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A functional approach toward xerogel immobilization for encapsulation biocompatibility of Rhizobium toward biosensor

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Frontiers in Biology

Abstract

Sol-gel derived silica has tremendous applications as a biocompatible scaffold for the immobilization of cells. The use of xerogel as a matrix in the blueprint of biosensors is an appealing proposition due to several inimitable characteristics of xerogels, primarily because of their high porous nature, amendable pore size, and exceptionally large internal surface area. Morphological (X-Ray Diffraction and Thermogravimmetric Analysis) and optical (Fourier Transform Infrared and UV-Vis absorption) studies of the silica matrices with entrapped Rhizobial (Rz) structure of the biomaterial has been made. Temporal and concentration dependent studies were conducted for impregnated samples; it showed that the response time for the new biosensor for determining the concentration of Rz is less than 20 min. In this work, first time a novel avenue to create a generic approach for the fabrication of biosensor has been created.

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Author notes

  1. Sunita Sharma

    Present address: Nanostech Lab, Department of Physics, Indian Institute of Technology, Delhi, India

Authors and Affiliations

  1. Department of Bio and Nano Technology, Guru Jambheshwar University of Science and Technology, Hisar, 125001, Haryana, India

    Pooja Arora, Neeraj Dilbaghi & Ashok Chaudhury

  2. Light and Matter Physics Group, Raman Research Institute, Bangalore, India

    Sunita Sharma

  3. Physics Department, University Teknologi of Malaysia, Malaysia, Malaysia

    Sib Krishna Ghoshal

Authors
  1. Pooja Arora
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  2. Sunita Sharma
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  3. Sib Krishna Ghoshal
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  4. Neeraj Dilbaghi
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  5. Ashok Chaudhury
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Corresponding authors

Correspondence to Sunita Sharma, Neeraj Dilbaghi or Ashok Chaudhury.

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Arora, P., Sharma, S., Ghoshal, S.K. et al. A functional approach toward xerogel immobilization for encapsulation biocompatibility of Rhizobium toward biosensor. Front. Biol. 8, 626–631 (2013). https://doi.org/10.1007/s11515-013-1286-7

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  • DOI: https://doi.org/10.1007/s11515-013-1286-7

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