Abstract
A convenient, economical and green approach to the synthesis of 1H-indazolo[1,2-b]phthalazine-1,6,11-trione derivatives has been achieved via a one-pot protocol using phthalhydrazide, a cyclic-β-diketone and an aldehyde in the presence of a ceric ammonium nitrate catalyst in polyethylene glycol. The simple work up, mild conditions, excellent yields, inexpensive and non-toxic catalyst and simple solvent recyclability render this protocol both attractive and economically viable.
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Mazaahir, K., Ritika, C. & Anwar, J. Efficient CAN catalyzed synthesis of 1H-indazolo[1,2-b] phthalazine-1,6,11-triones: An eco-friendly protocol. Chin. Sci. Bull. 57, 2273–2279 (2012). https://doi.org/10.1007/s11434-012-5081-7
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DOI: https://doi.org/10.1007/s11434-012-5081-7