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Proton magnetic resonance spectroscopy findings of hemangioblastoma

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Abstract

We report a case of proton magnetic resonance spectroscopy (MRS) of hemangioblastoma in a 56-yearold man with a history of hyperlipidemia who was suffering from an equilibrium disorder. Proton MRS revealed a high mobile lipids (Lip) peak between 0.9 and 1.4 ppm, which was compatible with histologically proven lipids in the tumor. No lactate peak was recognized. The creatine/phosphocreatine peak was low. Choline-containing compounds were increased. The N-acetylaspartate peak was absent, which indicated that the tumor is of nonneurogenic origin. Combined with the absence of the necrotic component on magnetic resonance imaging, this Lip peak on proton MRS could be the characteristic pattern of hemangioblastoma. These unique results of proton MRS can play an important role in the differential diagnosis of intracranial hemangioblastoma. However, further investigations are required to establish the typical characteristics of proton MRS of hemangioblastoma.

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Authors and Affiliations

  1. Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Japan

    Tomonori Isobe

  2. Department of Neurosurgery, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8575, Japan

    Tetsuya Yamamoto, Hiroyoshi Akutsu, Alexander Zaboronok, Shingo Takano & Akira Matsumura

  3. Department of Radiological Sciences, Ibaraki Prefectural University of Health Sciences, Ibaraki, Japan

    Izumi Anno

  4. Department of Radiology, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Japan

    Masanari Shiigai & Tomohiko Masumoto

Authors
  1. Tomonori Isobe
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  2. Tetsuya Yamamoto
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  3. Hiroyoshi Akutsu
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  4. Izumi Anno
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  5. Masanari Shiigai
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  6. Alexander Zaboronok
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  7. Tomohiko Masumoto
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  8. Shingo Takano
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  9. Akira Matsumura
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Corresponding author

Correspondence to Tetsuya Yamamoto.

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Isobe, T., Yamamoto, T., Akutsu, H. et al. Proton magnetic resonance spectroscopy findings of hemangioblastoma. Jpn J Radiol 28, 318–321 (2010). https://doi.org/10.1007/s11604-010-0421-5

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  • DOI: https://doi.org/10.1007/s11604-010-0421-5

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