Skip to main content
SpringerLink
Log in

Aqueous Diaminsilver Hydroxide as a Precursor of Pure Silver Nanoparticles for SERS Probing of Living Erythrocytes

  • Published:
Plasmonics Aims and scope Submit manuscript

Abstract

A new effective and simple preparation method of pure metallic hydrosols consisting of silver nanoparticles is proposed using aqueous diaminsilver hydroxide as a precursor freed of special reducing agents, surfactants, or anionic pollutants. The process is driven by NH3 ligand loss and silver complex dissociation followed by silver ion reduction with hydroxyl ions or ammonia itself present in the solution. Self-reduction of aqueous diaminsilver hydroxide occurs for 20–60 min at 90–100 °C in water and results in a wide range of silver nanoparticles, with their sizes dependent on silver complex concentration and reaction time. The pure silver hydrosol is found to attach to a cell membrane without its damage thus allowing measurements of SERS spectra of submembrane hemoglobin inside living erythrocytes.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5

Similar content being viewed by others

References

  1. Evanoff DD Jr, Chumanov G (2005) Synthesis and optical properties of silver nanoparticles and arrays. ChemPhysChem 6:1221–1231

    Article  CAS  Google Scholar 

  2. Lim B, Xia Y (2011) Metal nanocrystals with highly branched morphologies. Angew Chem, Int Ed 50:76–85

    Article  CAS  Google Scholar 

  3. Meng XK, Tang SC, Vongehr S (2010) A review on diverse silver nanostructures. J Mater Sci Technol 2010(26):487–522

    Article  Google Scholar 

  4. Wiley B, Sun Y, Mayers B, Xia Y (2005) Shape-controlled synthesis of metal nanostructures: the case of silver. Chem Eur J 11:454–463

    Article  CAS  Google Scholar 

  5. Zhang Q, Tan YN, Xie J, Lee JY (2009) Colloidal synthesis of plasmonic metallic nanoparticles. Plasmonics 4:9–22

    Article  CAS  Google Scholar 

  6. Alvarez-Puebla RA, Liz-Marzán LM (2010) SERS-based diagnosis and biodetection. Small 2010(6):604–610

    Article  Google Scholar 

  7. Chaloupka K, Malam Y, Seifalian AM (2010) Nanosilver as a new generation of nanoproduct in biomedical applications. Trends Biotechnol 28:580–588

    Article  CAS  Google Scholar 

  8. Brazhe NA, Abdali S, Brazhe AR, Luneva OG, Bryzgalova NY, Parshina EY, Sosnovtseva OV, Maksimov GV (2009) New insight into erythrocyte through in vivo surface-enhanced Raman spectroscopy. Biophys J 97:3206–3214

    Article  CAS  Google Scholar 

  9. Fang J, Liu S, Li Z (2011) Polyhedral silver mesocages for single particle surface-enhanced Raman scattering-based biosensor. Biomaterials 32:4877–4884

    Article  CAS  Google Scholar 

  10. Xu G, Qiao X, Qiu X, Chen J (2010) A facile method to prepare quickly colloidal silver nanoparticles. Rare Metal Mater Eng 39:1532–1535

    Article  Google Scholar 

  11. Daniels JK, Chumanov G (2005) Nanoparticle-mirror sandwich substrates for surface-enhanced Raman scattering. J Phys Chem B 109:17936–17942

    Article  CAS  Google Scholar 

  12. März A, Mönch B, Rösch P, Kiehntopf M, Henkel T, Popp J (2011) Detection of thiopurine methyltransferase activity in lysed red blood cells by means of lab-on-a-chip surface enhanced Raman spectroscopy (LOC-SERS). Anal Bioanal Chem 400:2755–2767

    Article  Google Scholar 

  13. Huang T, Xu X-HN (2010) Synthesis and characterization of tunable rainbow colored colloidal silver nanoparticles using single-nanoparticle plasmonic microscopy and spectroscopy. J Mater Chem 2010(20):9867–9876

    Article  Google Scholar 

  14. Zhang X-Y, Hu A, Zhang T, Lei W, Xue X-J, Zhou Y, Duley WW (2011) Self-assembly of largescale and ultrathin silver nanoplate films with tunable plasmon resonance properties. ACS Nano 5:9082–9092

    Article  CAS  Google Scholar 

  15. Peng S, Sun Y (2010) Synthesis of silver nanocubes in a hydrophobic binary organic solvent. Chem Mater 22:6272–6279

    Article  CAS  Google Scholar 

  16. Pietrobon B, Kitaev V (2008) Photochemical synthesis of monodisperse size-controlled silver decahedral nanoparticles and their remarkable optical properties. Chem Mater 20:5186–5190

    Article  CAS  Google Scholar 

  17. Leopold N, Lendl B (2003) A new method for fast preparation of highly surfaceenhanced Raman 10 scattering (SERS) active silver colloids at room temperature by reduction of silver nitrate with hydroxylamine hydrochloride. J Phys Chem B 107:5723–5727

    Article  CAS  Google Scholar 

  18. Boca SC, Potara M, Gabudean A-M, Juhem A, Baldeck PL, Astilean S (2011) Chitosan-coated triangular silver nanoparticles as a novel class of biocompatible, highly effective photothermal transducers for in vitro cancer cell therapy. Cancer Lett 311:131–140

    Article  CAS  Google Scholar 

  19. Charles DE, Aherne D, Gara M, Ledwith DM, Gun’ko YK, Kelly JM, Blau WJ, Brennan-Fournet ME (2010) Versatile solution phase triangular silver nanoplates for highly sensitive plasmon resonance sensing. ACS Nano 2010(4):55–64

    Article  Google Scholar 

  20. Evanoff DD Jr, Chumanov G (2004) Size-controlled synthesis of nanoparticles. 1. “silver-only” aqueous suspensions via hydrogen reduction. J Phys Chem 108:13948–13956

    Article  CAS  Google Scholar 

  21. Kneipp J, Kneipp H, Wittig B, Kneipp K (2007) One- and two-photon excited optical ph probing for cells using surface-enhanced Raman and hyper-Raman nanosensors. Nano Lett 7:2819–2823

    Article  CAS  Google Scholar 

  22. Yu D, Yam VW-W (2005) Hydrothermal-induced assembly of colloidal silver spheres into various nanoparticles on the basis of HTAB-modified silver mirror reaction. J Phys Chem B 109:5497–503

    Article  CAS  Google Scholar 

  23. Zeng J, Xia X, Rycenga M, Henneghan P, Li Q, Xia Y (2011) Successive deposition of silver on silver nanoplates: lateral versus vertical growth. Angew Chem, Int Ed 50:244–249

    Article  CAS  Google Scholar 

  24. Fan L, Guo R (2008) Growth of dendritic silver crystals in CTAB/SDBS mixed-surfactant solutions, Cryst. Growth Des 8:2150–2156

    Article  CAS  Google Scholar 

  25. Guerrero-Martínez A, Barbosa S, Pastoriza-Santos I, Liz-Marzán LM (2011) Nanostars shine bright for you. Colloid Interface Science 16:118–127

    Article  Google Scholar 

  26. Jena BK, Mishra BK, Bohidar S (2009) Synthesis of branched Ag nanoflowers based on a bioinspired technique: their surface enhanced Raman scattering and antibacterial activity. J Phys Chem C 113:14753–14758

    Article  CAS  Google Scholar 

  27. Liang H, Li Z, Wang W, Wu Y, Xu H (2009) Highly surface-roughened "flower-like" silver nanoparticles for extremely sensitive substrates of surface-enhanced Raman scattering. Adv Mater 21:4614–4618

    Article  CAS  Google Scholar 

  28. Shen XS, Wang GZ, Hong X, Zhu W (2009) Nanospheres of silver nanoparticles: agglomeration, surface morphology control and application as SERS substrates. Phys Chem Chem Phys 11:7450–7454

    Article  CAS  Google Scholar 

  29. Zhang J, Liu H, Zhan P, Wang Z, Ming N (2007) Controlling the growth and assembly of silver nanoprisms. Adv Funct Mater 17:1558–1566

    Article  CAS  Google Scholar 

  30. Cho EC, Cobley CM, Rycenga M, Xia Y (2009) Fine tuning the optical properties of Au–Ag nanocages by selectively etching Ag with oxygen and a water-soluble thiol. J Mater Chem 2009(19):6317–6320

    Article  Google Scholar 

  31. Gallardo OAD, Moiraghi R, Macchione MA, Godoy JA, Pérez MA, Coronado EA, Macagno VA (2012) Silver oxide particles/silver nanoparticles interconversion: susceptibility of forward/backward reactions to the chemical environment at room temperature. RSC Adv 2:2923–2929

    Article  CAS  Google Scholar 

  32. Ho C-M, Yau SK-W, Lok C-N, So M-H, Che C-M (2010) Oxidative dissolution of silver nanoparticles by biologically relevant oxidants: a kinetic and mechanistic study. Chem Asian J 5:285–293

    Article  CAS  Google Scholar 

  33. Sun Y, Xia Y (2002) Shape-controlled synthesis of gold and silver nanoparticles. Science 2002(298):2176

    Article  Google Scholar 

  34. Coskun S, Aksoy B, Unalan HE (2011) Polyol synthesis of silver nanowires: an extensive parametric study. Cryst Growth Des 11:4963–4969

    Article  CAS  Google Scholar 

  35. Chen D, Qiao X, Qiu X, Chen J, Jiang R (2010) Convenient, rapid synthesis of silver nanocubes and nanowires via a microwave-assisted polyol method. Nanotechnology 21:025607

    Article  Google Scholar 

  36. Liang H, Yang H, Wang W, Li J, Xu H (2009) High-yield uniform synthesis and microstructuredetermination of rice-shaped silver nanocrystals. J Am Chem Soc 131:6068–6069

    Article  CAS  Google Scholar 

  37. Luo X, Li Z, Yuana C, Chen Y (2011) Polyol synthesis of silver nanoplates: The crystal growth mechanism based on a rivalrous adsorption. Mater Chem Phys 128:77–82

    Article  CAS  Google Scholar 

  38. Wood BR, Caspers P, Puppels GJ, Pandiancherri S, Mc-Naughton D (2007) Resonance Raman spectroscopy of red blood cells using near-infrared laser excitation. Anal Bioanal Chem 387:1691–1703

    Article  CAS  Google Scholar 

  39. Semenova AA, Goodilin EA, Brazhe NA, Ivanov VK, Baranchikov AE, Lebedev VA, Goldt AE, Sosnovtseva OV, Savilov SV, Egorov AV, Brazhe AR, Parshina EY, Luneva OG, Maksimov GV, Tretyakov YD (2012) Planar SERS nanostructures with stochastic silver ring morphology for biosensor chips. J Mater Chem 22:24530–24544

    Google Scholar 

  40. Jiang XC, Xiong SX, Tian ZA, Chen CY, Chen WM, Yu AB (2011) Twinned structure and growth of V-shaped silver nanowires generated by a polyol-thermal approach. J Phys Chem C 125:1800

    Article  Google Scholar 

  41. Tomellini M (2011) Impact of soft impingement on the kinetics of diffusion-controlled growth of immiscible alloys Comput. Mater Sci 50:2371–2379

    CAS  Google Scholar 

  42. Kiran MS, Itoh T, Yoshida K, Kawashima N, Biju V, Ishikawa M (2010) Selective detection of HbA1c using surface enhanced resonance Raman spectroscopy Anal. Chem 82:1342–1348

    Google Scholar 

  43. Mahato M, Pal P, Tah B, Ghosh M, Talapatra GB (2011) Study of silver nanoparticle–hemoglobin interaction and composite formation Colloids and Surfaces. B: Biointerfaces 88:141–149

    CAS  Google Scholar 

  44. Xu H, Bjerneld EJ, Käll M, Bӧrjesson L (1999) Spectroscopy of single hemoglobin molecules by surface enhanced Raman scattering. Phys Rev Lett 83:4357–4360

    Article  CAS  Google Scholar 

  45. Shaklai N, Yguerabide J, Ranney HM (1977) Interaction of hemoglobin with red blood cell membranes as shown by a fluorescent chromophore. Biochemistry 1977(16):5585–5592

    Article  Google Scholar 

  46. Stein P, Burke JM, Spiro TG (1975) Structural interpretation of heme protein resonance Raman frequencies. Preliminary normal coordinate analysis results. J Am Chem Soc 97:2304–2305

    Article  CAS  Google Scholar 

  47. Tom RT, Samal AK, Sreeprasad TS, Pradeep T (2007) Hemoprotein bioconjugates of Au and Ag nanoparticles and Au nanorods. Langmuir 23:1320–1325

    Article  CAS  Google Scholar 

  48. De Luca AC, Rusciano G, Ciancia R, Martinelli V, Pesce G, Rotoli B, Selvaggi L, Sasso A (2008) Spectroscopical and mechanical characterization of normal and thalassemic red blood cells by Raman tweezers. Optics Express 16:7943–7957

    Article  Google Scholar 

  49. Bernhardt I, Ellory JC (eds) (2003) Red cell membrane transport in health and disease. Springer, New York

    Google Scholar 

  50. Brazhe NA, Parshina EY, Khabatova VV, Semenova AA, Brazhe AR, Yusipovich AI, Sarycheva AS, Churin AA, Goodilin EA, Maksimov GV, Sosnovtseva OV (2013) Tuning SERS for living erythrocytes: focus on nanoparticle size and plasmon resonance position. J Raman Spectrosc 44:686–694

    Google Scholar 

  51. Parshina EY, Sarycheva AS, Yusipovich AI, Brazhe NA, Goodilin EA, Maksimov GV (2013) Combined Raman and atomic force microscopy study of hemoglobin distribution inside erythrocytes and nanoparticle localization on the erythrocyte surface. Laser Phys Lett 10:075607

    Google Scholar 

Download references

Acknowledgments

This work was supported by the Russian Foundation for Basic Research (contract 13-03-12190), the Development Program of MSU and The Danish Council for Independent Research | Natural Sciences. Authors thanks O. Sosnovtseva (Copenhagen University) and S. Savilov (MSU) for their help with the experiments and their fruitful discussions.

Author information

Authors and Affiliations

  1. Department of Materials Science, Moscow State University, Lenin Hills, Moscow, 119991, Russia

    Anna A. Semenova, Vladimir K. Ivanov & Eugene A. Goodilin

  2. Faculty of Biology, Moscow State University, Moscow, 119991, Russia

    Nadezda A. Brazhe, Evgeniya Y. Parshina & Georgy V. Maksimov

  3. Kurnakov Institute of General and Inorganic Chemistry of RAS, Leninskiy prospect, Moscow, 119991, Russia

    Vladimir K. Ivanov

  4. Faculty of Chemistry, Moscow State University, Moscow, 119991, Russia

    Eugene A. Goodilin

Authors
  1. Anna A. Semenova
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Nadezda A. Brazhe
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Evgeniya Y. Parshina
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Vladimir K. Ivanov
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Georgy V. Maksimov
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Eugene A. Goodilin
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Eugene A. Goodilin.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Semenova, A.A., Brazhe, N.A., Parshina, E.Y. et al. Aqueous Diaminsilver Hydroxide as a Precursor of Pure Silver Nanoparticles for SERS Probing of Living Erythrocytes. Plasmonics 9, 227–235 (2014). https://doi.org/10.1007/s11468-013-9616-9

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11468-013-9616-9

Keywords

Search

Navigation