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Diagnostic performance of fluorodeoxyglucose positron emission tomography/magnetic resonance imaging fusion images of gynecological malignant tumors: comparison with positron emission tomography/computed tomography

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Abstract

Purpose

We compared the diagnostic accuracy of fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) and PET/magnetic resonance imaging (MRI) fusion images for gynecological malignancies.

Materials and methods

A total of 31 patients with gynecological malignancies were enrolled. FDG-PET images were fused to CT, T1- and T2-weighted images (T1WI, T2WI). PET-MRI fusion was performed semiautomatically. We performed three types of evaluation to demonstrate the usefulness of PET/MRI fusion images in comparison with that of inline PET/CT as follows: depiction of the uterus and the ovarian lesions on CT or MRI mapping images (first evaluation); additional information for lesion localization with PET and mapping images (second evaluation); and the image quality of fusion on interpretation (third evaluation).

Results

For the first evaluation, the score for T2WI (4.68 ± 0.65) was significantly higher than that for CT (3.54 ± 1.02) or T1WI (3.71 ± 0.97) (P < 0.01). For the second evaluation, the scores for the localization of FDG accumulation showing that T2WI (2.74 ± 0.57) provided significantly more additional information for the identification of anatomical sites of FDG accumulation than did CT (2.06 ± 0.68) or T1WI (2.23 ± 0.61) (P < 0.01). For the third evaluation, the three-point rating scale for the patient group as a whole demonstrated that PET/T2WI (2.72 ± 0.54) localized the lesion significantly more convincingly than PET/CT (2.23 ± 0.50) or PET/T1WI (2.29 ± 0.53) (P < 0.01).

Conclusion

PET/T2WI fusion images are superior for the detection and localization of gynecological malignancies.

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Authors and Affiliations

  1. Department of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, 565-0871, Japan

    Kazuya Nakajo, Mitsuaki Tatsumi, Atsuo Inoue, Kayako Isohashi, Ichiro Higuchi, Hiroki Kato, Masao Imaizumi, Eku Shimosegawa & Jun Hatazawa

  2. Department of Radiology, Osaka University Hospital, Suita, Japan

    Jun Hatazawa

  3. Department of Obstetrics and Gynaecology, Osaka University Graduate School of Medicine, Suita, Japan

    Takayuki Enomoto & Tadashi Kimura

Authors
  1. Kazuya Nakajo
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  2. Mitsuaki Tatsumi
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  3. Atsuo Inoue
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  4. Kayako Isohashi
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  5. Ichiro Higuchi
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  6. Hiroki Kato
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  7. Masao Imaizumi
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  8. Takayuki Enomoto
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  9. Eku Shimosegawa
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  10. Tadashi Kimura
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  11. Jun Hatazawa
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Corresponding author

Correspondence to Jun Hatazawa.

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Nakajo, K., Tatsumi, M., Inoue, A. et al. Diagnostic performance of fluorodeoxyglucose positron emission tomography/magnetic resonance imaging fusion images of gynecological malignant tumors: comparison with positron emission tomography/computed tomography. Jpn J Radiol 28, 95–100 (2010). https://doi.org/10.1007/s11604-009-0387-3

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  • DOI: https://doi.org/10.1007/s11604-009-0387-3

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