Skip to main content
SpringerLink
Log in

Targeted nanoparticles for precise cancer therapy

  • Insight
  • Published:
Science China Life Sciences Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  • Chen, J., Liu, L., Motevalli, S.M., Wu, X., Yang, X.H., Li, X., Han, L., Magrini, A., Guo, W., Chang, J., et al. (2018). Light-triggered retention and cascaded therapy of albumin-based theranostic nanomedicines to alleviate tumor adaptive treatment tolerance. Adv Funct Mater 28, 1707291.

    Article  Google Scholar 

  • Chen, Q., Hu, Q., Dukhovlinova, E., Chen, G., Ahn, S., Wang, C., Ogunnaike, E.A., Ligler, F.S., Dotti, G., and Gu, Z. (2019). Photothermal therapy: photothermal therapy promotes tumor infiltration and antitumor activity of CAR T cells. Adv Mater 31, 1970166.

    Article  Google Scholar 

  • Chen, S., and Liang, X.J. (2018). Nanobiotechnology and nanomedicine: small change brings big difference. Sci China Life Sci 61, 371–372.

    Article  Google Scholar 

  • Du, Y., Liu, X., Liang, Q., Liang, X.J., and Tian, J. (2019). Optimization and design of magnetic ferrite nanoparticles with uniform tumor distribution for highly sensitive MRI/MPI performance and improved magnetic hyperthermia therapy. Nano Lett 19, 3618–3626.

    Article  CAS  Google Scholar 

  • Fan, W., Qi, Y., Wang, R., Xu, C., Zhao, N., and Xu, F.J. (2018). Calcium carbonate-methylene blue nanohybrids for photodynamic therapy and ultrasound imaging. Sci China Life Sci 61, 483–491.

    Article  CAS  Google Scholar 

  • Gong, N., Ma, X., Ye, X., Zhou, Q., Chen, X., Tan, X., Yao, S., Huo, S., Zhang, T., Chen, S., et al. (2019). Carbon-dot-supported atomically dispersed gold as a mitochondrial oxidative stress amplifier for cancer treatment. Nat Nanotechnol 14, 379–387.

    Article  CAS  Google Scholar 

  • Gong, N., Teng, X., Li, J., and Liang, X.J. (2019). Antisense oligonucleotide-conjugated nanostructure-targeting lncRNA MALAT1 inhibits cancer metastasis. ACS Appl Mater Interfaces 11, 37–42.

    Article  CAS  Google Scholar 

  • Gong, N., Zhang, Y., Zhang, Z., Li, X., and Liang, X.J. (2019). Functional nanomaterials optimized to circumvent tumor immunological tolerance. Adv Funct Mater 29, 1806087.

    Article  Google Scholar 

  • Gu, F.X., Karnik, R., Wang, A.Z., Alexis, F., Levy-Nissenbaum, E., Hong, S., Langer, R.S., and Farokhzad, O.C. (2007). Targeted nanoparticles for cancer therapy. Nano Today 2, 14–21.

    Article  Google Scholar 

  • Hameed, S., Bhattarai, P., and Dai, Z. (2018). Nanotherapeutic approaches targeting angiogenesis and immune dysfunction in tumor microenvironment. Sci China Life Sci 61, 380–391.

    Article  CAS  Google Scholar 

  • Haume, K., Rosa, S., Grellet, S., Śmialek, M.A., Butterworth, K.T., Solov’yov, A.V., Prise, K.M., Golding, J., and Mason, N.J. (2016). Gold nanoparticles for cancer radiotherapy: a review. Cancer Nano 7, 8.

    Article  Google Scholar 

  • Lu, Y., Aimetti, A.A., Langer, R., and Gu, Z. (2017). Bioresponsive materials. Nat Rev Mater 2, 16075.

    Article  CAS  Google Scholar 

  • Mi, Y., Shao, Z., Vang, J., Kaidar-Person, O., and Wang, A.Z. (2016). Application of nanotechnology to cancer radiotherapy. Cancer Nano 7, 11.

    Article  Google Scholar 

  • Pan, X., Wang, H., Wang, S., Sun, X., Wang, L., Wang, W., Shen, H., and Liu, H. (2018). Sonodynamic therapy (SDT): a novel strategy for cancer nanotheranostics. Sci China Life Sci 61, 415–426.

    Article  Google Scholar 

  • Tuguntaev, R.G., Chen, S., Eltahan, A.S., Mozhi, A., Jin, S., Zhang, J., Li, C., Wang, P.C., and Liang, X.J. (2017). P-gp inhibition and mitochondrial impairment by dual-functional nanostructure based on vitamin E derivatives to overcome multidrug resistance. ACS Appl Mater Interfaces 9, 16900–16912.

    Article  CAS  Google Scholar 

  • Wang, S., Liu, X., Chen, S., Liu, Z., Zhang, X., Liang, X.J., and Li, L. (2019). Regulation of Ca2+ signaling for drug-resistant breast cancer therapy with mesoporous silica nanocapsule encapsulated doxorubicin/siRNA cocktail. ACS Nano 13, 274–283.

    Article  CAS  Google Scholar 

  • Xiang, J., Wu, B., Zhou, Z., Hu, S., Piao, Y., Zhou, Q., Wang, G., Tang, J., Liu, X., and Shen, Y. (2018). Synthesis and evaluation of a paclitaxel-binding polymeric micelle for efficient breast cancer therapy. Sci China Life Sci 61, 436–447.

    Article  CAS  Google Scholar 

  • Zhang, H., Liu, X.L., Zhang, Y.F., Gao, F., Li, G.L., He, Y., Peng, M.L., and Fan, H.M. (2018). Magnetic nanoparticles based cancer therapy: current status and applications. Sci China Life Sci 61, 400–414.

    Article  CAS  Google Scholar 

  • Zhang, T., Huang, Y., Ma, X., Gong, N., Liu, X., Liu, L., Ye, X., Hu, B., Li, C., Tian, J.H., et al. (2018). Fluorinated oligoethylenimine nanoassemblies for efficient siRNA-mediated gene silencing in serum-containing media by effective endosomal escape. Nano Lett 18, 6301–6311.

    Article  CAS  Google Scholar 

  • Zhang, X.D., Chen, J., Luo, Z., Wu, D., Shen, X., Song, S.S., Sun, Y.M., Liu, P.X., Zhao, J., Huo, S., et al. (2014). Enhanced tumor accumulation of sub-2 nm gold nanoclusters for cancer radiation therapy. Adv Healthcare Mater 3, 133–141.

    Article  CAS  Google Scholar 

  • Zhang, Y., Huang, F., Ren, C., Liu, J., Yang, L., Chen, S., Chang, J., Yang, C., Wang, W., Zhang, C., et al. (2019). Enhanced radiosensitization by gold nanoparticles with acid-triggered aggregation in cancer radiotherapy. Adv Sci 6, 1801806.

    Article  Google Scholar 

Download references

Acknowledgements

This work was supported by the National Natural Science Foundation key project (31630027 and 31430031) and NSFC-DFG project (31761133013).

Author information

Authors and Affiliations

  1. CAS Center for Excellence in Nanoscience, CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Chinese Academy of Sciences, National Center for Nanoscience and Technology of China, Beijing, 100190, China

    Jinjin Wang, Yongchao Wang, Ruifang Wang & Xing-Jie Liang

  2. University of Chinese Academy of Sciences, Beijing, 100049, China

    Jinjin Wang, Ruifang Wang & Xing-Jie Liang

  3. State Key Laboratory of Natural Medicines and Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases, Center of Advanced Pharmaceutics and Biomaterials, Center of Drug Discovery, Institute of Pharmaceutical Sciences, China Pharmaceutical University, Nanjing, 210009, China

    Yongchao Wang & Xiaoxuan Liu

  4. Epilepsy Department, Beijing Chaoyang Emergency Medical Center, Beijing, 100122, China

    Shouwen Zhang

Authors
  1. Jinjin Wang
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Yongchao Wang
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Ruifang Wang
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Shouwen Zhang
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Xiaoxuan Liu
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Xing-Jie Liang
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Xing-Jie Liang.

Ethics declarations

Compliance and ethics The author(s) declare that they have no conflict of interest.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Wang, J., Wang, Y., Wang, R. et al. Targeted nanoparticles for precise cancer therapy. Sci. China Life Sci. 62, 1392–1395 (2019). https://doi.org/10.1007/s11427-019-9824-0

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11427-019-9824-0

Search

Navigation