Skip to main content
Log in

Transcervical Heller Myotomy Using Flexible Endoscopy

  • Original Article
  • Published:
Journal of Gastrointestinal Surgery Aims and scope

Abstract

Introduction

Esophageal achalasia is most commonly treated by laparoscopic myotomy. Transesophageal approaches using flexible endoscopy have recently been described. We hypothesized that using techniques and flexible instruments from our NOTES experience through a small cervical incision would be a safer and less traumatic route for esophageal myotomy. The purpose of this study was to evaluate the feasibility, safety, and success rate of using flexible endoscopes to perform anterior or posterior Heller myotomy via a transcervical approach.

Methods

This animal (porcine) and human cadaver study was conducted at the Legacy Research and Technology Center. Mediastinal operations on ten live, anesthetized pigs and two human cadavers were performed using standard flexible endoscopes through a small incision at the supra-sternal notch. The esophagus was dissected to the phreno-esophageal junction using balloon dilatation in the peri-esophageal space followed by either anterior or posterior distal esophageal myotomy. Success rate was recorded of esophageal dissection to the diaphragm and proximal stomach, anterior and posterior myotomy, perforation, and complication rates.

Results

Dissection of the esophagus to the diaphragm and performing esophageal myotomy was achieved in 100% of attempts. Posterior Heller myotomy was always extendable onto the gastric wall, while anterior gastric extension of the myotomy was found to be more difficult (4/4 and 2/8, respectively; P = 0.061).

Conclusion

Heller myotomy through a small cervical incision using flexible endoscopes is feasible. A complete Heller myotomy was performed with a higher success rate posteriorly possibly due to less anatomic interference.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6

Similar content being viewed by others

References

  1. Allemann P, Perretta S, Asakuma M, Dallemagne B, Mutter D, Marescaux J. Multimedia manuscript. NOTES retroperitoneal transvaginal distal pancreatectomy. Surg Endosc 2009;23(4):882–3.

    Article  PubMed  Google Scholar 

  2. Nassif J, Zacharopoulou C, Marescaux J, Wattiez A. Transvaginal extraperitoneal lymphadenectomy by Natural Orifices Transluminal Endoscopic Surgery (NOTES) technique in porcine model: feasibility and survival study. Gynecol Oncol 2009;112(2):405–8.

    Article  PubMed  Google Scholar 

  3. Perretta S, Allemann P, Dallemagne B, Marescaux J. Natural Orifice Transluminal Orifice Surgery (NOTES) for neoplasia of the chest and mediastinum. Surg Oncol 2009 Jun;18(2):177–80.

    Article  CAS  PubMed  Google Scholar 

  4. Zacharopoulou C, Nassif J, Allemann P, Dallemagne B, Perretta S, Marescaux J, Wattiez A. Exploration of the retroperitoneum using the transvaginal natural orifice transluminal endoscopic surgery technique. J Minim Invasive Gynecol 2009;16(2):198–203.

    Article  PubMed  Google Scholar 

  5. Fritscher-Ravens A, Patel K, Ghanbari A, Kahle E, von Herbay A, Fritscher T, Niemann H, Koehler P. Natural orifice transluminal endoscopic surgery (NOTES) in the mediastinum: long-term survival animal experiments in transesophageal access, including minor surgical procedures. Endoscopy 2007;39(10):870–5.

    Article  CAS  PubMed  Google Scholar 

  6. Pasricha PJ, Hawari R, Ahmed I, Chen J, Cotton PB, Hawes RH, Kalloo AN, Kantsevoy SV, Gostout CJ. Submucosal endoscopic esophageal myotomy: a novel experimental approach for the treatment of achalasia. Endoscopy 2007;39(9):761–4.

    Article  CAS  PubMed  Google Scholar 

  7. Daniels AC. A method of biopsy useful in diagnosing certain intrathoracic diseases. Dis Chest 1949;16(3):360–7.

    Article  CAS  PubMed  Google Scholar 

  8. Sumiyama K, Gostout CJ, Rajan E, Bakken TA, Knipschield MA, Chung S, Cotton PB, Hawes RH, Kalloo AN, Kantsevoy SV, Pasricha PJ. Pilot study of transesophageal endoscopic epicardial coagulation by submucosal endoscopy with the mucosal flap safety valve technique (with videos). Gastrointest Endosc 2008;67(3):497–501.

    Article  PubMed  Google Scholar 

  9. Willingham FF, Gee DW, Lauwers GY, Brugge WR, Rattner DW. Natural orifice transesophageal mediastinoscopy and thoracoscopy. Surg Endosc 2008;22(4):1042–7.

    Article  CAS  PubMed  Google Scholar 

  10. Inoue H, Minami H, Kobayashi Y, Sato Y, Kaga M, Suzuki M, Satodate H, Ogaka N, Itoh H, Kudo S. Peroral endoscopic myotomy (POEM) for esophageal achalasia. Endoscopy. 2010 Apr;42(4):265–71.

    Article  CAS  PubMed  Google Scholar 

  11. Leschber G, Sperling D, Klemm W, Merk J. Does video-mediastinoscopy improve the results of conventional mediastinoscopy? Eur J Cardiothorac Surg 2008;33(2):289–93.

    Article  PubMed  Google Scholar 

  12. Spaun GO, Swanstrom LL. Quo vadis NOTES. European Surgery 2008;40(5):211–9.

    Article  Google Scholar 

  13. Carlens E. Mediastinoscopy: a method for inspection and tissue biopsy in the superior mediastinum. Dis Chest 1959;36:343–52.

    CAS  PubMed  Google Scholar 

  14. Kipfmuller K, Duda D, Kessler S, Melzer A, Buess G. [Endoscopic microsurgical dissection of the esophagus: a contribution to the reduction of pulmonary complications following esophageal resection? A comparative animal experiment study]. Langenbecks Arch Chir 1990;375(1):11–8.

    Article  CAS  PubMed  Google Scholar 

  15. Buess G, Becker HD (1990) Minimally invasive surgery in tumors of the esophagus. Langenbecks Arch Chir Suppl II Verh Dtsch Ges Chir 1990:1355–60.

    Google Scholar 

  16. Buess G, Becker HD, Mentges B, Teichmann R, Lenz G. [Endoscopic microsurgery dissection of the esophagus. II. Initial clinical experiences with demonstration of the surgical technic]. Chirurg 1990;61(4):308–11.

    CAS  PubMed  Google Scholar 

  17. Bonavina L, Incarbone R, Bona D, Peracchia A. Esophagectomy via laparoscopy and transmediastinal endodissection. J Laparoendosc Adv Surg Tech A 2004;14(1):13–6.

    Article  PubMed  Google Scholar 

  18. Kuzdzal J, Zielinski M, Papla B, Urbanik A, Wojciechowski W, Narski M, Szlubowski A, Hauer L. The transcervical extended mediastinal lymphadenectomy versus cervical mediastinoscopy in non-small cell lung cancer staging. Eur J Cardiothorac Surg 2007;31(1):88–94.

    Article  PubMed  Google Scholar 

  19. Spaun GO, Zheng B, Martinec DV, Cassera MA, Dunst CM, Swanstrom LL. Bimanual coordination in natural orifice transluminal endoscopic surgery: comparing the conventional dual-channel endoscope, the R-Scope, and a novel direct-drive system. Gastrointest Endosc 2009;69(6):e39–45.

    Article  PubMed  Google Scholar 

  20. Spaun GO, Zheng B, Swanstrom LL. A multitasking platform for natural orifice translumenal endoscopic surgery (NOTES): a benchtop comparison of a new device for flexible endoscopic surgery and a standard dual-channel endoscope. Surg Endosc 2009;23(12):2720–27.

    Google Scholar 

  21. Heller E. Extramukoese Cardiaplastik beim chronischen Cardiospasmus mit Dilatation des Oesophagus Mittheil. a. d, Grenzgeb. d. Med. u. Chir. 1914(Bd. xxvii):S. 141.

  22. Fritscher-Ravens A, Cuming T, Jacobsen B, Seehusen F, Ghanbari A, Kahle E, von Herbay A, Koehler P, Milla P. Feasibility and safety of endoscopic full-thickness esophageal wall resection and defect closure: a prospective long-term survival animal study. Gastrointest Endosc 2009;69(7):1314–20.

    Article  PubMed  Google Scholar 

  23. Gee DW, Willingham FF, Lauwers GY, Brugge WR, Rattner DW. Natural orifice transesophageal mediastinoscopy and thoracoscopy: a survival series in swine. Surg Endosc 2008;22(10):2117–22.

    Article  PubMed  Google Scholar 

  24. Lee SL, Lerotic M, Vitiello V, Giannarou S, Kwok KW, Visentini-Scarzanella M, Yang GZ. From medical images to minimally invasive intervention: Computer assistance for robotic surgery. Comput Med Imaging Graph 2010 Jan;34(1):33–45.

    Article  PubMed  Google Scholar 

  25. Bichlmeier C, Heining SM, Feuerstein M, Navab N. The virtual mirror: a new interaction paradigm for augmented reality environments. IEEE Trans Med Imaging 2009;28(9):1498–510.

    Article  PubMed  Google Scholar 

Download references

Acknowledgment

The authors thank the Natural Orifice Surgery Consortium for Assessment and Research (NOSCAR). This study was supported in part by a 2008 research grant from NOSCAR.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Georg O. Spaun.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Spaun, G.O., Dunst, C.M., Arnold, B.N. et al. Transcervical Heller Myotomy Using Flexible Endoscopy. J Gastrointest Surg 14, 1902–1909 (2010). https://doi.org/10.1007/s11605-010-1290-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11605-010-1290-z

Keywords

Navigation