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Chemical functionalization and stabilization of type I collagen with organic tanning agents

  • Polymer, Industrial Chemistry
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Abstract

We investigated the interactions between selected organic tanning agents and type I fibrillar collagen as a model fibrillar substrate to enable the fast direct evaluation and validation of interpretations of tanning activity. Type I fibrillar collagen (1%) as gel was used as substrate of tanning and tannic acid, resorcinol- and melamine-formaldehyde and their combination at three concentrations as crosslinking agents (tannins). To evaluate the stability of collagen during tanning, the crosslinked gels at 2.8, 4.5 and 9.0 pHs were freeze-dried as discs which were characterized by FT-IR, shrinkage temperature, enzymatic degradation and optical microscopy, and the results were validated by statistical analyses. The best stability was given by combinations between resorcinol- and melamine-formaldehyde at isoelectric pH.

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Authors and Affiliations

  1. INCDTP — Leather and Footwear Research Institute, Bucharest, Romania

    Madalina Georgiana Albu, Viorica Deselnicu, Ioannis Ioannidis, Dana Deselnicu & Ciprian Chelaru

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  1. Madalina Georgiana Albu
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  2. Viorica Deselnicu
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  3. Ioannis Ioannidis
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  4. Dana Deselnicu
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  5. Ciprian Chelaru
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Correspondence to Madalina Georgiana Albu.

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Albu, M.G., Deselnicu, V., Ioannidis, I. et al. Chemical functionalization and stabilization of type I collagen with organic tanning agents. Korean J. Chem. Eng. 32, 354–361 (2015). https://doi.org/10.1007/s11814-014-0197-x

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  • DOI: https://doi.org/10.1007/s11814-014-0197-x

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