Abstract
Prompt diagnosis and treatment with corticosteroids of the tubulointerstitial nephritis with uveitis (TINU) syndrome may assist in the preservation of renal function. We present a case illustrating the characteristic clinical features of this syndrome. Gallium scintigraphy assisted in the diagnosis and management of this case, which was complicated by relapsing pyelonephritis.
Similar content being viewed by others
References
RS Dobrin RL Vernier AL. Fisch (1975) ArticleTitleAcute eosinophilic interstitial nephritis and renal failure with bone marrow-lymph node granulomas and anterior uveitis Am J Med 59 325–333 Occurrence Handle10.1016/0002-9343(75)90390-3 Occurrence Handle1163543
P Vanhaesebrouk D Carton C De Bel M Praet W. Proesmans (1985) ArticleTitleAcute tubulo-interstitial nephritis and uveitis syndrome (TINU syndrome) Nephron 40 418–422 Occurrence Handle4022210
M Burnier P Jaeger M Campiche JP. Wauters (1986) ArticleTitleIdiopathic acute interstitial nephritis and uveitis in the adult: report of 1 case and review of the literature Am J Nephrol 6 312–315 Occurrence Handle3535505
U Gafter M Ben-Basat D Zevin L Komlos H Savir J. Levi (1986) ArticleTitleAnterior uveitis, a presenting symptom in acute interstitial nephritis Nephron 42 249–251 Occurrence Handle3484809
P Cacoub G Dearay P Le Hoang A Beaumelou H Beaufils F Groc Particlede F Rousselie C Jouanneau C. Jacobs (1989) ArticleTitleIdiopathic acute interstitial nephritis associated with anterior uveitis in adults Clin Nephrol 31 307–310 Occurrence Handle2665992
S Kenouche D Belghiti P Di Costanzo JP. Mery (1989) ArticleTitleUn nouveau syndrome: Les nephropathies interstitielles augues avec uveite Ann Med Interne 140 169–172
N Itami Y Akutsu K Yasoshima H Tochimaru Y. Takekoshi (1990) ArticleTitleAcute tubulointerstitial nephritis with uveitis Arch Intern Med 150 688 Occurrence Handle10.1001/archinte.150.3.688a
A Gianviti M Greco P Barsotti G. Rizzoni (1994) ArticleTitleAcute tubulointerstitial nephritis occurring with 1-year lapse in identical twins Pediatr Nephrol 8 427–430 Occurrence Handle10.1007/BF00856521 Occurrence Handle7947032
Takemura T, Okada M, Hino S, Fukushima K, Yamamoto S, Miyazato H, Maruyama K, Yoshioka K. Course and outcomes of tubulointerstitial nephritis and uveitis syndrome. Am J Kidney Dis 1000; 34(1): 16–21
M Lessard J. Smith (1989) ArticleTitleFanconi syndrome with uveitis in an adult woman Am J Kidney Dis 13 158–159 Occurrence Handle2916570
U Gafter Y Kalechman D Zevin A Korzets E Livini T Klein B Stredni J. Levi (1993) ArticleTitleTubulointerstitial nephritis and uveitis: Association with suppressed cellular immunity Nephrol Dial Transplant 8 821–826 Occurrence Handle8255514
G Husby KS Tung RC Williams SuffixJr. (1981) ArticleTitleCharacterization of renal tissue lymphocytes in patients with interstitial nephritis Am J Med 70 31–38 Occurrence Handle10.1016/0002-9343(81)90408-3 Occurrence Handle7006393
J Rhodriguez-Perez M Cruz-Alamo P Perez-Aciego M Macia-Heras A Naranjo-Hernandez C Plaza-Toledano L Horatl-Cascon A. Fernandez-Rodriguez (1995) ArticleTitleClinical and immune aspects of idiopathic acute tubulointerstitial nephritis and uveitis syndrome Am J Nephrol 15 386–391 Occurrence Handle7503137
C Catalano PE Harris G Enia M Postorino C Martorano Q. Maggiore (1989) ArticleTitleAcute interstitial nephritis associated with uveitis and primary hypoparathyroidism Am J Kidney Dis 14 317–318 Occurrence Handle2801703
E Paul S Why Particlevan TO. Carpenter (1999) ArticleTitleHyperthyroidism: a novel feature of the tubulointerstitial nephritis and uveitis syndrome Pediatrics 104 314–317 Occurrence Handle10.1542/peds.104.2.314 Occurrence Handle10429017
H Wakaki H Sakamoto M. Awazu (2001) ArticleTitleTubulointerstitial nephritis and uveitis syndrome with autoantibody directed to renal tubular cells Pediatrics 107 1443–1446 Occurrence Handle10.1542/peds.107.6.1443 Occurrence Handle11389273
E O’Riordan RP Willert R Reeve PA Kalra DJ O’Donoghue RM Foley S. Waldek (2001) ArticleTitleIsolated sarcoid granulomatous interstitial nephritis: review of five cases at one center Clin Nephrol 55 297–302 Occurrence Handle11334315
A Gules S Masouridi AG Tzioufas JPA Ioannidis FN Skopouli HM. Moutsopoulos (2000) ArticleTitleClinically significant and biopsy-documented renal involvement in primary Sjogren syndrome Medicine (Baltimore) 79 241–249 Occurrence Handle10.1097/00005792-200007000-00005
K Hirano Y Tomino H Mikami K Ota Y Aikawa I Shirato H. Koide (1989) ArticleTitleA case of acute tubulointerstitial nephritis and uveitis syndrome with a dramatic response to corticosteroid therapy Am J Nephrol 9 499–503 Occurrence Handle2596540
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Helms, E., Servilla, K.S., Hartshorne, M.F. et al. Tubulointerstitial Nephritis and Uveitis Syndrome: Use of Gallium Scintigraphy in its Diagnosis and Treatment. Int Urol Nephrol 37, 119–122 (2005). https://doi.org/10.1007/s11255-004-2356-1
Issue Date:
DOI: https://doi.org/10.1007/s11255-004-2356-1