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MR appearance of a rare ameloblastic fibroma with formation of dental hard tissues with histopathologic correlation: a case report

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Abstract

An ameloblastic fibroma with formation of dental hard tissues, which the classical name is ameloblastic fibro-odontoma (AFO), is a rare type of mixed odontogenic tumor. An 8-year-old boy was diagnosed with AFO, with an inhomogeneous high signal within the lesion shown by T2-weighted magnetic resonance imaging (MRI). Computed tomography (CT) imaging revealed a unilocular low CT value area of 24 × 19 × 26 mm with buccolingual bony expansion and cortical bone thinning on the left side of the mandible including the crown of the mandibular left second molar. In addition, multiple calcified bodies were detected within the lesion, one of which had a CT value of approximately 2200 HU, equivalent to that of enamel. MRI indicated the lesion to be sized 24 × 19 × 25 mm along with buccolingual bony expansion in the left side of the mandible. Additionally, the lesion showed an internal inhomogeneous high signal, while a portion had an especially high signal in T2-weighted images. That particularly high signal area coincided with the nodular growth area of mucus-rich mesenchymal components without the epithelial component in histopathology findings. The particularly high signal revealed by T2-weighted imaging could be attributed to the mucus-rich component. MRI was found useful for revealing differences in the internal histopathological properties of an AFO in our patient.

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Authors and Affiliations

  1. Department of Oral and Maxillofacial Radiology, Osaka University Graduate School of Dentistry, 1-8 Yamadaoka, Suita, Osaka, 565-0871, Japan

    Makihito Hamamoto, Hiroaki Shimamoto, Sven Kreiborg, Sanjay M. Mallya, Fan-pei Gloria Yang & Shumei Murakami

  2. Clinical Laboratory, Osaka University Dental Hospital, 1-8 Yamadaoka, Suita, Osaka, 565-0871, Japan

    Kaori Oya & Yasuo Fukuda

  3. Department of Pediatric Dentistry and Clinical Genetics, School of Dentistry, Faculty of Health and Medical Sciences, University of Copenhagen, Nørre Allé 20, 2200, Copenhagen, Denmark

    Sven Kreiborg

  4. 3D Craniofacial Image Research Laboratory School of Dentistry, University of Copenhagen, Copenhagen, Denmark

    Sven Kreiborg

  5. Centre of Head and Orthopedics, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark

    Sven Kreiborg

  6. Department of Applied Mathematics and Computer Science, Technical University of Denmark, Nørre Allé 20, 2200, Copenhagen, Denmark

    Sven Kreiborg

  7. Section of Oral and Maxillofacial Radiology, UCLA School of Dentistry, 10833 Le Conte Ave., Los Angeles, CA, 90095-1668, USA

    Sanjay M. Mallya

  8. Department of Foreign Languages and Literature, National Tsing Hua University, No.101, Section 2, Guangfu Rd., East District, Hsinchu, 300013, Taiwan

    Fan-pei Gloria Yang

  9. Center for Cognition and Mind Sciences, National Tsing Hua University, No.101, Section 2, Guangfu Rd., East District, Hsinchu, 300013, Taiwan

    Fan-pei Gloria Yang

Authors
  1. Makihito Hamamoto
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  2. Hiroaki Shimamoto
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  3. Kaori Oya
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  4. Yasuo Fukuda
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  5. Sven Kreiborg
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  6. Sanjay M. Mallya
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  7. Fan-pei Gloria Yang
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  8. Shumei Murakami
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Correspondence to Hiroaki Shimamoto.

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All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (Osaka University Graduate School of Dentistry) and with the Helsinki Declaration of 1975, as revised in 2008 (5).

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Informed consent was obtained from the patient for being included in the study.

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Hamamoto, M., Shimamoto, H., Oya, K. et al. MR appearance of a rare ameloblastic fibroma with formation of dental hard tissues with histopathologic correlation: a case report. Oral Radiol 39, 220–224 (2023). https://doi.org/10.1007/s11282-022-00649-4

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  • DOI: https://doi.org/10.1007/s11282-022-00649-4

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