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The Preoperative Dietary Inflammatory Index Predicts Changes in Cardiometabolic Risk Factors After 12 Months of Roux-en-Y Gastric Bypass

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Abstract

Background

The objective of this study was to evaluate Dietary Inflammatory Index (DII®) in the preoperative period as well as 3 and 12 months post-surgery and its association with cardiometabolic risk factors after RYGB.

Materials and Methods

This is a prospective cohort study of 50 patients (both sexes) who underwent RYGB. All data were collected in 3 phases: before surgery, 3, and 12 months post-surgery. To calculate DII scores, we utilized mean nutrients from three 24-h recalls at each time point.

Results

The patients had median age of 39.1 ± 7.9 years (70% women). Mean preoperative DII® score of 0.39 ± 1.49 was slightly pro-inflammatory. Mean DII score reduced to − 1.52 ± 1.27 after 3 months post-surgery and was classified anti-inflammatory. This value rebounded to − 0.88 ± 1.49 at 12 months but was still anti-inflammatory. From the adjusted linear regression analysis, we observed that preoperative DII score was statistically associated with variations in neck circumference (β = − 0.50; p = 0.03), waist-hip ratio (β = 0.01; p = 0.02), total cholesterol (β = 6.47; p = 0.002), and LDL cholesterol (β = 6.42; p = 0.001) after 12 months post-surgery. Changes in DII® at 3 and 12 months were not associated with changes in cardiometabolic risk factors.

Conclusion

We observe significant changes in the inflammation potential of diet after 3 and 12 months of RYGB. Patients with higher preoperative E-DII scores have a greater metabolic improvement after 12 months of surgery.

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Acknowledgments

To the Coordination for the Improvement of Personnel at the - CAPES for the financing of the project

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Authors and Affiliations

  1. Nutrition Course of the Federal University of Tocantins/TO, Federal University of Viçosa, Quadra 109 North, NS-15, ALCNO-14, Plano Diretor Norte, Palmas, Tocantins, 77001-090, Brazil

    Sônia L Pinto

  2. Department of Nutrition and Health, Federal University of Viçosa/MG, University Campus, Viçosa, Minas Gerais, 36570-900, Brazil

    Sônia L Pinto, Leidjaira L Juvanhol, Alessandra da Silva & Josefina Bressan

  3. Cancer Prevention and Control Program, University of South Carolina, Columbia, SC, 29208, USA

    Nitin Shivappa & James R Hébert

  4. Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, 29208, USA

    Nitin Shivappa & James R Hébert

  5. Connecting Health Innovations LLC, Columbia, SC, 29201, USA

    Nitin Shivappa & James R Hébert

Authors
  1. Sônia L Pinto
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  2. Leidjaira L Juvanhol
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  3. Alessandra da Silva
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  4. Nitin Shivappa
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  5. James R Hébert
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  6. Josefina Bressan
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Contributions

Sônia L Pinto contributed in the design of the study, data collection, analysis and interpretation, manuscript writing, and final version approval. Sônia L Pinto, Leidjaira L Juvanhol, Alessandra da Silva, and Josefina Bressan contributed in the design of the study, analysis and interpretation of the data, critical revision of the manuscript, and approval of the final version. Nitin Shivappa and James R Hébert contributed in analysis and interpretation of the data, critical revision of the manuscript, and approval of the final version.

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Correspondence to Sônia L Pinto.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Pinto, S.L., Juvanhol, L.L., da Silva, A. et al. The Preoperative Dietary Inflammatory Index Predicts Changes in Cardiometabolic Risk Factors After 12 Months of Roux-en-Y Gastric Bypass. OBES SURG 30, 3932–3939 (2020). https://doi.org/10.1007/s11695-020-04756-1

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  • DOI: https://doi.org/10.1007/s11695-020-04756-1

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