Abstract
In this study, iron oxide (Fe3O4), cuprous oxide (Cu2O), and silver (Ag) nanoparticles were synthesized during a simple and green method mediated by the aqueous extract of Froriepia subpinnata. The synthesized nanoparticles were characterized by ultraviolet–visible (UV–Vis) and fourier-transform infrared (FT-IR) spectroscopy, X-ray diffraction (XRD) analysis, scanning electron microscopy (SEM), and transmission electron microscopy (TEM) techniques. The antimicrobial activity of the synthesized nanoparticles and F. subpinnata aqueous extract was studied against some bacteria and fungi using the disk diffusion method. The Cu2O and Ag nanoparticles were highly effective against the tested pathogenic microorganisms. The diameter of the inhibition zone by the Cu2O nanoparticles against Staphylococcus group A was measured to be 18 mm, almost equal to the result obtained using Penicillin-G as a reference. The aqueous extract of F. subpinnata was also evaluated on growth inhibition of cell line A549 by the MTT in vitro assay. The half-maximal inhibitory concentration (IC50) was calculated to be 48.32 ± 0.13 μg.ml−1. Furthermore, the potential of synthesized Fe3O4 nanoparticles to adsorb the Azo dye Acid-Red 58 from the aqueous media was satisfactory.
Graphical abstract
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Ahmed S, Annu S, Yudha SS (2016) Biosynthesis of gold nanoparticles: a green approach. J Photochem Photobiol B Biol 161:141–153. https://doi.org/10.1016/j.jphotobiol.2016.04.034
Akintelu SA, Folorunso AS, Folorunso FA, Oyebamiji AK (2020) Green synthesis of copper oxide nanoparticles for biomedical application and environmental remediation. Heliyon 6:e04508. https://doi.org/10.1016/j.heliyon.2020.e04508
Ameen F, Alsamhary KI, Alabdullatif JA, AL-Nadhari S (2021) A review on metal-based nanoparticles and their toxicity to beneficial soil bacteria and fungi. Ecotoxicol Environ Saf 213:112027. https://doi.org/10.1016/j.ecoenv.2021.112027
Ari H, Alani OA, Zeng Q, Ay U, Offiong NA, Feng W (2022) Enhanced UV-assisted Fenton performance of nanostructured biomimetic α-Fe2O3 on degradation of tetracycline. J Nanostruct Chem 12:45–58. https://doi.org/10.1007/s40097-021-00400-1
Ashfaq A, Khursheed N, Fatima S, Anjum Z, Younis K (2022) Application of nanotechnology in food packaging: pros and cons. J Agric Food Res 7:100270. https://doi.org/10.1016/j.jafr.2022.100270
Bahrami A, Jamzad M, Sedaghat S (2021) Phytochemicals and Biological Activities of Froriepia subpinnata (Ledeb.) Baill Extracts. J Med Plants Prod 10:109–115. https://doi.org/10.22092/jmpb.2020.352614.1295
Bauer AW, Kirby WMM, Sherris JC, Truch M (1996) Antibiotic susceptibility testing by standardized single disk method. Am J Clin Pathol 45:493–496
Behara M, Giri G (2014) Green synthesis and characterization of cuprous oxide nanoparticles in presence of a bio-surfactant. Mater Sci-Pol 32(4):702–708. https://doi.org/10.2478/s13536-014-0255-4
Behera M, Giri G (2014) Green synthesis and characterization of cuprous oxide nanoparticles in presence of a bio-surfactant. Mater Sci-Poland 32:702–708. https://doi.org/10.2478/s13536-014-0255-4
Das C, Sen S, Singh T, Ghosh T, Paul SS, Kim TW, Jeon S, Maiti DK, Im J, Biswas G (2020) Green synthesis, characterization and application of natural product coated magnetite nanoparticles for wastewater treatment. Nanomaterials 10(8):1615. https://doi.org/10.3390/nano10081615
Devika R, Chauhan S, Subbaiya R (2019) Biosynthesis of copper nanoparticle using Nerium oleander. Res J Pharm Technol 12:621–624. https://doi.org/10.5958/0974-360X.2019.00110.0
Dhananjayan B, Asharani I (2016) Dye degradation studies catalysed by green synthesized iron oxide nanoparticles. Int J ChemTech Res 9:409–416
Ebrahimzadeh MA, Nabavi SM, Nabavi SF, Eslami S, Bekhradnia A (2010) Mineral elements and antioxidant activity of three locally edible and medicinal plants in Iran. Asian J Chem 22:6257–6266
Fakhari S, Jamzad M, Kabiri-Fard H (2019) Green synthesis of zinc oxide nanoparticles: a comparison. Green Chem Lett & Rev 12:19–24. https://doi.org/10.1080/17518253.2018.1547925
Firoozi S, Jamzad M, Yari M (2016) Biologically synthesized silver nanoparticles by aqueous extract of Satureja intermedia C.A. Mey and the evaluation of total phenolic and flavonoid contents and antioxidant activity. J Nanostruct Chem 6:357–364. https://doi.org/10.1007/s40097-016-0207-0
Ge L, Li Q, Wang M, Ouyang J, Li X, Xing MMQ (2014) Nanosilver particles in medical applications: synthesis, performance, and toxicity. Int J Nanomed 9:2399–2407. https://doi.org/10.2147/IJN.S55015
Ghasemi M, Turnbull T, Sebastian S, Kempson I (2021) The MTT assay: utility, limitations, pitfalls, and interpretation in bulk and single-cell analysis. Int J Mol Sci 22(23):12827. https://doi.org/10.3390/ijms222312827
Gopinath M, Subbaiya R, Selvam MM, Suresh D, Rangasamy K (2014) Synthesis of copper nanoparticles from Nerium oleander leaf aqueous extract and its antibacterial activity. Int J Curr Microbiol Appl Sci 3:814–818
Gulbagca F, Ozdemir S, Gulcan M, Sen F (2019) Synthesis and characterization of Rosa canina-mediated biogenic silver nanoparticles for anti-oxidant, antibacterial, antifungal, and DNA cleavage activities. Heliyon 5(12):e02980. https://doi.org/10.1016/j.heliyon.2019.e02980
Helmi H, Falaki F, Karimi M, Babaloii F (2017) Highly facile removal of Acid Red 88 from aqueous samples by using synthesized iron oxide magnetic nanoparticles and 1-butyl-3- methylimidazolium tetrachloroferrate magnetic ionic liquid. Desalin Water Treat 90:331–340. https://doi.org/10.5004/dwt.2017.21321
Huy TQ, Huyen PTM, Le AT, Tonezzer M (2020) Recent advances of silver nanoparticles in cancer diagnosis and treatment. Anticancer Agents Med Chem 20(11):1276–1287. https://doi.org/10.2174/1871520619666190710121727
Ismail MIM (2020) Green synthesis and characterizations of copper nanoparticles. Mater Chem Phys 240:122283. https://doi.org/10.1016/j.matchemphys.2019.122283
Jadidi Kouhbanani MA, Beheshtkhoo N, Taghizadeh S, Amani AM, Alimardani V (2019) One-step green synthesis and characterization of iron oxide nanoparticles using aqueous leaf extract of Teucrium polium and their catalytic application in dye degradation. Adv Nat Sci: Nanosci Nanotechnol 10(1):015007. https://doi.org/10.1088/2043-6254/aafe74
Jin Y, Li B, Saravanakumar K, Hu X, Mariadoss AVA, Wang MH (2022) Cytotoxic and antibacterial activities of starch encapsulated photo-catalyzed phytogenic silver nanoparticles from Paeonia lactiflora flowers. J Nanostruct Chem 12:375–387. https://doi.org/10.1007/s40097-021-00421-w
Khan I, Bawazeer S, Rauf A, Qureshi MN, Muhammad N, Al-Awthan YS, Bahatab O, Maleek A, Kannan R, Rengasamy R (2022) Synthesis, biological investigation and catalytic application using the alcoholic extract of Black Cumin (Bunium persicum) seeds-based silver nanoparticles. J Nanostruct Chem 12:59–77. https://doi.org/10.1007/s40097-021-00402-z
Khani R, Roostaei B, Bagherzade G, Moudi M (2018) Green synthesis of copper nanoparticles by fruit extract of Ziziphus spinachristi (L.) Willd: Application for adsorption of triphenylmethane dye and antibacterial assay. J Mol Liq 255:541–549. https://doi.org/10.1016/j.molliq.2018.02.010
Kinnear C, Moore TL, Rodriguez-Lorenzo L, Rothen-Rutishauser B, Petri-Fink A (2017) form follows function: nanoparticle shape and its implications for nanomedicine. Chem Rev 117:11476–11521. https://doi.org/10.1021/acs.chemrev.7b00194
Lasemi Z, Azimi R, Sadeghi B, Oshri M (2017) Green synthesis of silver nanoparticles using aqueous extract of Froripia subpinnata and evaluation of their antibacterial activity. Inorg Nano-Met Chem 47:1412–1417. https://doi.org/10.1080/24701556.2017.1291680
Leute GH (1987) Froriepia. In: Hedge IC, Lamond JM, Rechinger KH (eds) Flora Iranica. Academische Druck and Verlagsanstalt, Graz, Austria, Umbelliferae, p 297
Li P, Lv W, Ai S (2016) Green and gentle synthesis of Cu2O nanoparticles using lignin as reducing and capping reagent with antibacterial properties. J Exp Nanosci 11:18–27. https://doi.org/10.1080/17458080.2015.1015462
Lohrasbi S, Jadidi Kouhbanani MA, Beheshtkhoo N, Ghasemi Y, Amani AM, Taghizadeh S (2019) Green synthesis of iron nanoparticles using plantago major leaf extract and their application as a catalyst for the decolorization of azo dye. BioNanoScience 9(2):317–322
Mahdavi M, Namvar F, Bin-Ahmad M, Mohammad R (2013) Green biosynthesis and characterization of magnetic Iron oxide (Fe3O4) nanoparticles using seaweed (Sargasuum muticum) aqueous extract. Molecules 18:5954–5964. https://doi.org/10.3390/molecules18055954
Mehrabanjoubani P, Ghorbani Nohooji M, Karimi E, Ahmad Abdolzadeh A (2021) The differences between Froriepia subpinnata (Ledeb.) Baill. and Pimpinella anisum L. commonly named as anarijeh based on major components of the essential oil; a marker for resolve ambiguities. J Med Plants 20:59–71
Mirzania F, Sarrafi Y, Moridi Farimani M (2019) Comparative evaluation of chemical compositions and biological activities of wild and cultivated Froriepia subpinnata L. essential oils. J Agric Sci Technol 21:331–340
Mohammadzadeh M, Mahmoudi R, Ghajarbeygi P (2018) Evaluation of chemical composition and antibacterial properties of Froriepia subpinnta essential oils from Guilan region: before and after flowering. J Essent Oil-Bear Plants 21:1119–1127. https://doi.org/10.1080/0972060X.2018.1505555
Morteza-Semnani K, Saeedi M, Akbarzadeh M (2009) The essential oil composition of Froriepia subpinnata (Ledeb.) Baill. J Essent Oil Res 21:127–128. https://doi.org/10.1080/10412905.2009.9700129
Mosmann T (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65:55–63. https://doi.org/10.1016/0022-1759(83)90303-4
Mozaffarian V (2007) Umbelliferae. In: Assadi M, Khatamsaz M, Maasoumi AA (Eds) Flora of Iran, No. 54. Research Institute of Forests and Rangelands Publication, Tehran, Iran
Padma PN, Banu TS, Kumari SC (2018) Studies on green synthesis of copper nanoparticles using Punica granatum. Annu Res Rev Biol 23(1):1–10. https://doi.org/10.9734/ARRB/2018/38894
Ramesh AV, Rama Devi D, Mohan Botsa S, Basavaiah K (2018) Facile green synthesis of Fe3O4 nanoparticles using aqueous leaf extract of Zanthoxylum armatum DC. for efficient adsorption of methylene blue. J Asian Ceram Soc 6:145–155. https://doi.org/10.1080/21870764.2018.1459335
Revia RA, Zhang M (2016) Magnetite nanoparticles for cancer diagnosis, treatment, and treatment monitoring: recent advances. Mater Today 19(3):157–168. https://doi.org/10.1016/j.mattod.2015.08.022
Ruíz-Baltazar ADJ, Reyes-López SY, Mondragón-Sánchez MDL, Robles-Cortés AI, Pérez R (2019) Eco-friendly synthesis of Fe3O4 nanoparticles: evaluation of their catalytic activity in methylene blue degradation by kinetic adsorption models. Results Phys 12:989–995. https://doi.org/10.1016/j.rinp.2018.12.037
Rustaiyan A, Mojab R, Kazemie-Piersara M, Bigdeli M, Masoudi S, Yari M (2001) Essential oil of Froriepia subpinnata (Ledeb.) Baill. from Iran. J Essent Oil Res 13:405–406. https://doi.org/10.1080/10412905.2001.9699707
Sankarganesh P, Kumar AG, Parthasarathy V, Joseph B, Priyadharsini G, Anbarasan R (2021) Synthesis of Murraya koenigii mediated silver nanoparticles and their in-vitro and in-vivo biological potential. J Inorg Organomet Polym Mater 31:2971–2979. https://doi.org/10.1007/s10904-021-01894-6
Sawant SS, Bhagwat AD, Mahajan CM (2016) Synthesis of Cuprous Oxide (Cu2O) nanoparticles-a review. J Nano-Electron Phys 8(1):01035. https://doi.org/10.21272/jnep.8(1).01035
Seyyed Abadi M, Asadi Amirabadi A, Taheri A, Kashaninezhad M (2016) Investigation of infrared radiation on drying kinetics and color indexes of Anaryjeh (Froriepia subpinnata) leaf. Innov Food Technol 13:45–57
Shaker Ardakani L, Alimardani V, Tamaddon AM, Amani AM, Taghizadeh S (2021) Green synthesis of iron-based nanoparticles using Chlorophytum comosum leaf extract: methyl orange dye degradation and antimicrobial properties. Heliyon 7(2):e06159. https://doi.org/10.1016/j.heliyon.2021.e06159
Sharifi-Rad M, Pohl P, Epifano F, Alvarez-Suarez JM (2020) Green synthesis of silver nanoparticles using Astragalus tribuloides Delile. Root extract: characterization, antioxidant, antibacterial, and anti-inflammatory activities. Nanomaterials 10(12):2383. https://doi.org/10.3390/nano10122383
Shivaji S, Madhu S, Singh S (2011) Extracellular synthesis of antibacterial silver nanoparticles using psychrophilic bacteria. Process Biochem 46:1800–1807. https://doi.org/10.1016/j.procbio.2011.06.008
Thakur S, Sharma S, Thakur S, Rai R (2018) Green synthesis of copper nanoparticles using Asparagus adscendens Roxb. root and leaf extract and their antimicrobial activities. Int J Curr Microbiol App Sci 7:683–694. https://doi.org/10.20546/ijcmas.2018.704.077
Tsarfati Y, Rosenne S, Weissman H, Shimon LJW, Gur D, Palmer BA, Rybtchinski B (2018) Crystallization of organic molecules: nonclassical mechanism revealed by direct imaging. ACS Cent Sci 4:1031–1036. https://doi.org/10.1021/acscentsci.8b00289
Vaseghi Z, Tavakoli O, Nematollahzadeh A (2018) Rapid biosynthesis of novel Cu/Cr/Ni trimetallic oxide nanoparticles with antimicrobial activity. J Environ Chem Engin 6:1898–1911. https://doi.org/10.1016/J.JECE.2018.02.038
Vijay Kumar PPN, Kalyani RL, Chandra Veerla S, Kollu P, Shameem U, Pammi SVN (2019) Biogenic synthesis of stable silver nanoparticles via Asparagus racemosus root extract and their antibacterial efficacy towards human and fish bacterial pathogens. Mater Res Express 6:104008. https://doi.org/10.1088/2053-1591/ab3ce9
Wiley BJ, Im SH, Li ZY, McLellan J, Siekkinen A, Xia Y (2006) Maneuvering the surface Plasmon resonance of silver nanostructures through shape-controlled synthesis. J Phys Chem 110:15666–15675. https://doi.org/10.1021/jp0608628
Yugandhar P, Vasavi T, Maheswari Devi PU, Savithramma N (2017) Bioinspired green synthesis of copper oxide nanoparticles from Syzygium alternifolium (Wt.) Walp: characterization and evaluation of its synergistic antimicrobial and anticancer activity. Appl Nanosci 7:417–427. https://doi.org/10.1007/s13204-017-0584-9
Acknowledgements
We are thankful to Dr. Ziba Jamzad for plant identification and specimen deposition in the herbarium of the Research Institute of Forests & Rangelands, Tehran, Iran (TARI).
Author information
Authors and Affiliations
Contributions
MJ contributed to the conceptualization; BM and PSM were involved in the methodology; MJ and PSM helped in the formal analysis and investigation; MJ and BM contributed to writing—original draft preparation; MJ was involved in writing—review and editing.
Corresponding author
Ethics declarations
Conflict of interest
The authors declare that there is no conflict of interest.
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
About this article
Cite this article
Jamzad, M., Mokhtari, B. & Mirkhani, PS. Green synthesis of metal nanoparticles mediated by a versatile medicinal plant extract. Chem. Pap. 77, 1455–1467 (2023). https://doi.org/10.1007/s11696-022-02465-w
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11696-022-02465-w