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Sleep-disordered breathing in patients with neuromuscular disease

  • Sleep Breathing Physiology and Disorders • Review
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Abstract

Sleep-disordered breathing (SDB) is relatively common in general population as well as in patients with neuromuscular disease. SDB comprises a wide spectrum of disorders varying from simple snoring to complete closure of the upper airway as seen in obstructive sleep apnoea (OSA). It includes also other disorders like prolonged hypoxemia, hypoventilation, and central sleep apnoea (CSA). Neuromuscular diseases (NMD) form a group of disorders that can cause significant reduction in the quality and span of life. The involvement of respiratory system in the context of these disorders is the most serious complication, and it is considered as the leading cause of death in those patients. NMD can affect ventilation, cough, swallowing, and phonation. The involvement of respiratory muscles makes NMD patients vulnerable to sleep-disordered breathing with a significant prevalence of SDB among such patients.

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Authors and Affiliations

  1. Damascus University, Damascus, Syria

    Mohamad Ammar Albdewi

  2. Université Catholique de Louvain, Brussels, Belgium

    Mohamad Ammar Albdewi

  3. Service de Pneumologie, Cliniques Universitaires Saint-Luc, Av. Hippocrate 10, 1200, Brussels, Belgium

    Mohamad Ammar Albdewi

  4. Institut de Recherche Expérimentale et Clinique (IREC), Pôle de Pneumologie, ORL & Dermatologie, Université Catholique de Louvain, Brussels, Belgium

    Giuseppe Liistro

  5. Service de Pneumologie, Epreuves Fonctionnelles Respiratoires, Centre de Médecine du Sommeil, Cliniques Universitaires Saint-Luc, Av. Hippocrate 10, 1200, Brussels, Belgium

    Giuseppe Liistro

  6. Department of Neurology-Center for Refractory Epilepsy, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Av. Hippocrate 10, 1200, Brussels, Belgium

    Riëm El Tahry

  7. Department of Pneumology- Sleep Laboratory, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Av. Hippocrate 10, 1200, Brussels, Belgium

    Riëm El Tahry

  8. Cleveland Clinic Epilepsy Center, Cleveland, OH, 44195, USA

    Riëm El Tahry

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  1. Mohamad Ammar Albdewi
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  2. Giuseppe Liistro
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Correspondence to Mohamad Ammar Albdewi.

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Albdewi, M.A., Liistro, G. & El Tahry, R. Sleep-disordered breathing in patients with neuromuscular disease. Sleep Breath 22, 277–286 (2018). https://doi.org/10.1007/s11325-017-1538-x

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  • DOI: https://doi.org/10.1007/s11325-017-1538-x

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