, Volume 38, Issue 1, pp 9–13 | Cite as

Effects of intermittent cycle exercise on intramyocellular lipid use and recovery

  • Lesley J. White
  • Robert A. Robergs
  • Wilmer L. SibbittJr.
  • Michael A. Ferguson
  • Sean McCoy
  • William M. Brooks


The purpose of this investigation was to compare intramyocellular lipid (IMCL) changes in skeletal muscle in nine moderately trained subjects after 45 min of interval cycling and through 1 h of recovery. The exercise session was continous with alternating cycling intensity achieving 50 (3 min) and 110% (2 min) of ventilatory threshold. Spectra from the vastus lateralis were acquired before, immediately after, and 60 min following exercise using a 1.5 T Signa whole-body magnet (point-resolved spectroscopy sequence, echo time 60 ms, transverse relaxation time 2000 ms, 128 acquisitions, and 20 mm3 voxel). Immediately following exercise, IMCI concentration decreased 38% compared to pre-exercise levels (P<0.05). Fitness level and baseline IMCL were not correlated with changes in IMCL following exercise (P>0.05). In the 60-min recovery, IMCL was reduced 30% compared to baseline (P<0.05) and did not recover. In contrast, a nonexercising control group showed no change in IMCL. Our results suggest that IMCL decreased significantly following 45 min of interval cycling, with little recovery in the hour following.


Vastus Lateralis Ventilatory Threshold Trained Subject Intramyocellular Lipid Interval Cycling 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



adipocyte hormone-sensitive lipase


arbitrary units


body fat


extramyocellular lipid


intramyocellular lipid


muscle hormone-sensitive lipase


proton magnetic resonance spectroscopy


respiratory exchange ratio


minute ventidation


carbon dioxide production


oxygen consumption


maximal oxygen consumption


ventilatory threshold


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Copyright information

© AOCS Press 2003

Authors and Affiliations

  • Lesley J. White
    • 1
    • 3
    • 5
  • Robert A. Robergs
    • 1
  • Wilmer L. SibbittJr.
    • 2
    • 3
  • Michael A. Ferguson
    • 5
  • Sean McCoy
    • 3
  • William M. Brooks
    • 2
    • 4
    • 6
  1. 1.Human Performance LaboratoryUniversity of New MexicoAlbuquerque
  2. 2.Clinical and Magnetic Resonance Research CenterUniversity of New MexicoAlbuquerque
  3. 3.Department of Internal MedicineUniversity of New MexicoAlbuquerque
  4. 4.Department NeurosciencesUniversity of New MexicoAlbuquerque
  5. 5.Department of Exercise & Sport SciencesUniversity of FloridaGainesville
  6. 6.Hoglund Brain Imaging CenterUniversity of Kansas Medical CenterKansas City

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