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Melt synthesis and characterization of poly(L-lactic acid) chain linked by multifunctional epoxy compound

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Abstract

High molecular weight(Mw) poly(L-lactic acid)s(PLLAs) were synthesized using multifunctional epoxy compound(Joncryl-ADR4370) as chain extender. The products were characterized by gel permeation chromatography(GPC) and spectroscopy(1HNMR and FTIR). The results indicated that the Mw of PLLA increased with the increasing of the ratio of epoxy compound and the extending of reaction time. The highest M w of PLLA reached 360 000 g/mol when the ratio of epoxy compound was 1.5 wt%. However, the reactants turned to cross-linking when the ratio of epoxy compound was over 1.5 wt%. Differential scanning calorimetry(DSC) measurements demonstrated that the glass transition(T g) and melting temperatures(T m ) of products increased slightly as the increase of the molecular weight. Analysis of the hydrolytic degradation in vitro showed that the branched PLLA possessed the quicker degradability than that of the linear PLLA.

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Authors and Affiliations

  1. Research Center of Bioinspired Materials Science and Engineering, Bioengineering College, Chongqing University, Chongqing, 400044, China

    Yuanliang Wang  (王远亮), Chunhua Fu, Yongxiang Luo, Changshun Ruan, Yaoyao Zhang & Ya Fu

  2. Department of Biology, Chongqing University of Science and Technology, Chongqing, 401331, China

    Ya Fu

Authors
  1. Yuanliang Wang  (王远亮)
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  2. Chunhua Fu
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  3. Yongxiang Luo
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  4. Changshun Ruan
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  5. Yaoyao Zhang
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  6. Ya Fu
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Corresponding author

Correspondence to Yuanliang Wang  (王远亮).

Additional information

Funded by the National Natural Science Foundation of China (No. 30870609), the Natural Science Foundation of Chongqing (Nos.2009BA4025 and CSTC2009BB4382) and the Foundation of Chongqing Municipal Education Commission(No.KJ091415)

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Wang, Y., Fu, C., Luo, Y. et al. Melt synthesis and characterization of poly(L-lactic acid) chain linked by multifunctional epoxy compound. J. Wuhan Univ. Technol.-Mat. Sci. Edit. 25, 774–779 (2010). https://doi.org/10.1007/s11595-010-0090-3

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  • DOI: https://doi.org/10.1007/s11595-010-0090-3

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