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Emerging botanical processing technology of bioflavonoid for sustainable production of high value standardized nutraceutical ingredients: a review

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Abstract

Herbal standardization is a crucial aspect in the field of herbal medicine and nutraceutical products. It refers to the process of developing and implementing standards to ensure the consistency, quality, and efficacy of herbal products. One important class of bioactive compounds that is widely distributed in plants is bioflavonoids, natural polyphenolic compounds. The significant pharmacological properties of bioflavonoids include antioxidant, anti-inflammatory, anti-diabetic, anti-aging and antimicrobial properties are promising therapeutic nutraceutical agents in the management of several acute and chronic diseases. However, the exploitation of these bioflavonoids demands systematic standardization approaches covering from extraction to enrichment of high-quality standardized multicomponent botanical extract in order to meet the desired efficacy. Hence, this review describes on the plant innovative processing technologies comprising of drying, solvent, extraction technique and adsorbent technologies accompanied with the established quality control methods using high end analytical instrument and omics technology. The importance of bioactive compound standardization and global demand of flavonoid in various applications are also highlighted.

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Abbreviations

COS:

Conventional Organic Solvent

NaDES:

Natural Deep Eutectic Solvent

HBD:

Hydrogen Bond Donor

HBA:

Hydrogen Bond Acceptor

MAR:

Macroporous resin

UAE:

Ultrasonic: Assisted Extraction

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The author would like to acknowledge Universiti Sains Malaysia for financial support through USM Short Term Grant (Grant number: 304/PTEKIND/6315802).

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  1. Bioresource Technology Division, School of Industrial Technology, Universiti Sains Malaysia, Gelugor, Penang, 11800, Malaysia

    Mohamad Shazeli Che Zain

  2. Renewable Biomass Transformation Cluster, School of Industrial Technology, Universiti Sains Malaysia, Gelugor, Penang, 11800, Malaysia

    Mohamad Shazeli Che Zain

  3. Phytochemistry and Phytotechnology Research Group (PhytoRG), Universiti Sains Malaysia, Gelugor, Penang, 11800, Malaysia

    Mohamad Shazeli Che Zain

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Che Zain, M.S. Emerging botanical processing technology of bioflavonoid for sustainable production of high value standardized nutraceutical ingredients: a review. Food Measure (2024). https://doi.org/10.1007/s11694-024-02591-x

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