Abstract
As a powerful macrocyclic host molecule with unique conformation and cavity structure that are fine-tuned by the bridging nitrogen atoms, methylazacalix[4]pyridine (MACP-4) has been shown to selectively recognize Zn2+ and form stable Zn(II)-MACP-4 complexes both in solid state and solution with an association constant up to 5.97 (logK s). The molecular recognition of Zn(II)-MACP-4 complexes towards various amino acids and anions with different geometry was investigated by using the spectral titration methods and X-ray analysis. The Zn(II)-MACP-4 complex was found to recognize the 17 amino acids tested with the association constant up to 3.97 (logK s). On the other hand, the Zn(II)-MACP-4 complex selectively interacted with anions and the maximum association constant of 3.9 (logK s) was obtained.
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Crystallographic data for MACP-4·1.5ZnI2·I2·H2O (C24H24I5N8-OZn1.5′): Mr = 1173.07, Triclinic, space group P21/m, a = 14.781(3), b = 14.358(3), c = 15.814(3) Å, α = 90.00°, β = 107.87°(3), γ = 90.00°, V = 3194.2(11) Å3, T = 293(2) K, full-matrix least-squares refinement on F 2 converged to R F = 0.1456 [I > 2σ(I)], 0.2065 (all data) and Rw(F 2) = 0.4221 [I > 2σ(I)], 0.4636 (all data), goodness of fit 1.724
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Supported by the National Natural Science Foundation of China (Grant No. 20672115, 20875094 & 20532030), Ministry of Science and Technology of China (Grant No. 2007CB808005), and the Chinese Academy of Sciences
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Gong, H., Wang, D., Huang, Z. et al. Recognition of amino acids and anions by a Zn(II)-methylazacalix[4]pyridine complex. Sci. China Ser. B-Chem. 52, 1639–1645 (2009). https://doi.org/10.1007/s11426-009-0186-9
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DOI: https://doi.org/10.1007/s11426-009-0186-9