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Optimization of microwave-assisted solvent extraction of hemp (Cannabis sativa L.) seed oil using RSM: evaluation of oil quality

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Abstract

In this study, the effect of solvent ratio of hexane to isopropanol (0:100, 50:50, and 100:0 v/v%), microwave power (180, 540, and 900 W) and extraction time (1, 2.5, and 4 min) were investigated on the oil extraction efficiency, total phenol content, DPPH radical scavenging, peroxide value and oil color index. Extraction conditions were optimized by response surface methodology and Box–Behnken Design. The optimal conditions were obtained as hexane-to-isopropanol ratio of approximately 3:2, microwave power of 450 W and the extraction time of 1 min. Then, the hemp seed oil was extracted under the optimal conditions. The optimal predicted contents for oil yield (26.34%), total phenolics (3.85 mg GA/g oil), DPPH inhibition (74.29%), peroxide (3.94 meq/kg) and Color index (58.13) were agreed with the predicted conditions because the Resident standard error (RSE) values were less than 5%.

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Acknowledgements

We are grateful to Sari Agricultural Sciences and Natural Resources University (SANRU) for financial support under Project No. 02-1398-07.

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Authors and Affiliations

  1. Director of Research and Development of Kowsar Agro-Industry Company, Ramsar, Mazandaran, Iran

    Donya Rahim Soroush

  2. Departemnt of Food Science and Technology Research, Food and Drug Administration (FDA), Kermanshah University of Medical Sciences, Kermanshah, Iran

    Somaye Solaimanimehr

  3. Department of Food Hygiene, Faculty of Veterinary Medicine, Amol University of Special Modern Technologies, Aftab 24 St., Haraz Av., Amol, Iran

    Maryam Azizkhani

  4. Department of Food Science and Technology, Sari Agricultural Sciences and Natural Resources University, Khazar Abad Road, PO Box 578, Sari, Iran

    Reza Esmaeilzadeh Kenari & Bahareh Dehghan

  5. Department of Pharmaceutics, School of Pharmacy, Kermanshah University of Medical Sciences, Kermanshah, Iran

    Ghobad Mohammadi

  6. Department of Food Science and Technology, Faculty of Nutrition and Food Technology, Kermanshah University of Medical Sciences, Kermanshah, Iran

    Ehsan Sadeghi

Authors
  1. Donya Rahim Soroush
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  2. Somaye Solaimanimehr
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  3. Maryam Azizkhani
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  4. Reza Esmaeilzadeh Kenari
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  5. Bahareh Dehghan
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  7. Ehsan Sadeghi
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Correspondence to Maryam Azizkhani.

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Soroush, D.R., Solaimanimehr, S., Azizkhani, M. et al. Optimization of microwave-assisted solvent extraction of hemp (Cannabis sativa L.) seed oil using RSM: evaluation of oil quality. Food Measure 15, 5191–5202 (2021). https://doi.org/10.1007/s11694-021-01087-2

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  • DOI: https://doi.org/10.1007/s11694-021-01087-2

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