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Maternal dietary alpine butter intake affects human milk: Fatty acids and conjugated linoleic acid isomers

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Lipids

Abstract

Consumption of CLA by lactating women affects the composition of their milk, but the pattern of the different CLA isomers is still unknown. We determined the effects of short maternal supplementation with CLA-rich Alpine butter on the occurrence of FA and CLA isomers in human milk. In an open randomized controlled study with a two-period cross-over design, milk FA and CLA isomer concentrations were measured on postpartum days >-20 in two parallel groups of lactating women before, during, and after consumption of defined quantities of Alpine butter or margarine with comparable fat content (10 d of butter followed by 10 d of margarine for one group, and vice versa in the other). In the 16 women who completed the study (8/group), Alpine butter supplementation, increased the C16 and C18 FA, the sum of saturated FA, the 18∶1 trans FA, and the trans FA with CLA. The CLA isomer 18∶2 c9, t11 increased by 19.7%. Significant increases were also found for the isomers t9,t111, t7,c9,t11,c13, and t8,c10 18∶2. The remaining nine of the total 14 detectable isomers showed no changes, and concentrations were <5 mg/100g fat. A breastfeeding mother can therefore modulate the FA/CLA supply of her child by consuming Alpine butter. Further studies will show whether human milk containing this FA and CLA isomer pattern acts as a functional food for newborns.

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Abbreviations

BMI:

body mass index

CLA:

conjugated linoleic acid

EFA:

essential fatty acid

FA:

fatty acid

GC:

gas chromatography(y)

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Author information

Authors and Affiliations

  1. Department of Obstetrics, Zurich University Hospital, CH-8091, Zürich, Switzerland

    Isabelle Bertschi & Ursula von Mandach

  2. Agroscope Liebefeld-Posieux, Swiss Federal Research Station for Animal Production and Dairy Products (ALP), CH-3003, Berne

    Marius Collomb, Pius Eberhard, Robert Sieber, Ulrich Bütikofer & Daniel Wechsler

  3. Paracelsus Hospital, CH-8805, Richterswil

    Lukas Rist

  4. Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology Zurich, CH-8092, Zurich, Switzerland

    Gerd Folkers

Authors
  1. Isabelle Bertschi
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  2. Marius Collomb
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  3. Lukas Rist
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  4. Pius Eberhard
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  6. Ulrich Bütikofer
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  9. Ursula von Mandach
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Correspondence to Ursula von Mandach.

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Bertschi, I., Collomb, M., Rist, L. et al. Maternal dietary alpine butter intake affects human milk: Fatty acids and conjugated linoleic acid isomers. Lipids 40, 581–587 (2005). https://doi.org/10.1007/s11745-005-1419-8

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  • DOI: https://doi.org/10.1007/s11745-005-1419-8

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