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High-Performance Plasmonic Sensor Based on Silver, Gold and Graphene Layers for Cancer Cell Detection at 632.8 nm Wavelength with Photonic Spin Hall Effect

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Abstract

In this work, a transverse spin-dependent shift of the horizontal photonic spin Hall effect at a fixed wavelength (0.6328 μm) is simulated for cancer cell detection based on refractive index, chemical potential, and electrical voltage variations applied to a plasmonic sensor with five layers (Ge20Ga5Sb10S65 chalcogenide prism, silver, gold, grapheme, and cancerous medium). When the conventional weak measurement is applied and when the chemical potential is increased from 0.3 eV to 8 eV, the chemical and voltage resolutions are 3.87 × 10–7 eV, 13.3327 μV for n5 = 1.38 RIU (cancerous skin cell), 5.17 × 10–7 eV, 17.7889 μV for n5 = 1.392 RIU (cancerous cervical cell), 4.95 × 10–7 eV, 17.0249 μV for n5 = 1.390 RIU (cancerous blood cell), and 5.50 × 10–7 eV, 18.9514 μV for n5 = 1.395 RIU (cancerous adrenal gland cell), respectively. The values of the chemical and voltage resolutions (1.90 × 10–7 eV, 6.5560 μV for n5 = 1.36 RIU and normal skin cell) are better than for the case when the spin Hall effect is not applied (0.00513 eV, 0.1766 V). The voltage resolutions calculated with the conventional weak measurement method are comparable or considerably better to the best experimental values which can resolve voltage differences as small as 15 μV.

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References

  1. Mostufa S, Akib TBA, Rana MdM, Islam MdR (2022) Highly sensitive TiO2/Au/Graphene layer-based surface plasmon resonance biosensor for cancer detection. Biosensors 12(603):1–22. https://doi.org/10.3390/bios12080603

    Article  CAS  Google Scholar 

  2. Gollapalli R, Phillips J, Paul P (2023) Ultrasensitive surface plasmon resonance sensor with a feature of dynamically tunable sensitivity and high figure of merit for cancer detection. Sensors 23(5590):1–21. https://doi.org/10.3390/s23125590

    Article  CAS  Google Scholar 

  3. Singh S, Sharma AK, Lohia P, Dwivedi DK, Kumar V, Singh PK (2023) Simulation study of reconfigurable surface plasmon resonance refractive index sensor employing bismuth telluride and MXene nanomaterial for cancer cell detection. Phys Scr 98:025813. https://doi.org/10.1088/1402-4896/acb023

  4. Karki B, Unival A, Pal A, Srivastava V (2022) Advances in surface plasmon resonance-based biosensor technologies for cancer cell detection. Int J Opt 1476254:1–10. https://doi.org/10.1155/2022/1476254

    Article  CAS  Google Scholar 

  5. Popescu VA, Sharma AK (2023) Microstructured and non-microstructured fiber-based plasmonic sensors for high-performance and wide-range detection of different parameters. In: Gupta BD, Sharma AK, Li J (ed) Plasmonics-based optical sensors and detectors, Jenny Stanford Publishing. ISBN 9781003438304

  6. Karki B, Salah NH, Srivastava G, Muduli A, Yadav RB (2023) A simulation study for dengue virus detection using surface plasmon resonance sensor heterostructure of silver, barium titanate and cerium oxide. Plasmonics Published online: 29 June 2023. https://doi.org/10.1007/s11468-023-01907-9

  7. Wang Q, Cao S, Gao X, Chen X, Zhang D (2022) Improving the detection accuracy of an Ag/Au bimetallic surface plasmon resonance biosensor based on graphene. Chemosensors 10(10):1–13. https://doi.org/10.3390/bios12080603

    Article  CAS  Google Scholar 

  8. Gollapalli RP (2020) Enhanced sensitivity in graphene-based SPR biosensors using electrical bias. Opt Lett 45(10):2862–2865. https://doi.org/10.1364/OL.391504h

    Article  ADS  PubMed  Google Scholar 

  9. Sharma AK, Nagao T (2014) Design of a silicon-based plasmonic optical sensor for magnetic field monitoring in the infrared. App Phys B 117:363–368. https://doi.org/10.1007/s00340-014-5843-9

    Article  ADS  CAS  Google Scholar 

  10. Zhou X, Sheng L, Ling X (2018) Photonic spin Hall effect enabled RI sensor using weak measurements. Sci Rep 8:1221. https://doi.org/10.1038/s41598-018-19713-3

    Article  ADS  CAS  PubMed  PubMed Central  Google Scholar 

  11. Hong CY, Horng HE, Yang SY (2004) Tunable refractive index of magnetic fluids and its applications. Phys Stat Sol (c) 1:1604. https://doi.org/10.1002/pssc.200304388

    Article  CAS  Google Scholar 

  12. Popescu VA, Prajapati YK, Sharma AK (2021) Highly sensitive magnetic field detection in infrared region with photonic spin Hall effect in silicon waveguide plasmonic sensor. IEEE Trans Magn 57(4002210):1–10. https://doi.org/10.1109/TMAG.2021.3103651

    Article  Google Scholar 

  13. Popescu VA, Sharma AK, Prajapati YK (2022) Graphene-based spin Hall effect in a broad plasmonic detection of magnetic field and gaseous medium with photonic terahertz region. J Electron Mater 51:2889–2899. https://doi.org/10.1007/s11664-022-09537-3

    Article  ADS  CAS  Google Scholar 

  14. Popescu VA, Chauhan K, Prajapati YK, Sharma AK (2023) Design and analysis of graphene-and germanium-based plasmonic probe with photonic spin Hall effect in THz frequency region for magnetic field and refractive index sensing. Opt Quant Electron 55(135):1–16. https://doi.org/10.1007/s11082-022-04384-2

    Article  CAS  Google Scholar 

  15. Maharana PK, Jha R (2012) Chalcogenide prism and graphene multilayer based surface plasmon resonance affinity biosensor for high performance. Sens Actuat B: Chem 169:161–166. https://doi.org/10.1016/j.snb.2012.04.051

    Article  CAS  Google Scholar 

  16. Johnson PB, Christy RW (1972) Optical constants of the noble metals. Phys Rev B 6:4370–4379. https://doi.org/10.1103/PhysRevB.6.4370

    Article  ADS  CAS  Google Scholar 

  17. Meshginqalam B, Barvestani J (2018) Aluminum and phosphorene based ultrasensitive SPR biosensor. Opt Mater 86:119–125. https://doi.org/10.1016/j.optmat.2018.10.003

    Article  ADS  CAS  Google Scholar 

  18. Sharma AK, Rajan GBD (2007) Influence of dopants on the performance of a fiber optic surface plasmon resonance sensor. Opt Commun 274:320–326. https://doi.org/10.1016/j.optcom.2007.02.030

    Article  ADS  CAS  Google Scholar 

  19. Popescu VA (2020) Optical fiber-based plasmonic sensors using aluminium oxide insulator. Rom Rep Phys 72:407. https://rrp.nipne.ro/2020/AN2407.pdf

  20. Zhou X, Xiao Z, Luo H, Wen S (2012) Experimental observation of the spin Hall effect of light on a nanometal film via weak measurements. Phys Rev A 85:043809. https://doi.org/10.1103/PhysRevA.85.043809

  21. Laser Thickness Gauge: http://www.goldensen.com/en/show.asp?id=4

  22. ADC and Resolution-Spectrum Instrumentation (https://spectrum-instrumentation.com)

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Funding

Anuj K. Sharma gratefully acknowledges the core research grant (Project no.: CRG/2019/002636) from Science and Engineering Research Board (SERB) India that partially supported this research work.

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Authors and Affiliations

  1. Department of Physics, University Politehnica of Bucharest, Splaiul Independentei 313, 060042, Bucharest, Romania

    Vasile A. Popescu

  2. Physics Division, Department of Applied Sciences, National Institute of Technology Delhi, GT Karnal Road, Delhi, 110036, India

    Anuj K. Sharma

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  1. Vasile A. Popescu
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Both the authors (Vasile A. Popescu and Anuj K. Sharma) contributed equally.

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Correspondence to Vasile A. Popescu.

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Popescu, V.A., Sharma, A.K. High-Performance Plasmonic Sensor Based on Silver, Gold and Graphene Layers for Cancer Cell Detection at 632.8 nm Wavelength with Photonic Spin Hall Effect. Plasmonics 19, 239–249 (2024). https://doi.org/10.1007/s11468-023-01977-9

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