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Preparation of filling porous osteoconduction materials and its animal experiment study

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Abstract

Titanium rods were processed into implant samples with cavity and groove in which was filled with HAP/β-TCP porous osteoconduction composite materials in order to increase the mechanical stability of the implant in vivo. The phase compositions of the composite was characterized by X-ray diffraction (XRD) and scanning electron microscopy(SEM). Histological evaluation showed that the biogradable composite could enhanced the ability of new bone formation. The composite can conduct new bone tissue growing into the cavities gradually after implanted into animal, and then achieve mechanical fixation. The filling biogradable compound exhibited excellent biocompatibility, which combined with the new bone tissues tightly without inflammation and loosing.

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Authors and Affiliations

  1. Biomedical Materials and Engineering Research Center, Wuhan University of Technology, Wuhan, 430070, China

    Xiaoming Chen  (陈晓明) & Jing Wang

  2. Animal Experiment Center, Zhongnan Hospital of Wuhan University, Wuhan, 430077, China

    Weimin Chen

  3. Devision of Electron Microscope, Guangzhou Military Area Wuhan General Hospital, Wuhan, 430070, China

    Dezhong Li

Authors
  1. Xiaoming Chen  (陈晓明)
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  2. Jing Wang
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  3. Weimin Chen
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  4. Dezhong Li
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Corresponding author

Correspondence to Xiaoming Chen  (陈晓明).

Additional information

Funded by the National Natural Science Foundation of China (No. 50872099)

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Chen, X., Wang, J., Chen, W. et al. Preparation of filling porous osteoconduction materials and its animal experiment study. J. Wuhan Univ. Technol.-Mat. Sci. Edit. 26, 231–234 (2011). https://doi.org/10.1007/s11595-011-0203-7

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  • DOI: https://doi.org/10.1007/s11595-011-0203-7

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