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Establishment and characterization of androgen-independent human prostate cancer cell lines, PcBra1, PcBra2, and PcBra3

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Abstract

One of the main obstacles for understanding biological events involved in cancer is the lack of experimental models for in vitro studies especially for prostate cancer (PC).There are a limited number of PC cell lines being the majority originated from metastatic tumors mostly acquired from American Tissue Cell Culture which demands importation an expensive and bureaucratic process. Also it is well known that there are ethnic differences between populations concerning the behavior of tumors and the research based on cell lines derived from Brazilians should be interesting. Our aim was to develop tumor cell lines from primary PC.

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Authors and Affiliations

  1. Laboratory of Medical Investigation, Urology Department–LIM55, Medical School, São Paulo University, Av. Dr. Arnaldo 455, Room 2145, 01246-903, São Paulo, Brazil

    Camila B. Piantino, Miguel Srougi & Katia R. M. Leite

  2. Genoa Biotechnology, Desembargador Eliseu Guilherme 69, 04004-030, São Paulo, Brazil

    Juliana M. Sousa-Canavez, Luiz Heraldo Camara-Lopes & Katia R. M. Leite

  3. Laboratory of Medical Investigation, Liver Transplantation and Surgery Unit, Department of Gastroenterology–LIM14, Medical School, São Paolo University, Av. Dr. Arnaldo 455, 01246-903, São Paulo, Brazil

    Marta Bellodi-Privato

  4. Laboratory of Medical Investigation, Department of Legal Medicine, Ethics and Occupational Health, Medical School, São Paulo University, São Paulo, SP, Brazil

    Gilka Jorge Figaro Gattás, Fernanda de Toledo Gonçalves & Cintia Fridman

Authors
  1. Camila B. Piantino
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  2. Juliana M. Sousa-Canavez
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  3. Marta Bellodi-Privato
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  4. Miguel Srougi
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  5. Luiz Heraldo Camara-Lopes
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  6. Gilka Jorge Figaro Gattás
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  7. Fernanda de Toledo Gonçalves
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  8. Cintia Fridman
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  9. Katia R. M. Leite
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Corresponding author

Correspondence to Katia R. M. Leite.

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Editor: J. Denry Sato

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Piantino, C.B., Sousa-Canavez, J.M., Bellodi-Privato, M. et al. Establishment and characterization of androgen-independent human prostate cancer cell lines, PcBra1, PcBra2, and PcBra3. In Vitro Cell.Dev.Biol.-Animal 46, 123–130 (2010). https://doi.org/10.1007/s11626-009-9249-7

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  • DOI: https://doi.org/10.1007/s11626-009-9249-7

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