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Controllable synthesis Fe3O4@POHABA core-shell nanostructure as high-performance recyclable bifunctional magnetic antimicrobial agent

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Abstract

We demonstrated a method to form magnetic antimicrobial POHABA (poly-N,N′-[(4,5-dihydroxy-1,2-phenylene)bis(methylene)]bisacrylamide)-based core-shell nanostructure by free-radical polymerization of OHABA on the Fe3O4 core surface. The magnetic antimicrobial agent Fe3O4@POHABA can be used in domestic water treatment against bacterial pathogens. The thickness of POHABA shell could be controlled from 10.4 ± 1.2 to 56.3 ± 11.7 nm by the dosage of OHABA. The results of antimicrobial-activity test indicated that POHABA-based core-shell nanostructure had broad-spectrum inhibitory against Gram-negative, Gram-positive bacteria and fungi. The minimum inhibitory concentration (MIC) values of Fe3O4@POHABA nanostructure against Escherichia coli and Bacillus subtilis were both 0.4 mg/mL. Fe3O4@POHABA nanostructures responded to a permanent magnet and were easily recycled. Fe3O4@POHABA nanoparticles retained 100% antimicrobial efficiency for both Gram-negative and Gram-positive bacteria throughout eight recycle procedures.

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Acknowledgements

This work was supported by the National Natural Science Foundation of China (Grant no. 21528501), the HIT Environment and Ecology Innovation Special Funds (HSCJ201617), and the National Key Research and Development Programme (2016YFC0401104).

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Authors and Affiliations

  1. MIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage, State Key Laboratory of Urban Water Resource and Environment, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, 92 West Da-Zhi Street, Harbin, 150001, China

    Zhijia Zhang & Xiaojun Han

  2. State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, 92 West Da-Zhi Street, Harbin, 150001, China

    Defeng Xing & Xin Zhao

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  1. Zhijia Zhang
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  2. Defeng Xing
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  3. Xin Zhao
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  4. Xiaojun Han
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Correspondence to Xiaojun Han.

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Zhang, Z., Xing, D., Zhao, X. et al. Controllable synthesis Fe3O4@POHABA core-shell nanostructure as high-performance recyclable bifunctional magnetic antimicrobial agent. Environ Sci Pollut Res 24, 19011–19020 (2017). https://doi.org/10.1007/s11356-017-9535-y

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