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Progress of transition metal-catalyzed cross-coupling mediated by PyBroP

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  • Organic Chemistry
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Chinese Science Bulletin

Abstract

In the transition metal-catalyzed cross-coupling reactions, phenol and enol derivatives activated by phosphorus groups are very important electrophiles. This kind of compounds has the advantages of easy preparation, great stability, and producing more benign phosphorus by-products. The present work provides a comprehensive review of the advances made over the past several decades in this area. Cross-coupling reactions mediated by PyBroP are first surveyed, then two types of recently developed transition metal-catalyzed reactions, i.e., Pd-catalyzed and Ni-catalyzed reactions, and the corresponding mechanisms are discussed. Finally, future directions are analyzed.

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Acknowledgments

This work was supported by the Public Welfare Technology Applied Project of Lishui City (2012JYZB32).

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Authors and Affiliations

  1. College of Science, Changchun Institute of Technology, Changchun, 130012, China

    Guojun Chen

  2. Vascular Surgery, The Third Hospital of Jilin University, Changchun, 130033, China

    Jianshi Du

Authors
  1. Guojun Chen
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  2. Jianshi Du
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Correspondence to Guojun Chen or Jianshi Du.

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Chen, G., Du, J. Progress of transition metal-catalyzed cross-coupling mediated by PyBroP. Chin. Sci. Bull. 59, 1942–1949 (2014). https://doi.org/10.1007/s11434-014-0239-0

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