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Effects of intermittent cycle exercise on intramyocellular lipid use and recovery

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Lipids

Abstract

The purpose of this investigation was to compare intramyocellular lipid (IMCL) changes in skeletal muscle in nine moderately trained subjects after 45 min of interval cycling and through 1 h of recovery. The exercise session was continous with alternating cycling intensity achieving 50 (3 min) and 110% (2 min) of ventilatory threshold. Spectra from the vastus lateralis were acquired before, immediately after, and 60 min following exercise using a 1.5 T Signa whole-body magnet (point-resolved spectroscopy sequence, echo time 60 ms, transverse relaxation time 2000 ms, 128 acquisitions, and 20 mm3 voxel). Immediately following exercise, IMCI concentration decreased 38% compared to pre-exercise levels (P<0.05). Fitness level and baseline IMCL were not correlated with changes in IMCL following exercise (P>0.05). In the 60-min recovery, IMCL was reduced 30% compared to baseline (P<0.05) and did not recover. In contrast, a nonexercising control group showed no change in IMCL. Our results suggest that IMCL decreased significantly following 45 min of interval cycling, with little recovery in the hour following.

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Abbreviations

aHSL:

adipocyte hormone-sensitive lipase

AU:

arbitrary units

BF:

body fat

EMCL:

extramyocellular lipid

IMCL:

intramyocellular lipid

mHSL:

muscle hormone-sensitive lipase

H MRS:

proton magnetic resonance spectroscopy

RER:

respiratory exchange ratio

VE :

minute ventidation

VCO2 :

carbon dioxide production

VO2 :

oxygen consumption

VO2max :

maximal oxygen consumption

VT:

ventilatory threshold

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Authors and Affiliations

  1. Human Performance Laboratory, University of New Mexico, P.O. Box 118206, 87106, Albuquerque, New Mexico

    Lesley J. White & Robert A. Robergs

  2. Clinical and Magnetic Resonance Research Center, University of New Mexico, P.O. Box 118206, 87106, Albuquerque, New Mexico

    Wilmer L. Sibbitt Jr. & William M. Brooks

  3. Department of Internal Medicine, University of New Mexico, P.O. Box 118206, 87106, Albuquerque, New Mexico

    Lesley J. White, Wilmer L. Sibbitt Jr. & Sean McCoy

  4. Department Neurosciences, University of New Mexico, P.O. Box 118206, 87106, Albuquerque, New Mexico

    William M. Brooks

  5. Department of Exercise & Sport Sciences, University of Florida, P.O. Box 118206, 32611, Gainesville, Florida

    Lesley J. White & Michael A. Ferguson

  6. Hoglund Brain Imaging Center, University of Kansas Medical Center, 66160, Kansas City, Kansas

    William M. Brooks

Authors
  1. Lesley J. White
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  2. Robert A. Robergs
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  3. Wilmer L. Sibbitt Jr.
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  4. Michael A. Ferguson
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  5. Sean McCoy
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Correspondence to Lesley J. White.

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White, L.J., Robergs, R.A., Sibbitt, W.L. et al. Effects of intermittent cycle exercise on intramyocellular lipid use and recovery. Lipids 38, 9–13 (2003). https://doi.org/10.1007/s11745-003-1024-x

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  • DOI: https://doi.org/10.1007/s11745-003-1024-x

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