A divergent rotavirus I was detected using viral metagenomics in the feces of a cat with diarrhea. The eleven segments of rotavirus I strain Felis catus encoded non-structural and structural proteins with amino acid identities ranging from 25 to 79% to the only two currently sequenced members of that viral species both derived from canine feces. No other eukaryotic viral sequences nor bacterial and protozoan pathogens were detected in this fecal sample suggesting the involvement of rotavirus I in feline diarrhea.
KeywordsRotavirus Feces Diarrhea Cat Metagenomics
We acknowledge support from IDEXX Laboratories, Inc.
TP, CL, and ED: designed the study; TP and CL: performed experiments; TP, CL, and ED: wrote the manuscript; and CL and RC: provided clinical information and samples.
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Conflict of interest