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Production of polyhydroxy fatty acids from linoleic acid by Clavibacter sp. ALA2

  • Published:
Journal of the American Oil Chemists' Society

Abstract

Hydroxy fatty acids are important industrial materials. We isolated a microbial culture, Clavibacter sp. ALA2, which converts linoleic acid to many polyhydroxy fatty acids. Structures of the products were determined as: 12,13,17-trihydroxy-9(Z)-octadecenoic (THOA, main product), 12-[5-ethyl-2-tetrahydrofuranyl]-7,12-dihydroxy-9(Z)-dodecenoic (ETDDA), and 12-[5-ethyl-2-tetrahydrofuranyl]-12-hydroxy-9(Z)-dodecenoic (ETHDA) acid. The yield of THOA was 25% and the relative amount of the products were THOA/ETDDA/ETHDA =9:1.3:1. The structures of the hydroxy unsaturated fatty acids resemble those of plant self-defense substances.

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Authors and Affiliations

  1. Bioactive Agents Research, NCAUR, ARS, USDA, 61604, Peoria, Illinois

    Harold Gardner

  2. Oil Chemical Research, NCAUR, ARS, USDA, 1815 N. University St., 61604, Peoria, IL

    Ching T. Hou & Wanda Brown

Authors
  1. Ching T. Hou
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  2. Harold Gardner
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  3. Wanda Brown
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Correspondence to Ching T. Hou.

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Hou, C.T., Gardner, H. & Brown, W. Production of polyhydroxy fatty acids from linoleic acid by Clavibacter sp. ALA2. J Amer Oil Chem Soc 75, 1483–1487 (1998). https://doi.org/10.1007/s11746-998-0082-z

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  • DOI: https://doi.org/10.1007/s11746-998-0082-z

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