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New voltammetric strategy for simultaneous determination of norepinephrine, acetaminophen, and folic acid using a 5-amino-3′,4′-dimethoxy-biphenyl-2-ol/carbon nanotube paste electrode

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Abstract

A carbon paste electrode modified with 5-amino-3′,4′-dimethoxy-biphenyl-2-ol and carbon nanotubes was used for the sensitive voltammetric determination of norepinephrine (NE). The electrochemical response characteristics of the modified electrode toward NE, acetaminophen (AC), and folic acid (FA) were investigated by cyclic and square wave voltammetry (SWV). The results show an efficient catalytic activity of the electrode for the electrooxidation of NE, which leads to lowering its overpotential more than 160 mV. The modified electrode exhibits an efficient electron-mediating behavior together with well-separated oxidation peaks for NE, AC, and FA. Under the optimum pH of 7.0 in 0.1 M phosphate buffer solution, the SWV anodic peak current showed a linear relation vs. NE concentration in the range of 15.0 to 1,000.0 μM with a detection limit of 8.0 μM.

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Authors and Affiliations

  1. Environment Department, Research Institute of Environmental Sciences, International Center for Science, High Technology & Environmental Sciences, Kerman, Iran

    Hadi Beitollahi

  2. Department of Chemistry, Payame Noor University, PO Box 19395-3697, Tehran, Iran

    Alireza Mohadesi, Saeedeh Khalilizadeh Mahani & Ali Akbari

  3. Department of Chemistry, Majlesi Branch, Islamic Azad University, Isfahan, Iran

    Hassan Karimi-Maleh

Authors
  1. Hadi Beitollahi
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  2. Alireza Mohadesi
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  3. Saeedeh Khalilizadeh Mahani
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  4. Hassan Karimi-Maleh
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  5. Ali Akbari
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Correspondence to Hadi Beitollahi.

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Beitollahi, H., Mohadesi, A., Khalilizadeh Mahani, S. et al. New voltammetric strategy for simultaneous determination of norepinephrine, acetaminophen, and folic acid using a 5-amino-3′,4′-dimethoxy-biphenyl-2-ol/carbon nanotube paste electrode. Ionics 18, 703–710 (2012). https://doi.org/10.1007/s11581-012-0669-0

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  • DOI: https://doi.org/10.1007/s11581-012-0669-0

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