Design and wet-laboratory implementation of reliable end-to-end molecular communication
- 438 Downloads
This paper describes a novel design and wet laboratory implementation of reliable end-to-end molecular communication. In the reliable end-to-end molecular communication described in this paper, source and destination bio-nanomachines exchange molecular packets through intermediate bio-nanomachines that are capable of packet replication. A source bio-nanomachine forms a molecular packet and transmits the molecular packet into the environment. An intermediate bio-nanomachine detects a molecular packet and produces its copies through packet replication. A destination bio-nanomachine, upon reception of a molecular packet, produces an acknowledgment molecular packet and transmits back to the source bio-nanomachine. This paper describes how the reliable end-to-end molecular communication can be biochemically implemented with RNA (ribonucleic acid) molecules and artificial cell systems. It also describes a simulation-based performance evaluation study showing the impact of model parameters on propagation delay in the reliable end-to-end molecular communication.
KeywordsMolecular communication Bio-nanomachine Packet replication Ack transmission Artificial cell RNA (ribonucleic acid)
This work was supported through the Osaka University Humanware Innovation Program, a Leading Graduate School Program by the Japan Society of the Promotion of Science. This work was also supported by JSPS KAKENHI Grant Number JP25240011.
- 1.Ahmadzadeh, A., Noel, A., & Schober, R. (2014). Analysis and design of two-hop diffusion-based molecular communication networks. In: IEEE global communications conference (GLOBECOM 2014) (pp. 2820–2825).Google Scholar
- 7.Eckford, A.W., Farsad, N., Hiyama, S., & Moritani, Y. (2010). Microchannel molecular communication with nanoscale carriers: Brownian motion versus active transport. In: Proceedings of the IEEE international conference on nanotechnology (pp. 854–858).Google Scholar
- 8.Eckford, A.W., Furubayashi, T., & Nakano, T. (2016). RNA as a nanoscale data transmission medium: Error analysis. In: IEEE international conference on nanotechnology (IEEE NANO 2016). Google Scholar
- 9.Farsad, N., Yilmaz, H.B., Eckford, A., Chae, C.B., & Guo, W. (2016). A comprehensive survey of recent advancements in molecular communication. IEEE Communications Surveys and Tutorials, 18(3), 1887–1919.Google Scholar
- 12.Furubayashi, T., Nakano, T., Eckford, A., & Yomo, T. (2015). Reliable end-to-end molecular communication with packet replication and retransmission. In: IEEE global communications conference (GLOBECOM 2015). Google Scholar
- 15.Hiyama, S., Moritani, Y., Suda, T., Egashira, R., Enomoto, A., Moore, M., et al. (2005). Molecular communication. Proceedings of the NSTI Nanotechnology Conference, 3, 392–395.Google Scholar
- 21.Nakano, T., & Shuai, J. (2011). Repeater design and modeling for molecular communication networks. In: Proceedings of the 2011 IEEE INFOCOM workshop on molecular and nanoscale communications (pp. 501–506) Google Scholar
- 24.Ortiz, M. E., & Endy, D. (2012). Engineered cell-cell communication via DNA messaging. Journal of Biological Engineering, 6(16), 1.Google Scholar
- 28.Rose, C., & Mian, I.S. (2015). A fundamental framework for molecular communication channels: Timing & payload. In: 2015 IEEE internatinoal conference on communications (ICC 2015) (pp. 1043–1048)Google Scholar