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Dr. Michael Xi Zhu is professor of Department of Integrative Biology and Pharmacology, McGovern Medical School, the University of Texas Health Science Center at Houston. He received his B.S. degree in Biology from Fudan University, China, in 1984, and his M.S. and Ph.D. degrees from University of Houston, USA, in 1988 and 1991, respectively. He had his postdoctoral training in Cellular and Molecular Biology from 1991–1994 at Baylor College of Medicine. He then worked as an Assistant Researcher in the Department of Anesthesiology, UCLA, from 1994 to 1997. In autumn of 1997, he went to the Ohio State University to build his own lab and rose from the rank of Assistant Professor to Full Professor in the Department of Neuroscience there. In 2010, he moved to his current position at the University of Texas-Houston. Dr. Zhu’s research interests include several aspects of cell signaling, especially those that involve heterotrimeric G proteins and ion channels that affect Ca2+ signaling. He has published more than 130 research papers, reviews, and monographs on these topics and delivered lectures at many international conferences and symposia. Dr. Zhu’s main contributions include identification and characterization of multiple Transient Receptor Potential Canonical (TRPC) channels in mammalian species and determination of the molecular identity of endolysosomal Ca2+ release channels activated by the Ca2+ mobilizing messenger, nicotinic acid adenine dinucleotide phosphate (NAADP). Dr. Zhu serves as a Series Editor of the CRC Methods in Signal Transduction Book Series, an Associate Editor of Journal of Cellular Physiology and editorial board members of Pflügers Archiv European Journal of Physiology, Biophysics Reports and Molecular Pharmacology. He was a regular member of the US NIH Molecular and Integrative Signal Transduction study section from 2010–2014. Dr. Zhu is serving as a co-chair for organizing the 2nd Gordon Research Conference on Organellar Channels and Transporters, to be held in Vermont, USA, in summer 2017. He served as the vice chair of the 2nd International Conference on Ion channels in Technology and Drug Discovery held in Harbin, 2009, an oversea chair of the 2010 symposium for Chinese Neuroscientists Worldwide held in Nanchang, a scientific committee chair of the 17th International Symposium on Ca2+-Binding Proteins and Ca2+ Function in Health and Disease held in Beijing, 2011, the chair of the 3rd International Ion Channel Conference-Ion Channels: Structure, Function & Therapeutics held in Shanghai, 2011, the oversea chair for the 9th Chinese Symposium on Calcium Signaling in Huangshan, 2012.
Dr. Biguang Tuo is professor at Zunyi Medical College, who works in Affiliated Hospital of Zunyi Medical College, where he serves as chief of Department of Gastroenterology and Institute of Digestive Diseases of Guizhou Province. Dr. Tuo is a chief of Guizhou Gastroenterology Association, China, and a member of American Gastroenterology Association. Dr. Tuo earned his bachelor’s degree in Medicine from Guiyang Medical College, China, and a master’s degree in Medicine from Peking University Healthy Science Center, Beijing, China. He earned his Ph.D. in Gastroenterology from Hannover Medical School, Germany, and finished his postdoctoral training in the University of California, San Diego, USA, where he undertook studies in ion channels and intestinal secretion. Currently, his research focuses on ion channels and development and progress of tumor, especially calcium signaling and development and progress of hepatocellular carcinoma. Dr. Tuo is a co-Chair of the 11th Symposium on Calcium Signaling in China, Zunyi, 2016. p ]Dr. Jenny Jie Yang is a Distinguished University Professor of Chemistry and Associate Director of the Center for Diagnostics and Therapeutics at Georgia State University. She received her Ph.D. in Biochemistry at the Florida State University in 1992. She was a Research Fellow at Syntex Discovery Research (Roche Biosciences). From 1993 to 1995, she was an Oxford Center for Molecular Sciences (OCMS) Research Fellow at the University of Oxford, UK. She was also a Harford Research Fellow of Molecular Biophysics and Biochemistry at Yale University. In 1997, Dr. Yang joined the faculty at the Chemistry Department of Georgia State University, where she was promoted to full professor in 2006. Dr. Yang received the Outstanding Junior Faculty Award, the Outstanding Faculty Achievement Award, and the Alumni Distinguished Faculty Achievement Award at GSU. Dr. Yang’s laboratory applies protein design and engineering approaches to understand molecular basis of diseases, modulate calcium signaling, and create novel reagents and tools for research, diagnostics and disease treatment. Her research on Calciomics enables visualization of the roles of calcium in extracellular, intracellular Ca2+ signaling & cell-cell communication under both biological and pathological processes. Key determinants for calcium binding, selectivity and conformational changes have been identified by design and analysis of calcium- binding proteins. Dr. Yang’s research group has designed Ca2+ and enzyme sensors for monitoring rapid cellular signaling events. Her research team has also developed novel classes of protein reagents including MRI contrast agent (ProCA) to enable non-invasive early and precision detection of various types of cancers and fibrosis and created protein drug candidates with improved therapeutic effects. The research activities in Dr. Yang’s laboratory lead to many important inventions including over 120 publications and > 20 patent applications. She has mentored ~110 trainees. Dr. Yang is a co-Chair of the 11th Symposium on Calcium Signaling in China, Zunyi, 2016.
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Zhu, M.X., Tuo, B. & Yang, J.J. The hills and valleys of calcium signaling. Sci. China Life Sci. 59, 743–748 (2016). https://doi.org/10.1007/s11427-016-5098-2
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DOI: https://doi.org/10.1007/s11427-016-5098-2