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Recurrent malignant melanoma of the palate successfully treated by gamma knife radiosurgery

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An Erratum to this article was published on 27 March 2013

Abstract

The prognosis of oral malignant melanoma is reported to be extremely poor. In this report, a patient with recurrent oral melanoma in the skull base that was successfully treated by gamma knife radiosurgery (GKS) is described. A 53-year-old man was referred with a chief complaint of a mass of the hard palate. The histological diagnosis of a biopsy specimen was malignant melanoma. He underwent a wide local resection with bilateral neck dissection, followed by immunochemotherapy with DAV-Feron. At 13 months postoperatively, a recurrent tumor was found in the posterior lower region of the nasal septum. The patient underwent resection of the lesion, followed by immunochemotherapy with DAC-Tam-Feron. However, at 9 months after the last chemotherapy, local recurrence occurred again in the skull base, and he underwent GKS. The recurrent tumor disappeared completely and he is well with no signs of recurrence or metastasis at 57 months after GKS.

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The authors declare that they have no conflict of interest.

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Authors and Affiliations

  1. Department of Clinical Oral Oncology, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8588, Japan

    Shin-ichi Yamada, Souichi Yanamoto, Akiko Kawakita, Goro Kawasaki & Masahiro Umeda

  2. Department of Oral Pathology and Bone Metabolism, Unit of Translational Medicine, Course of Medical and Dental Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan

    Shuichi Fujita & Tohru Ikeda

  3. Department of Oral and Maxillofacial Surgery, Omura Municipal Hospital, Omura, Japan

    Takemitsu Matsuo

Authors
  1. Shin-ichi Yamada
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  2. Souichi Yanamoto
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  3. Akiko Kawakita
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  4. Goro Kawasaki
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  5. Shuichi Fujita
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  6. Tohru Ikeda
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  7. Takemitsu Matsuo
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  8. Masahiro Umeda
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Correspondence to Shin-ichi Yamada.

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Yamada, Si., Yanamoto, S., Kawakita, A. et al. Recurrent malignant melanoma of the palate successfully treated by gamma knife radiosurgery. Oral Radiol 29, 170–175 (2013). https://doi.org/10.1007/s11282-012-0120-2

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  • DOI: https://doi.org/10.1007/s11282-012-0120-2

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