Abstract
The deposition of polyaniline (PANI) onto the surface of plasticized poly(vinyl chloride) (PVC) membranes requires optimizing the membrane composition. Controlling the ratio between the plasticizer and PVC enables the hydrophilic surface to be prepared and a homogeneous PANI film to be deposited through chemical polymerization. Our studies showed that such modified PVC membranes can be used for the potentiometric detection of three tumor markers (TMs) that are metabolites of catecholamines and serves as a screening test for neuroblastoma. Furthermore, the interactions of PANI with these TMs were proved by a capillary electrophoresis method in which a capillary covered with PANI was used.
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Acknowledgements
This research was supported by the Grant Agency of the Czech Republic (Project P206/15/02815S) and by specific university research (MSMT No. 20-SVV/2016). Authors thank Prof. N. Gospodinova for AFM characterization of PANI and a helpful discussion of the obtained results.
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Shishkanová, T.V., Řezanková, K. & Řezanka, P. Influence of surface properties on the deposition of a polyaniline film and detection of tumor markers. Chem. Pap. 71, 489–494 (2017). https://doi.org/10.1007/s11696-016-0067-6
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DOI: https://doi.org/10.1007/s11696-016-0067-6