (Oxford, U.K.: Pergamon Press, 1992).

    Google Scholar 

  27. M.C.H. van der Meulen and R. Huiskes, “Why Mechanobiology? A Survey Article,” J. Biomechanics, 35(4) (2002), pp. 401–414.

    Article  Google Scholar 

  28. D.E. Stokes, Pasteur’s Quandrant: Basic Science and Technological Innovation (Washington, D.C.: Brookings Institute Press, 1997).

    Google Scholar 

  29. E. Hodnett, The Art of Problem Solving (New York: Harper, 1955).

    Google Scholar 

  30. B. Prasad, Concurrent Engineering Fundamentals. Integrated Product and Process Organization (Edgewood Cliffs, NJ: Prentice Hall, 1996).

    Google Scholar 

  31. B. Yazdani and C. Holmes, “Four Models of Design Definition: Sequential, Design Centered, Concur rent and Dynamic,” J. Eng. Design, 10(1) (1999), pp. 25–37.

    Article  Google Scholar 

  32. D. L. McDowell, “Simulation-Assisted Materials Design for the Concurrent Design of Materials and Products,” JOM, 59(9) (2007), pp. 21–25.

    Article  Google Scholar 

  33. G.B. Olson, “Computational Design of Hierarchically Structured Materials,” Science, 277 (1997), pp. 1237–1242.

    Article  CAS  Google Scholar 

  34. K. Thornton et al., “Computational Materials Science and Engineering Education: A Survey of Trends and Needs,” JOM, 61(10) (2009), pp. 12–17.

    Article  Google Scholar 

  35. J.A. Nychka and M.M. Gentleman, “Implications of Wettability in Biological Materials Science,” in this issue.

  36. K. Bowman, Mechanical Behavior of Materials (New York: John Wiley and Sons, Inc., 2004).

    Google Scholar 

  37. J.M. Deuerling et al., “Specimen-specific Multiscale Model for the Anisotropic Elastic Constants of Human Cortical Bone,” J. Biomechanics, 42(13) (2009), pp. 2061–2067.

    Article  Google Scholar 

  38. J.W. Ager III, G. Balooch, and R.O. Ritchie, “Fracture, Aging, and Disease in Bone,” J. Mater. Res., 21(8) (2006), pp. 1878–1892.

    Article  CAS  ADS  Google Scholar 

  39. J.J. Kruzic and R.O. Ritchie, “Fatigue of Mineralized Tissues: Cortical Bone and Dentin,” J. Mech. Behav. Biomed. Mater., 1(1) (2008), pp. 3–17.

    Article  CAS  PubMed  Google Scholar 

  40. L.M. Liz-Marzan, “Tailoring Surface Plasmons through the Morphology and Assembly of Metal Nanoparticles,” Langmuir, 22 (2006), pp. 32–41.

    Article  CAS  PubMed  Google Scholar 

  41. J. Andrade, “Biomaterials I: Past, Present, and Future,” Biomedical Engineering Education Summit (Arlington, VA: Whitaker Foundation, 2000).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Ryan K. Roeder.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Roeder, R.K. A paradigm for the integration of biology in materials science and engineering. JOM 62, 49–55 (2010). https://doi.org/10.1007/s11837-010-0108-5

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11837-010-0108-5

Keywords

Navigation