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Electrospun PEO/WPI Nanofibers with Vanillin for Food Applications

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Abstract

In this study, we successfully fabricated vanillin (VAN) incorporated poly (ethylene oxide) (PEO) and whey protein isolate (WPI) nanofibers and optimized the preparation conditions. The nanofibers were prepared at different percentages of PEO/WPI/VAN, and the characterization techniques of XRD, FTIR, FESEM, and DSC were employed to analyze the samples. Additionally, mechanical properties, and physicochemical were measured to identify the critical factors for nanofiber optimization. The best parameters observed at a PEO 10%: WPI 3% ratio of 80:20, producing narrower and smoother fibers (average diameter of 264.07 nm; additionally, the addition of VAN to the optimal PEO/WPI ratio (80:20) decreased fiber diameter. Furthermore, vanillin was incorporated into the optimized PEO/WPI nanofibers at concentrations of 1MIC (10 mg/mL) and 2MIC (20 mg/mL) to evaluate their antioxidant and antibacterial abilities before and after electrospinning. In summery, these findings suggest that the PEO/WPI nanofibers, with the addition of VAN, hold potential as a promising platform for future applications in the food and drug industries. Further research can build upon these findings to explore the specific functionalities and applications of these nanofibers in greater detail.

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References

  1. B. Wang, S. Wang, Q. Zhang, Y. Deng, X. Li, L. Peng, X. Zuo, M. Piao, X. Kuang, S. Sheng, Acta Biomater. 96, 55 (2019)

    Article  CAS  PubMed  Google Scholar 

  2. S. Kang, S. Hou, X. Chen, D.-G. Yu, L. Wang, X. Li, G.R. Williams, Polym. (Basel). 12, 2421 (2020)

    Article  CAS  Google Scholar 

  3. X. Huang, W. Jiang, J. Zhou, D.-G. Yu, H. Liu, Polym. (Basel). 14, 4947 (2022)

    Article  CAS  Google Scholar 

  4. M. Wang, J. Hou, D.-G. Yu, S. Li, J. Zhu, Z. Chen, J. Alloys Compd. 846, 156471 (2020)

    Article  CAS  Google Scholar 

  5. Y. Wang, D.-G. Yu, Y. Liu, Y.-N. Liu, J. Funct. Biomater. 13, 289 (2022)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. J. Zhou, T. Yi, Z. Zhang, D.-G. Yu, P. Liu, L. Wang, Y. Zhu, Adv. Compos. Hybrid. Mater. 6, 189 (2023)

    Article  CAS  Google Scholar 

  7. Y. Wang, L. Liu, Y. Zhu, L. Wang, D.-G. Yu, L. Liu, Pharmaceutics. 15, 2561 (2023)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. D.-G. Yu, C. Huang, Biomolecules. 13, 1152 (2023)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. J. Li, Q. Du, J. Wan, D.-G. Yu, F. Tan, X. Yang, Mater. Des. 238, 112657 (2024)

    Article  CAS  Google Scholar 

  10. D.-G. Yu, J. Zhou, J. Pharm. Sci. 112, 2719 (2023)

    Article  CAS  PubMed  Google Scholar 

  11. K. Chen, Y. Li, Y. Li, Y. Tan, Y. Liu, W. Pan, G. Tan, J. Nanobiotechnol. 21, 237 (2023)

    Article  CAS  Google Scholar 

  12. R. Ge, Y. Ji, Y. Ding, C. Huang, H. He, D.-G. Yu, Front. Bioeng. Biotechnol. 11, 1112338 (2023)

    Article  PubMed  PubMed Central  Google Scholar 

  13. Y. Du, D.-G. Yu, T. Yi, Chemosensors. 11, 208 (2023)

    Article  CAS  Google Scholar 

  14. M.K. Gaydhane, C.S. Sharma, S. Majumdar, RSC Adv. 13, 7312 (2023)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  15. R. Contreras-Cáceres, L. Cabeza, G. Perazzoli, A. Díaz, J.M. López-Romero, C. Melguizo, J. Prados, Nanomaterials. 9, 656 (2019)

    Article  PubMed  PubMed Central  Google Scholar 

  16. S. Amjadi, H. Almasi, H. Hamishehkar, M.A. Khaledabad, L.-T. Lim, S. Gholizadeh, Food Biophys. 1 (2023)

  17. K. Mahmood, H. Kamilah, A.A. Karim, F. Ariffin, Food Biophys. 18, 186 (2023)

    Article  Google Scholar 

  18. F.N. dos Santos, E.J.D. de Souza, J.F. de Souza, J.B. Pires, T.J. Siebeneichler, D.H. Kringel, A.R. Fajardo, C.V. Rombaldi, A.R.G. Dias, and E. da Rosa Zavareze, Food Biophys. 18, 133 (2023)

  19. Y. Wu, H. Wu, L. Hu, Food Biophys. 19, 29 (2024)

    Article  Google Scholar 

  20. T. Chen, H. Liu, C. Deng, D. Zhang, H. Li, C. Zhou, P. Hong, Food Biophys. 18, 580 (2023)

    Article  Google Scholar 

  21. L. Zhao, G. Duan, G. Zhang, H. Yang, S. He, S. Jiang, Nanomaterials. 10, 150 (2020)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  22. J.H. Lee, J. Kopecek, J.D. Andrade, J. Biomed. Mater. Res. 23, 351 (1989)

    Article  PubMed  Google Scholar 

  23. N.P. Desai, J.A. Hubbell, Biomaterials. 12, 144 (1991)

    Article  CAS  PubMed  Google Scholar 

  24. B.A. Miller-Chou, J.L. Koenig, Prog Polym. Sci. 28, 1223 (2003)

    Article  CAS  Google Scholar 

  25. P. Dubey, P. Gopinath, J. Mater. Chem. B 4, 726 (2016)

    Article  CAS  PubMed  Google Scholar 

  26. C. Drosou, M. Krokida, C.G. Biliaderis, Food Hydrocoll. 77, 726 (2018)

    Article  CAS  Google Scholar 

  27. M. Mohammadi, S. Mirabzadeh, R. Shahvalizadeh, H. Hamishehkar, Int. J. Biol. Macromol. 149, 11 (2020)

    Article  CAS  PubMed  Google Scholar 

  28. F. Samadani, T. Behzad, M.S. Enayati, Int. J. Biol. Macromol. 139, 858 (2019)

    Article  CAS  PubMed  Google Scholar 

  29. G. Aslaner, G. Sumnu, S. Sahin, Food Bioprocess. Technol. 14, 1118 (2021)

    Article  CAS  Google Scholar 

  30. Ö. Zambak, A. Özkal, S.G. Özkal, J. Appl. Polym. Sci. 139, e53141 (2022)

    Article  CAS  Google Scholar 

  31. N.B. Tatlisu, M.T. Yilmaz, M. Arici, Food Packag Shelf Life. 21, 100347 (2019)

    Article  Google Scholar 

  32. M. Shariatikia, M. Behbahani, H. Mohabatkar, Mol. Biol. Res. Commun. 6, 57 (2017)

    CAS  PubMed  PubMed Central  Google Scholar 

  33. D. Brumini, A. Criscione, S. Bordonaro, G.E. Vegarud, D. Marletta, Dairy. Sci. Technol. 96, 1 (2016)

    Article  CAS  Google Scholar 

  34. M. Salami, A.A. Moosavi-Movahedi, M.R. Ehsani, R. Yousefi, T. Haertle, J.-M. Chobert, S.H. Razavi, R. Henrich, S. Balalaie, S.A. Ebadi, J. Agric. Food Chem. 58, 3297 (2010)

    Article  CAS  PubMed  Google Scholar 

  35. T.B. Ng, R.C.F. Cheung, J.H. Wong, Y. Wang, D.T.M. Ip, D.C.C. Wan, J. Xia, Appl. Microbiol. Biotechnol. 99, 6997 (2015)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  36. V. Gallo, F. Giansanti, A. Arienzo, G. Antonini, J. Funct. Foods 104932 (2022)

  37. L. Kang, Y. Gao, X. Liu, Y. Liang, Y. Chen, Y. Liang, L. Zhang, W. Chen, H. Pang, L.-N. Peng, Arch. Gerontol. Geriatr. 83, 7 (2019)

    Article  CAS  PubMed  Google Scholar 

  38. M. Mitchell, N.P. Brutnon, R.J. Fitzgerald, M.G. Wilkinson, J. Culin. Sci. Technol. 11, 222 (2013)

    Article  Google Scholar 

  39. A. García, L.M. Perez, G.N. Piccirilli, R.A. Verdini, LWT. 117, 108587 (2020)

    Article  Google Scholar 

  40. A.S. Eissa, S.A. Khan, J. Agric. Food Chem. 53, 5010 (2005)

    Article  CAS  PubMed  Google Scholar 

  41. C. Zhang, Y. Li, P. Wang, H. Zhang, Compr. Rev. Food Sci. Food Saf. 19, 479 (2020)

    Article  CAS  PubMed  Google Scholar 

  42. D.L. Woerdeman, S. Shenoy, D. Breger, J. Adhes. 83, 785 (2007)

    Article  CAS  Google Scholar 

  43. L. Fu, K. Xie, D. Wu, A. Wang, H. Zhang, Z. Ji, Mater. Chem. Phys. 242, 122462 (2020)

    Article  CAS  Google Scholar 

  44. A. Venkadesh, J. Mathiyarasu, S. Radhakrishnan, Mater. Today Chem. 22, 100554 (2021)

    Article  CAS  Google Scholar 

  45. T.R. Silva, D. Brondani, E. Zapp, I Cruz Vieira Electroanalysis. 27, 465 (2015)

    Article  CAS  Google Scholar 

  46. S. Durant, P. Karran, Nucleic Acids Res. 31, 5501 (2003)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  47. T. Zabihpour, S.-A. Shahidi, H. Karimi-Maleh, A. Ghorbani-HasanSaraei, J. Food Meas. Charact. 14, 1039 (2020)

    Article  Google Scholar 

  48. P. Deng, Z. Xu, R. Zeng, C. Ding, Food Chem. 180, 156 (2015)

    Article  CAS  PubMed  Google Scholar 

  49. C. Anandharamakrishnan, Techniques for Nanoencapsulation of Food Ingredients (Springer, 2014)

  50. M. Maleki, M. Mohsenzadeh, J. Food Process. Preserv. 46, e16424 (2022)

    Article  CAS  Google Scholar 

  51. C. J. F. Dias, A. Raposo, C. D. T. de Sousa, J. B. de Araújo-Neto, S. R. Tintino, C. D. de M. Oliveira-Tintino, I. M. Araújo, H. D. M. Coutinho, M. G. M. Costa, C. G. Lima, Biology (Basel). 11, 1835 (2022)

  52. Z. Panahi, M. Mohsenzadeh, M. Hashemi, Nanomed. J. (2023)

  53. N. Doğan, C. Doğan, A.K. Eticha, M. Gungor, Y. Akgul, Food Control. 139, 109081 (2022)

    Article  Google Scholar 

  54. F. E.-Z Amrati, M. Bourhia, M. Slighoua, S. Ibnemoussa, A. Bari, R. Ullah, A. Amaghnouje, F. Di Cristo, M. El. Mzibri, A. Calarco, L. Benbacer, D. Bousta, Evid. Based Complement. Alternat. Med. (2020)

  55. A. Vega-Lugo, L. Lim, J. Polym. Sci. Part. B Polym. Phys. 50, 1188 (2012)

  56. M. Keramat, S. Esteghlal, J. Safari, M.-T. Golmakani, M. Khalesi, Nanosci. Nanotechnology-Asia. 9, 371 (2019)

    Article  CAS  Google Scholar 

  57. G.R. Williams, B.T. Raimi-Abraham, C.J. Luo, Nanofibres in Drug Delivery (UCL, 2018)

  58. N. Bhardwaj, S.C. Kundu, Biotechnol. Adv. 28, 325 (2010)

    Article  CAS  PubMed  Google Scholar 

  59. P. Gupta, C. Elkins, T.E. Long, G.L. Wilkes, Polym. (Guildf). 46, 4799 (2005)

    Article  CAS  Google Scholar 

  60. F. Kayaci, T. Uyar, Food Chem. 133, 641 (2012)

    Article  CAS  Google Scholar 

  61. A. Rezaei, A. Nasirpour, H. Tavanai, M. Fathi, Flavour. Fragr. J. 31, 442 (2016)

    Article  CAS  Google Scholar 

  62. A. Abedi, M. Hasanzadeh, L. Tayebi, Mater. Chem. Phys. 237, 121882 (2019)

    Article  CAS  Google Scholar 

  63. T.D.J. Heunis, C. Smith, L.M.T. Dicks, Antimicrob. Agents Chemother. 57, 3928 (2013)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  64. J. Colin-Orozco, M. Zapata-Torres, G. Rodriguez-Gattorno, R. Pedroza-Islas, Food Biophys. 10, 134 (2015)

    Article  Google Scholar 

  65. O.V. Surov, M.I. Voronova, A.V. Afineevskii, A.G. Zakharov, Carbohydr. Polym. 181, 489 (2018)

    Article  CAS  PubMed  Google Scholar 

  66. P. Wang, H. Wang, J. Liu, P. Wang, S. Jiang, X. Li, S. Jiang, Carbohydr. Polym. 181, 885 (2018)

    Article  CAS  PubMed  Google Scholar 

  67. A. Zaitoon, L.-T. Lim, Materialia. 10, 100649 (2020)

    Article  CAS  Google Scholar 

  68. Z.-H. Zhang, Z. Han, X.-A. Zeng, X.-Y. Xiong, Y.-J. Liu, Int. J. Biol. Macromol. 81, 638 (2015)

    Article  CAS  PubMed  Google Scholar 

  69. X. Xu, L. Jiang, Z. Zhou, X. Wu, Y. Wang, ACS Appl. Mater. Interfaces. 4, 4331 (2012)

    Article  CAS  PubMed  Google Scholar 

  70. H.-J. Lee, C.D.G. Abueva, A.R. Padalhin, B.-T. Lee, J. Biomater. Appl. 34, 1142 (2020)

    Article  CAS  PubMed  Google Scholar 

  71. D.E. Hegazy, G.A. Mahmoud, Arab. J. Nucl. Sci. Appl. 47, 1 (2014)

    Google Scholar 

  72. L. Yong, L. Jia, F. Jie, W. Meng, Matéria (Rio Janeiro). 19, 382 (2014)

    Article  Google Scholar 

  73. R.A.C. Gomide, A.C.S. de Oliveira, L.B. Luvizaro, M.I. Yoshida, C.R. de Oliveira, S.V. Borges, J. Food Process. Eng. 44, e13596 (2021)

    Article  CAS  Google Scholar 

  74. G.K. Gbassi, F.S. Yolou, S.O. Sarr, P.G. Atheba, C.N. Amin, M. Ake, Int. J. Biol. Chem. Sci. 6, 1828 (2012)

    Google Scholar 

  75. A. Asdagh, I. Karimi Sani, S. Pirsa, S. Amiri, N. Shariatifar, H. Eghbaljoo–Gharehgheshlaghi, Z. Shabahang, A. Taniyan, J. Polym. Environ. 29, 335 (2021)

    Article  CAS  Google Scholar 

  76. S. Solghi, Z. Emam-Djomeh, M. Fathi, F. Farahani, J. Food Process. Eng. 43, e13403 (2020)

    Article  CAS  Google Scholar 

  77. A. Dey, S. Karan, S.K. De, Solid State Commun. 149, 1282 (2009)

    Article  CAS  Google Scholar 

  78. R.V. de Fernandes, S.V. Borges, D.A. Botrel, C.R. de Oliveira, Int. J. Food Sci. Technol. 49, 1522 (2014)

    Article  CAS  Google Scholar 

  79. S. Nasr, J. Varshosaz, V. Hajhashemi, Pharmacol. Rep. 72, 680 (2020)

    Article  CAS  PubMed  Google Scholar 

  80. R. Chollakup, S. Pongburoos, W. Boonsong, N. Khanoonkon, K. Kongsin, R. Sothornvit, P. Sukyai, U. Sukatta, N. Harnkarnsujarit, Lwt. 130, 109573 (2020)

    Article  CAS  Google Scholar 

  81. M. Grkovic, D.B. Stojanovic, V.B. Pavlovic, M. Rajilic-Stojanovic, M. Bjelovic, P.S. Uskokovic, Compos. Part. B Eng. 121, 58 (2017)

    Article  CAS  Google Scholar 

  82. I. Mourtzinos, S. Konteles, N. Kalogeropoulos, V.T. Karathanos, Food Chem. 114, 791 (2009)

  83. A. Aarabi, H. Ebadi-Dehaghani, and S. Saiedi, Food Hyg. 5, 1 (2015).

  84. D.J. Fitzgerald, M. Stratford, A. Narbad, Int. J. Food Microbiol. 86, 113 (2003)

    Article  CAS  PubMed  Google Scholar 

  85. O.P. Sharma, T.K. Bhat, Food Chem. 113, 1202 (2009)

    Article  CAS  Google Scholar 

  86. W. Liu, X.D. Chen, Z. Cheng, C. Selomulya, J. Food Eng. 169, 189 (2016)

    Article  CAS  Google Scholar 

  87. Z.-H. Zhang, H. Peng, M.W. Woo, X.-A. Zeng, M. Brennan, C.S. Brennan, J. Food Eng. 267, 109729 (2020)

    Article  CAS  Google Scholar 

  88. A. Tai, T. Sawano, F. Yazama, H. Ito, Biochim. Biophys. Acta (BBA)-General Subj. 1810, 170 (2011)

  89. A. Celebioglu, F. Kayaci-Senirmak, S. İpek, E. Durgun, T. Uyar, Food Funct. 7, 3141 (2016)

    Article  CAS  PubMed  Google Scholar 

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Acknowledgements

The authors would like to thanks Mrs Samira Khajenasiri for technical helps.

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B.J.: Data curation, Methodology, Visualization, Writing - original draft preparation, Investigation. M.M.: Conceptualization, Investigation, Methodology, Writing - original draft preparation, Writing - Review & Editing, Visualization , Supervision, Project administration, Funding acquisition.

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Correspondence to Mohammad Mohsenzadeh.

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Javadi, B., Mohsenzadeh, M. Electrospun PEO/WPI Nanofibers with Vanillin for Food Applications. Food Biophysics (2024). https://doi.org/10.1007/s11483-024-09832-y

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