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The physiological accumulation of FDG in the muscles in relation to the side of intravenous administration

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Abstract

Purpose

The purpose of the study was to evaluate the physiological accumulation of 18F-FDG in the muscles in relation to the side of intravenous administration.

Materials and methods

We retrospectively investigated 3,118 18F-FDG-PET/CT examinations. We evaluated the physiological accumulation of FDG in the muscles of the shoulder and arm relative to its dependence on the side of intravenous administration.

Results

Six hundred six of the 3,118 examinations (19.4%) showed physiological accumulation of FDG in the teres minor muscle. Accumulation was seen on the side of administration in 486 examinations (80.2%), contralateral to the side of administration in 56 examinations (9.2%), and bilaterally in 64 examinations (10.6%). Five hundred seventy-seven of the 3,118 examinations (18.5%) showed accumulation of FDG in the muscles between the radioulna near the elbow. Accumulation was observed on the side of administration in 432 examinations (74.9%), contralateral to the side of the administration in 71 examinations (12.3%), and bilaterally in 74 examinations (12.8%).

Conclusion

The present study finds that not only accumulation in the teres minor muscles but also accumulation in the muscles between the radioulna near the elbow occurs significantly more frequently on the side of intravenous administration compared to the contralateral side.

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References

  1. Engel H, Steinert H, Buck A, Berthold T, Huch Böni RA, von Schulthess GK. Whole-body PET: physiological and artifactual fluorodeoxyglucose accumulations. J Nucl Med. 1996;37:441–6.

    CAS  PubMed  Google Scholar 

  2. Jackson RS, Schlarman TC, Hubble WL, Osman MM. Prevalence and patterns of physiologic muscle uptake detected with whole-body 18F-FDG PET. J Nucl Med Technol. 2006;34:29–33.

    PubMed  Google Scholar 

  3. Tashiro M, Fujimoto T, Itoh M, Kubota K, Fujiwara T, Miyake M, et al. 18F-FDG PET imaging of muscle activity in runners. J Nucl Med. 1999;40:70–6.

    CAS  PubMed  Google Scholar 

  4. Cook GJ, Fogelman I, Maisey MN. Normal physiological and benign pathological variants of 18-fluoro-2-deoxyglucose positron-emission tomography scanning: potential for error in interpretation. Semin Nucl Med. 1996;26:308–14.

    Article  CAS  PubMed  Google Scholar 

  5. Kostakoglu L, Wong JC, Barrington SF, Cronin BF, Dynes AM, Maisey MN. Speech-related visualization of laryngeal muscles with fluorine-18-FDG. J Nucl Med. 1996;37:1771–3.

    CAS  PubMed  Google Scholar 

  6. Kelley DE, Williams KV, Price JC. Insulin regulation of glucose transport and phosphorylation in skeletal muscle assessed by PET. Am J Physiol. 1999;277:E361–9.

    CAS  PubMed  Google Scholar 

  7. Nuutila P, Knuuti MJ, Mäki M, Laine H, Ruotsalainen U, Teräs M, et al. Gender and insulin sensitivity in the heart and in skeletal muscles. Studies using positron emission tomography. Diabetes. 1995;44:31–6.

    Article  CAS  PubMed  Google Scholar 

  8. Schwartz P Jr, Pinaquy JB. Unilateral forearm muscle 18F-FDG uptake after using a smartphone. Clin Nucl Med. 2015;40:e532–3.

    Article  PubMed  Google Scholar 

  9. Tateyama M, Fujihara K, Misu T, Arai A, Kaneta T, Aoki M. Clinical values of FDG PET in polymyositis and dermatomyositis syndromes: imaging of skeletal muscle inflammation. BMJ Open. 2015;5:e006763.

    Article  PubMed  PubMed Central  Google Scholar 

  10. Tanaka S, Ikeda K, Uchiyama K, Iwamoto T, Sanayama Y, Okubo A, et al. [18F]FDG uptake in proximal muscles assessed by PET/CT reflects both global and local muscular inflammation and provides useful information in the management of patients with polymyositis/dermatomyositis. Rheumatology (Oxford). 2013;52:1271–8.

    Article  CAS  Google Scholar 

  11. Han EJ, Jang YS, Lee IS, Lee JM, Kang S, Kim HS. Muscular sarcoidosis detected by F-18 FDG PET/CT in a hypercalcemic patient. J Korean Med Sci. 2013;28:1399–402.

    Article  PubMed  PubMed Central  Google Scholar 

  12. Marie I, Lahaxe L, Vera P, Edet-Samson A. Follow-up of muscular sarcoidosis using fluorodeoxyglucose positron emission tomography. QJM. 2010;103:1000–2.

    Article  CAS  PubMed  Google Scholar 

  13. Nieweg OE, Pruim J, van Ginkel RJ, Hoekstra HJ, Paans AM, Molenaar WM, et al. Fluorine-18-fluorodeoxyglucose PET imaging of soft-tissue sarcoma. J Nucl Med. 1996;37:257–61.

    CAS  PubMed  Google Scholar 

  14. Shin DS, Shon OJ, Han DS, Choi JH, Chun KA, Cho IH. The clinical efficacy of (18)F-FDG-PET/CT in benign and malignant musculoskeletal tumors. Ann Nucl Med. 2008;22:603–9.

    Article  PubMed  Google Scholar 

  15. Nakatani K, Nakamoto Y, Togashi K. Unilateral physiological FDG uptake in teres minor muscle seems well associated with IV tracer injection procedures. Clin Nucl Med. 2015;40:62–4.

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Radiology, Tokushima University Hospital, Tokushima, 2-50-1 Kuramoto-cho, Tokushima, 770-8503, Japan

    Yoichi Otomi, Takayoshi Shinya, Naoto Uyama, Kanako Miyamoto, Michiko Kubo & Masafumi Harada

  2. Department of Radiology, Tokushima Red Cross Hospital, Tokushima, Japan

    Yuta Arai & Katsuya Takechi

  3. Department of Medical Imaging/Nuclear Medicine, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan

    Hideki Otsuka

Authors
  1. Yoichi Otomi
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  2. Takayoshi Shinya
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  3. Naoto Uyama
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  4. Yuta Arai
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  5. Kanako Miyamoto
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  6. Katsuya Takechi
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  7. Michiko Kubo
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  8. Hideki Otsuka
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  9. Masafumi Harada
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Corresponding author

Correspondence to Yoichi Otomi.

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Conflict of interest

The authors have no conflict of interest to disclose with respect to this work.

Ethical statement

This study was approved without the need for individual informed consent by our institutional ethics committee and is in accordance with the 1964 Declaration of Helsinki and its later amendments.

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Cite this article

Otomi, Y., Shinya, T., Uyama, N. et al. The physiological accumulation of FDG in the muscles in relation to the side of intravenous administration. Jpn J Radiol 35, 53–60 (2017). https://doi.org/10.1007/s11604-016-0597-4

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  • DOI: https://doi.org/10.1007/s11604-016-0597-4

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