Abstract
Background
Revisional surgery is a second-line treatment option after sleeve gastrectomy (SG) and gastric bypass (GBP) in patients with primary or secondary non-response. The aim was to analyze the theoretical need for revisional surgery after SG and GBP when applying four indication benchmarks.
Method
Based on data from the Scandinavian Obesity Surgery Registry, SG and GBP were compared regarding four endpoints: 1. excess weight loss (%EWL) < 50%, 2. weight regain of more than 10 kg after nadir, 3. fulfillment of previous IFSO-guidelines, or 4. ADA criteria for bariatric metabolic surgery 2 years after primary surgery.
Results
A total of 60,426 individuals were included in the study (SG: n = 7856 and GBP: n = 52,570). Compared to patients in the GBP group, more SG patients failed to achieve a %EWL > 50% (23.0% versus 8.5%, p < .001), regained more than 10 kg after nadir (4.3% versus 2.5%, p < .001), and more often fulfilled the IFSO criteria (8.0% versus 4.5%, p < .001) or the ADA criteria (3.3% versus 1.8%, p < 001) at the 2-year follow-up.
Conclusion
SG is associated with a higher risk for weight non-response compared to GBP. To offer revisional bariatric surgery to all non-responders exceeds the bounds of feasibility and operability. Hence, individual prioritization and intensified evaluation of alternative second-line treatments are necessary.
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Introduction
With the increasing number of bariatric procedures performed worldwide, outcomes and indications for revisional procedures have gained more interest in the literature.
As a rule, long-term complications of bariatric operations can be resolved or at least improved by surgical procedures classified as corrective, conversional, or reversal [1]. Discussions revolve around aspects such as timing, patient optimization, type of procedure, and centralization to high volume centers [2].
On the other hand, the surgical treatment of relapse or persistence of obesity and its related diseases is a highly controversial topic. Although the bariatric community has put much effort into introducing scientifically robust guidelines, there is still profound disagreement regarding nomenclature, outcome measures, type of second-line treatment, and the patient’s ability to contribute to treatment results. Poor weight loss results and complication rates after revisional bariatric metabolic surgery have probably contributed to a certain degree of reluctance among some bariatric surgeons [3, 4].
This Swedish study estimates the theoretical need for a surgical second-line treatment after previous bariatric metabolic surgery using indications based on different guidelines and definitions. It is assumed that the previous IFSO and American Diabetes Association (ADA) guidelines regarding the indication for bariatric surgery pertain equally to primary and secondary surgery. Moreover, the study utilized two of the most frequently reported indications for revisional bariatric metabolic surgery based on treatment outcomes.
Material and Methods
Data Source and Study Groups
In November 2020, data were retrieved from the Scandinavian Obesity Surgery Registry (SOReg), a nationwide registry described previously [5]. All patients operated with primary GBP or SG at 44 hospitals in Sweden between January 2007 and December 2017 were included in the study and were eligible for a 2-year follow-up. The study was approved by the Regional Ethics Committee (Dnr 2020 02268).
Indication Groups for Revisional Bariatric Surgery as Second-Line Treatment After Previous Bariatric Metabolic Surgery
Four different groups were defined according to the indication for revisional surgery as second-line treatment after previous GBP or SG. Groups I and II were based on frequently reported indications for revisional bariatric surgery, whereas the criteria for bariatric metabolic surgery according to the IFSO and ADA guidelines were applied in Groups III and IV.
Group I consisted of patients who had a percentage excess weight loss (%EWL) of less than 50% 2 years after their primary bariatric metabolic surgery [6, 7]. Group II comprised patients with increase in weight >10 kg after the nadir, also a frequently reported indication in the literature [7,8,9,10]. A prerequisite for weight calculations was attendance at both 1- and 2-year follow-ups. Patients who, after 2 years, still fulfilled the criteria for bariatric metabolic surgery according to the previous IFSO guidelines (BMI > 40 or a BMI 35–40 plus at least one associated medical problem) formed indication Group III [11]. According to the ADA guidelines, bariatric metabolic surgery should be considered in patients “who do not achieve durable weight loss and improvement in associated medical problems (including hyperglycemia) with nonsurgical methods.” Group IV comprised patients with BMI > 30 and pharmacologically treated type-2 diabetes (T2D) at the 2-year follow-up, thereby meeting the criteria for bariatric metabolic surgery as recommended in the ADA guidelines [12].
Associated Medical Problems
T2D was defined as a glycated hemoglobin A1c (HbA1c) ≥6.5%, fasting blood glucose ≥7 mmol/l, or treatment with antidiabetic medication. The definition of hypertension required ongoing medication. Treatment with continuous positive airway pressure (CPAP) indicated obstructive sleep apnea (OSA). Termination of antidiabetic medication in association with achievement of normal HbA1C and fasting glucose levels was defined as diabetes remission. Cessation of antihypertensive medication or CPAP treatment indicated remission of hypertension and OSA, respectively.
Data Collection
We collected and analyzed the following variables: age, gender, type of bariatric procedure, associated medical problems (T2D, hypertension, OSA), weight, and BMI. Weight and BMI results were measured as % excess weight loss (%EWL), with the calculation of ideal body weight as that equivalent to a BMI of 25 kg/m2 with excess BMI > 25 kg/m2 ((pre-op BMI − current BMI / pre-op BMI − 25) × 100) as well as % total weight loss (%TWL): ((pre-op weight − current weight / pre-op weight) × 100).
Statistical Analysis
Data were analyzed using SPSS version 26 (IBM, Armonk, NY). Continuous variables were analyzed using the unpaired Student’s 2-sample t test. The χ2 test was applied in the statistical analysis of categorical variables. The evaluation of predictors involved both univariate and multivariable logistic regression analysis. In the multivariable analysis, independent variables with more than ten events and p values < 0.1 were considered. The selection process for the multivariable analysis followed backward selection. The quality of the prediction model was assessed using the −2log likelihood measure. A significance level of p < 0.05 was set for both the baseline variables and the multivariable regression analysis.
Results
Baseline
A total of 60,426 patients were included in the study. Most patients had undergone GBP (n = 52,570), whereas SG was performed in 7856 individuals. None of the participants required revisional surgery during the study period. Table 1 (part A) displays demographics and patient-specific factors at baseline.
2-Year Follow-up
At the 2-year follow-up, patients in the GBP group had a significantly higher %EWL (83.7 ± 35.9 versus 73.2 ± 30.5, p < .001) and %TWL (32.3 ± 8.8 versus 25.6 ± 9.8, p < .001). Remission rates of OSA (77.6% versus 73.3%) and T2D (53.5% versus 50.9%) were equal. Hypertension resolved significantly more frequently in the GBP group (41.6% versus 34.8%, p < .001). Complete results of the 2-year follow-up are shown in Table 1 (part B).
Indications for Revisional Bariatric Metabolic Surgery as Second-Line Treatment
In Group I, a significantly higher proportion of patients who underwent SG qualified for surgical second-line treatment due to not achieving an EWL greater than 50% compared to GBP (23.0% versus 8.5%, p < .001). The results from both univariate and multivariate analyses are presented in Table 2(part A), with the latter showing that SG is a strong predictor for weight loss below 50% of excess weight (OR 4.46; 95% CI, 4.04–4.93; p < .001). Additionally, independent risk factors associated with meeting this criterion include BMI (OR 1.11; 95% CI, 1.10–1.12; p < .001), age (OR 1.24; 95% CI, 1.13–1.36; p < .001), male gender (OR 1.24; 95% CI, 1.13–1.36; p < .001), and T2D (OR 2.00; 95% CI, 1.82–2.19; p < .001).
In Group II, there were significantly more SG patients who experienced weight regain of at least 10 kg after reaching the lowest weight compared to GBP (4.3% versus 2.5%, p < .001). The multivariate regression model identified SG as the strongest predictor (OR 2.04; 95% CI, 1.67–2.48; p < .001). Similarly, BMI (OR 1.05; 95% CI, 1.04–1.07; p < .001), younger age (OR 1.03; 95% CI, 1.02–1.04; p < .001), and T2D (OR 1.54; 95% CI, 1.27–1.86; p < .001) were identified as independent risk factors for weight regain, as shown in Table 2 (part B).
At the 2-year follow-up, 8.0% of SG patients had a BMI > 40 or a BMI between 35 and 40 plus at least one associated medical problem, compared to 4.5% of the GBP patients (p < .001). These patients belonging to Group III thus continued to fulfill the previous IFSO guidelines criteria for bariatric metabolic surgery. In the univariate analysis of potential risk factors for being in Group III and in the multivariate regression model (Table 2, part C), SG emerged as the strongest predictor (OR 4.30; 95% CI, 3.60–5.12; p < .001).
Only 2% (equivalent to 639 patients) met the criteria to be included in Group IV. Within this group, 3 patients had de novo T2D. The likelihood of being categorized in this group was doubled for individuals who had undergone SG. However, the most influential risk factor was the presence of T2D at the time of the primary surgery. Additionally, the intensity of the treatment for T2D determined the odds of still meeting the ADA criteria: T2D with oral antidiabetic medication (OR 3.16; 95% CI, 2.53–3.95; p < .001), T2D with oral antidiabetic medication plus insulin (OR 7.00; 95% CI, 5.44–9.00; p < .001) and T2D with insulin (OR 8.39; 95% CI, 6.09–11.56; p < .001) (Table 2, part D).
Discussion
Three problems that have long plagued the bariatric surgery community: disagreement on outcomes, how weight loss should be calculated, and definition of the effect on associated medical problems. These have prevented meaningful evaluation and comparison of treatment results [13, 14]. In 2015, Brethauer et al. published “Standardized Outcomes Reporting in Metabolic and Bariatric Surgery” as an attempt “to provide guidance to authors and editors who write, review, and publish manuscripts focusing on bariatric and metabolic surgery.” This article contributed to improvements in the quality and comparability of reports on primary bariatric metabolic surgery. However, three aspects remained unanswered: 1. interpretation of results, 2. benchmarks for escalation of therapy, and 3. standardization of outcomes of second-line treatment. Weight loss has traditionally been labeled as “success,” “failure,” or “regain.” This terminology was questioned, and a more descriptive nomenclature proposed, i.e., primary responder (“success”), primary non-responder (“failure,” “weight loss failure,” or “insufficient weight loss”), and secondary non-responder (“weight regain”) that in turn has also been questioned [7, 15]. According to the results of a survey of 460 surgeons by Mahawar et al., most bariatric surgeons defined an EWL > 50% as a “successful response.” Specific criteria regarding the resolution of metabolic-associated medical problems were used by less than 50% of respondents. Definitions of “primary non-responders” or “secondary non-responders” were inconsistent [16]. These results are in line with several other publications [8, 9, 17]. Given the lack of consensus within the bariatric community regarding the evaluation and ranking of treatment outcomes, the decision to expand treatment through revisional surgery remains challenging. Consequently, the decision to escalate therapy is left to the discretion of the individual surgeon.
The aim of this study was to scrutinize the need for revisional bariatric metabolic surgery when applying four different indication categories: Group I, an EWL of less than 50%; Group II, regain of 10 kg or more in weight after reaching the nadir; Group III, application of IFSO guidelines’ criteria; and Group IV, application of ADA guidelines’ criteria. The indications in Groups I and II are frequently applied in the literature [7,8,9,10], and 12.1% of patients included in our study could be placed in one or other of these two indication groups. After adjustment for confounding factors, it was 4 times more likely for SG patients to fulfill these criteria for revisional bariatric surgery after 2 years compared to GBP patients.
It is unusual to utilize the IFSO or ADA guidelines’ criteria for revisional bariatric metabolic surgery. However, neither the IFSO nor the ADA recommendations is explicitly meant for primary bariatric metabolic surgery. Continuing to meet IFSO guidelines’ criteria has previously been applied by several authors [18,19,20]. Two years after bariatric metabolic surgery, 8.0% of SG patients had a BMI > 40 or a BMI 35–40 plus at least one associated medical problem (Group III) compared to 4.5% among the GBP patients. Prior to primary surgery, approximately 58% of the SG patients and about 84% of the GBP patients met the previous IFSO criteria. To our knowledge, the ADA guidelines’ criteria have not been applied as an indication for revisional bariatric metabolic surgery. A total of 2.0% of patients with a BMI > 30 and pharmacologically treated T2D 2 years after SG or GBP formed Group IV in this study. SG patients had a twofold higher probability of being in Group IV compared to GBP. In the present study, the rates of T2D remission were in line with the results published in a systematic review and meta-analysis of randomized trials comparing SG and GBP [21]. One predictive factor for continuing to meet the ADA criteria for bariatric metabolic surgery after primary surgery is diabetes treatment that depends on insulin. It is well known that low intensity diabetes treatment, short duration of T2D, and satisfactory glucose control are decisive factors for the probability of diabetes resolution after bariatric metabolic surgery [22,23,24].
Regardless of the criteria used to identify patients requiring revisional bariatric surgery, SG was clearly a risk factor for weight non-response. This can be interpreted as indirect confirmation of the results of two randomized trials [25, 26]. We had no intention to question SG as a technique per se nor was our intention to develop a risk model for the need for revisional surgery, identify contributing risk factors for non-response, or present improvement suggestions regarding patient selection and surgical techniques. The idea was simply to pose the question: how significant is the theoretical need for revisional bariatric metabolic surgery after previous SG or GBP if we adhere to certain criteria?
Considering the resources available in Sweden, it is not practical to offer revisional bariatric metabolic surgery to all patients identified within the four indication groups mentioned in this study. The management of obesity should consistently recognize its chronic nature, necessitating long-term care. Ensuring universal access to treatment, regardless of the chosen approach, is of importance. To tackle this challenge, a roadmap should encompass key action points: establishing agreement on treatment benchmarks, developing evaluation tools for result interpretation, and assessing alternative non-surgical treatment strategies. The responsibility lies with the bariatric community to establish a consensus on indications for revisional bariatric surgery, while simultaneously allowing for individual assessments and deviations from the established guidelines. It is frequently observed that patients who potentially meet the criteria for revisional bariatric metabolic surgery 2 years after their primary procedure report satisfaction with the favorable outcomes, including the resolution of OSA, successful childbirth, improved quality of life, and alleviation of back pain. The intended outcomes of primary bariatric metabolic surgery must be well-defined and crystal clear, otherwise critical evaluation of individual results is impossible. Multidisciplinary assessment of all patients before primary and secondary interventions is highly desirable [27, 28]. Proactive interdisciplinary follow-up is fundamental to identify primary and secondary non-responders [29]. Courcoulas et al. demonstrated an association between the “magnitude and direction/slope of the initial loss” and long-term weight trajectories, stressing the importance of “enhanced and early (Years 1-2) postoperative efforts to optimize short-term weight loss trajectory directions” [30]. The sooner secondary treatment is initiated, the better the results in the long run. Similarly, the results of a study by Brissman et al. suggest the importance of early reintervention, showing that percentage weight loss during the first postoperative year was predictive of “surgical treatment failure 5 years after surgery” [31]. Adjuvant pharmacological therapy in the early period after bariatric metabolic surgery may enhance treatment results [32,33,34]. Compared to primary surgery, the risk for perioperative complications is higher in revisional surgery [4]. Non-surgical treatment options should be thoroughly evaluated and should be considered when deciding on reintervention or therapy escalation [29]. The major challenge is to establish a robust scientific foundation for the solution of this complex problem. It is well established that patients with advanced obesity and associated medical problems do not benefit as much from changes in lifestyle or intensive medical therapies compared to the benefits of primary bariatric metabolic surgery. It appears that this is not directly applicable to secondary treatment approaches. The superiority of revisional bariatric surgery over non-surgical interventions has not been confirmed. Randomized trials studying second-line treatment of obesity and related diseases are lacking despite the number of patients concerned.
Limitation
The study had a retrospective design and used registry data, which comes with certain limitations. Furthermore, there is a lack of agreement among bariatric surgeons regarding the criteria for revisional bariatric surgery or other second-line treatments. Nevertheless, we performed this study specifically to address this issue and do not consider it a limitation. We acknowledge that applying the new IFSO guidelines, which were published in autumn 2022, to our study would have led to even more patients being eligible for second-line treatment.
Conclusion
This study focused on the need for revisional bariatric metabolic surgery using four indication categories. SG patients were more likely to require revisional surgery compared to GBP patients. Limited resources make it impractical to offer revisional surgery to all eligible patients. Key actions include establishing treatment benchmarks and evaluating non-surgical treatment options.
References
Brethauer SA, Kothari S, Sudan R, et al. Systematic review on reoperative bariatric surgery: American Society for Metabolic and Bariatric Surgery Revision Task Force. Surg Obes Relat Dis. 2014;10(5):952–72.
Radtka 3rd JF, Puleo FJ, Wang L, et al. Revisional bariatric surgery: who, what, where, and when? Surg Obes Relat Dis. 2010;6(6):635–42.
Axer S, Szabo E, Naslund I. Weight loss and alterations in co-morbidities after revisional gastric bypass: a case-matched study from the Scandinavian Obesity Surgery Registry. Surg Obes Relat Dis. 2017;13(5):796–800.
Axer S, Szabo E, Agerskov S, et al. Predictive factors of complications in revisional gastric bypass surgery: results from the Scandinavian Obesity Surgery Registry. Surg Obes Relat Dis. 2019;15(12):2094–100.
Hedenbro JL, Naslund E, Boman L, et al. Formation of the Scandinavian Obesity Surgery Registry. SOReg Obes Surg. 2015;25(10):1893–900.
van de Laar A, de Caluwe L, Dillemans B. Relative outcome measures for bariatric surgery. Evidence against excess weight loss and excess body mass index loss from a series of laparoscopic Roux-en-Y gastric bypass patients. Obes Surg. 2011;21(6):763–7.
Bonouvrie DS, Uittenbogaart M, Luijten A, et al. Lack of standard definitions of primary and secondary (non) responders after primary gastric bypass and gastric sleeve: a systematic review. Obes Surg. 2019;29(2):691–7.
Lauti M, Kularatna M, Hill AG, et al. Weight regain following sleeve gastrectomy-a systematic review. Obes Surg. 2016;26(6):1326–34.
Nedelcu M, Khwaja HA, Rogula TG. Weight regain after bariatric surgery-how should it be defined? Surg Obes Relat Dis. 2016;12(5):1129–30.
Mann JP, Jakes AD, Hayden JD, et al. Systematic review of definitions of failure in revisional bariatric surgery. Obes Surg. 2015;25(3):571–4.
Di Lorenzo N, Antoniou SA, Batterham RL, et al. Clinical practice guidelines of the European Association for Endoscopic Surgery (EAES) on bariatric surgery: update 2020 endorsed by IFSO-EC, EASO and ESPCOP. Surg Endosc. 2020;34(6):2332–58.
American Diabetes A.8. Obesity management for the treatment of type 2 diabetes: standards of medical care in diabetes-2021. Diabetes Care. 2021;44(Suppl 1):S100–S10.
Hopkins JC, Howes N, Chalmers K, et al. Outcome reporting in bariatric surgery: an in-depth analysis to inform the development of a core outcome set, the BARIACT study. Obes Rev. 2015;16(1):88–106.
Montero PN, Stefanidis D, Norton HJ, et al. Reported excess weight loss after bariatric surgery could vary significantly depending on calculation method: a plea for standardization. Surg Obes Relat Dis. 2011;7(4):531–4.
Mahawar KK. Measuring and defining response and no-response after bariatric surgery. Obes Surg. 2019;29(5):1649–50.
Mahawar KK, Nimeri A, Adamo M, et al. Practices concerning revisional bariatric surgery: a survey of 460 surgeons. Obes Surg. 2018;28(9):2650–60.
Lauti M, Lemanu D, Zeng ISL, et al. Definition determines weight regain outcomes after sleeve gastrectomy. Surg Obes Relat Dis. 2017;13(7):1123–9.
Pizza F, D'Antonio D, Carbonell Asins JA, et al. One anastomosis gastric bypass after sleeve gastrectomy failure: does a single procedure fit for all? Obes Surg. 2021;31(4):1722–32.
Homan J, Betzel B, Aarts EO, et al. Secondary surgery after sleeve gastrectomy: Roux-en-Y gastric bypass or biliopancreatic diversion with duodenal switch. Surg Obes Relat Dis. 2015;11(4):771–7.
Dijkhorst PJ, Boerboom AB, Janssen IMC, et al. Failed sleeve gastrectomy: single anastomosis duodenoileal bypass or Roux-en-Y gastric bypass? A multicenter cohort study. Obes Surg. 2018;28(12):3834–42.
Borgeraas H, Hofso D, Hertel JK, et al. Comparison of the effect of Roux-en-Y gastric bypass and sleeve gastrectomy on remission of type 2 diabetes: a systematic review and meta-analysis of randomized controlled trials. Obes Rev. 2020;21(6):e13011.
Dang JT, Sheppard C, Kim D, et al. Predictive factors for diabetes remission after bariatric surgery. Can J Surg. 2019;62(5):315–9.
Schauer PR, Bhatt DL, Kirwan JP, et al. Bariatric surgery versus intensive medical therapy for diabetes - 5-year outcomes. N Engl J Med. 2017;376(7):641–51.
Stenberg E, Olbers T, Cao Y, et al. Factors determining chance of type 2 diabetes remission after Roux-en-Y gastric bypass surgery: a nationwide cohort study in 8057 Swedish patients. BMJ Open Diabetes Res Care. 2021;9(1)
Salminen P, Helmio M, Ovaska J, et al. Effect of laparoscopic sleeve gastrectomy vs laparoscopic Roux-en-Y gastric bypass on weight loss at 5 years among patients with morbid obesity: the SLEEVEPASS randomized clinical trial. JAMA. 2018;319(3):241–54.
Peterli R, Wolnerhanssen BK, Peters T, et al. Effect of laparoscopic sleeve gastrectomy vs laparoscopic Roux-en-Y gastric bypass on weight loss in patients with morbid obesity: the SM-BOSS randomized clinical trial. JAMA. 2018;319(3):255–65.
Obesity: identification, assessment and management: National Institute for Health and Care Excellence; 2014. Available from: https://www.nice.org.uk/guidance/cg189/chapter/Introduction. Accessed 4 Apr 2023.
Bullen NL, Parmar J, Gilbert J, et al. How effective is the multidisciplinary team approach in bariatric surgery? Obes Surg. 2019;29(10):3232–8.
Cambi MPC, Baretta GAP, Magro DO, et al. Multidisciplinary approach for weight regain-how to manage this challenging condition: an expert review. Obes Surg. 2021;31(3):1290–303.
Courcoulas AP, King WC, Belle SH, et al. Seven-year weight trajectories and health outcomes in the longitudinal assessment of bariatric surgery (LABS) study. JAMA Surg. 2018;153(5):427–34.
Brissman M, Beamish AJ, Olbers T, et al. Prevalence of insufficient weight loss 5 years after Roux-en-Y gastric bypass: metabolic consequences and prediction estimates: a prospective registry study. BMJ Open. 2021;11(3):e046407.
Stanford FC, Alfaris N, Gomez G, et al. The utility of weight loss medications after bariatric surgery for weight regain or inadequate weight loss: a multi-center study. Surg Obes Relat Dis. 2017;13(3):491–500.
Srivastava G, Buffington C. A specialized medical management program to address post-operative weight regain in bariatric patients. Obes Surg. 2018;28(8):2241–6.
Nor Hanipah Z, Nasr EC, Bucak E, et al. Efficacy of adjuvant weight loss medication after bariatric surgery. Surg Obes Relat Dis. 2018;14(1):93–8.
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For this type of study, formal consent is not required. The study was approved by the Regional Ethics Committee (Dnr 2020 02268).
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Key points
Bariatric surgery challenges: 1. defining success; 2. establishing benchmarks for second-line treatment.
Approximately 13% may require revisional surgery after 2 years due to weight and metabolic non-response.
SG (26%) outperforms GBP (11%) in meeting at least one of four revisional surgery criteria.
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Axer, S., Szabo, E. & Näslund, I. Non-response After Gastric Bypass and Sleeve Gastrectomy—the Theoretical Need for Revisional Bariatric Surgery: Results from the Scandinavian Obesity Surgery Registry. OBES SURG 33, 2973–2980 (2023). https://doi.org/10.1007/s11695-023-06783-0
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DOI: https://doi.org/10.1007/s11695-023-06783-0