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The Efficacy and Safety of Laparoscopic Single-Anastomosis Duodeno-ileostomy with Sleeve Gastrectomy (SADI-S) in Mid- and Long-Term Follow-Up: a Systematic Review

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Abstract

This systematic review of 10 studies aimed to investigate the mid- and long-term results of duodeno-ileostomy with sleeve gastrectomy (SADI-S) according to the PRISMA guideline. Related articles, which reported outcomes of laparoscopic SADI-S with follow-up ≥ 3 years, were selected and analyzed. The percentage of excess weight loss (EWL) was 70.9–88.7%, and 80.4% at 6, and 10 years, respectively. The more common late complications were malabsorption (6.3%) and gastroesophageal reflux disease (GERD) (3.6%). The remission rates of hypertension, diabetes, GERD, obstructive sleep apnea, and dyslipidemia were 62.9%, 81.3%, 53.2%, 60.9%, and 69.7%, respectively. In conclusion, SADI-S is a safe and effective surgical technique with durable weight loss and a high rate of comorbidity resolution in mid and long term.

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Data Availability

The data that support the findings of this study are available on request from the corresponding author.

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Author information

Authors and Affiliations

  1. Student Research Committee, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

    Ali Esparham, Samira Roohi, Soheil Ahmadyar & Hengameh Anari Moghadam

  2. Department of General Surgery, School of Medicine, Surgical Oncology Research Center, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran

    Amin Dalili

  3. General and Digestive Surgery Service, Hospital Clínico San Carlos, Department of Surgery, Complutense University Medical School, Universidad Complutense de Madrid (UCM), IdISSC, Madrid, Spain

    Antonio José Torres

  4. Department of Surgery, University of Oklahoma School of Community Medicine, Tulsa, OK, USA

    Zhamak Khorgami

  5. Harold Hamm Diabetes Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA

    Zhamak Khorgami

  6. Department of Surgery, University of Oklahoma School of Community Medicine, Tulsa, OK, 1919 S. Wheeling Avenue, Suite 600, Tulsa, OK, USA

    Zhamak Khorgami

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  1. Ali Esparham
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  7. Zhamak Khorgami
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Correspondence to Zhamak Khorgami.

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Key Points

• The SADI-S surgical technique is safe and effective, providing significant sustained mid- and long-term weight loss and resolution of comorbidities.

• SADI-S can be performed as safe and effective revisional surgery after sleeve gastrectomy.

• SADI-S should be performed in appropriately selected patients with dietary and follow-up compliance.

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Esparham, A., Roohi, S., Ahmadyar, S. et al. The Efficacy and Safety of Laparoscopic Single-Anastomosis Duodeno-ileostomy with Sleeve Gastrectomy (SADI-S) in Mid- and Long-Term Follow-Up: a Systematic Review. OBES SURG 33, 4070–4079 (2023). https://doi.org/10.1007/s11695-023-06846-2

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