Skip to main content
Log in

Clinical, haematological and biochemical alterations in heat intolerance (panting) syndrome in Egyptian cattle following natural foot-and-mouth disease (FMD)

  • Original Research
  • Published:
Tropical Animal Health and Production Aims and scope Submit manuscript

Abstract

Clinical signs of heat intolerance (panting) syndrome were observed in Holstein cows in a private farm in Egypt. There were heat intolerance (fever), panting, profuse salivation, hirsutism, lameness and reduced milk production. Blood and serum samples were collected from ten diseased cows and five apparently healthy cows as control. Serological tests confirmed the presence of non-structural protein of foot-and-mouth disease (FMD) infection. There were significant reductions in the total red blood cell count with increased leucocytic and lymphocytic counts in diseased group compared to control. The serum Na, Cl, Ca, Mg, Zn and Fe were significantly reduced but P was increased in diseased animals compared to control. The total protein, albumin, cholesterol and cortisol were significantly reduced but the glucose and malonaldehyde were significantly increased in diseased cows. This was the first report in Egypt to describe the clinical and haemato-biochemical changes in panting syndrome following FMD.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

References

  • Akhtar, M.S., Farooq, A.A., and Mushtaq, M., 2009. Serum concentrations of copper, iron, zinc and selenium in cyclic and anoestrus Nili-Ravi buffaloes kept under farm conditions. Pakistan Veterinary Journal, 29(1), 47–48

    CAS  Google Scholar 

  • Altintaş, A., Şahal. S., Özkan Duru, S.C., and Öcal. N., 2001. Determination of serum and urine proteins by electrophoresis and its importance in clinical veterinary medicine. Turkish Journal of Veterinary and Animal Sciences, 25, 93–104

    Google Scholar 

  • Ansari-Lari, M., Nazifi, S., Rezaei, M. and Asadi-Fardaqi, J., 2008. Comparative study of plasma proteins including haptoglobin and serum amyloid A in different types of traumatic reticuloperitonitis in cattle. Comparative Clinical Pathology, 17, 245–249

    Article  CAS  Google Scholar 

  • Barasa, M., Catley, A., Machuchu, D., Laqua, H., Puot, E., Tap Kot, D., and Ikiror, D., 2008. Foot-and-mouth disease vaccination in South Sudan: benefit-cost analysis and livelihoods impact. Transboundry and Emerging Diseases, 55(8), 339–351

    Article  CAS  Google Scholar 

  • Barnett, P.V. and Cox, S.J., 1999. The role of small ruminants in the epidemiology and transmission of foot-and-mouth disease. Veterinary Journal, 158, 6–13

    Article  CAS  Google Scholar 

  • Benjamin, M.M., 1998. Haematology. In: Outline of Veterinary Clinical Pathology, 3rd edition. Kalyani publishers, New Delhi, 5–173

  • Bhattacharya, S., Banerjee, R., Ghosh, R., Chattopadhayay, A.P. and Chatterjee, A., 2005. Studies of the outbreaks of foot and mouth disease in West Bengal, India, between 1985 and 2002. Revue Scientifique et Technique/Office International des Epizooties, 24 (3), 945–952

    CAS  Google Scholar 

  • Breves, G., and Schroder, B., 1999. Calcium metabolism in ruminants—Physiological aspects and effect of anion rich diets. Proc. Soc. Nutr. Physiol., 8, 27–35

    Google Scholar 

  • Catley, A., Chibunda, R.T., Ranga, E., Makungu, S., Magayane, F.T., Magoma, G., Madege, M.J. and Vosloo, W., 2004. Participatory diagnosis of a heat-intolerance syndrome in cattle in Tanzania and association with foot-and-mouth disease. Preventive Veterinary Medicine, 65, 17–30

    Article  CAS  PubMed  Google Scholar 

  • Christensen, L.S., Okurut, R., Tjørnehøj, K., Normann, P., Soerensen, K.J. and Esau, M. Characterization of a new type O lineage of FMDV from Uganda with atypical clinical manifestations in domestic cattle (unpublished data).

  • Clark, Z., 2003. Diabetes mellitus in a 6-month-old Charolais heifer calf. Canadian Veterinary Journal, 44, 921–922

    Google Scholar 

  • Elitok, B., Balikci, E., Kececi, H. and Yilmaz, K., 1999. Sapl sigirlarda serum kreatinin fosfokinaz (CPK), laktat dehidrogenaz (LDH), aspartat aminotransferaz (AST), aktiviteleri, glikoz duzeyleri ve EKG bulgulari. Kafkas Univ. Vet. Fak. Derg., 5, 161–166

    Google Scholar 

  • Gokce, G., Gokce, H.I., Erdogan, H.M., Gunes, V. and Citil, M., 2004. Alterations in some haematological and biochemical parameters in cattle suffering from foot-and-mouth disease. Turkish Journal of Veterinary and Animal Science, 28, 723–727

    Google Scholar 

  • Gruenberg, W., Constable, P., Schröder, U., Staufenbiel, R., Morin, D. and Rohn, M., 2005. Phosphorus homeostasis in dairy cows with abomasal displacement or abomasal volvulus. Journal of Veterinary Internal Medicine, 19(6), 894–894

    Article  Google Scholar 

  • Grünwaldt, E.G., Guevara, J.C., Estévez, O.R., Vicente, A., Rousselle, H., Alcuten, N., Aguerregaray, D. and Stasi, C.R., 2005. Biochemical and haematological measurements in beef cattle in Mendoza plain rangelands (Argentina). Tropical Animal Health and Production, 37(6), 527–540

    Article  PubMed  Google Scholar 

  • Kaneko, J.J., Harvey, J.W. and Bruss, M.L., 1997. Clinical Biochemistry of Domestic Animals, 5th ed. Academic Press, California, USA. pp 661–668

  • Klein, J., Hussain, M., Ahmad, M., Afzal. M. and Alexandersen, S., 2008. Epidemiology of foot-and-mouth disease in Landhi Dairy Colony, Pakistan, the world largest Buffalo colony. Virology Journal, 5, 53

    Article  PubMed  Google Scholar 

  • Lee, J.Y., Lee, S.H., Kim, H.H., Ha, J.M., Lee, S.H. and Ha, B.J., 2004. The preventive inhibition of chondroition sulfate against the CC14-induced oxidative stress of subellular level. Archives of Pharmacal Research, 27 (3), 340–345

    Article  CAS  PubMed  Google Scholar 

  • Lotfollahzadeh, S., Mohri, M., Bahadori, ShR., Dezfouly, M.R. and Tajik, P., 2008. The relationship between normocytic hypochromic anaemia and iron concentration together with hepatic enzyme activities in cattle infected with Fasciola hepatica. Journal of Helminthology, 82(1), 85–88

    Article  CAS  PubMed  Google Scholar 

  • Lu, Z., Cao, Y., Guo, J., Qi, S., Li, D., Zhang, Q., Ma, J., Chang, H., Liu, Z., Liu, X. and Xie, Q., 2007. Development and validation of a 3ABC indirect ELISA for differentiation of foot-and-mouth disease virus infected from vaccinated animals. Veterinary Microbiology, 125 (1-2), 157–169

    Article  CAS  PubMed  Google Scholar 

  • Magoma, G., Samuel, S., Kondela, A., Madege, M. and Makungu, S., 2000. A preliminary clinical investigation of a condition known as luzwiga in the Lake Zone of Tanzania. In: Annual Scientific Conference of the Tanzania. Veterinary Association, Arusha.

    Google Scholar 

  • Meyer, R.F. and Knudsen, R.C., 2001. Foot-and-Mouth disease: a review of the virus and the symptoms. Journal of Environmental Health, 64 (4), 21–23

    CAS  PubMed  Google Scholar 

  • Mohapatra, A.P.K., Kundu, A.K., Bisoi, P.C. and Prusty, B.M., 2005. Haematological and biochemical changes in crossbred cattle affected with foot and mouth disease Indian Veterinary Journal, 82 (2), 141–144

    CAS  Google Scholar 

  • Nazifi, S., Saeb, M., Karimi, T., Ghanbari, S., 2005. Diurnal variation of serum biochemical parameters in the Iranian fat-tailed sheep. Comparative Clinical Pathology, 14, 1–4

    Article  CAS  Google Scholar 

  • Radostits, O.M., Gay, C.C., Hinchcliff, K.W. and Constable, P.D., 2007. Veterinary Medicine: A textbook of the diseases of cattle, horses, sheep, pigs and goats. 10th Ed., Elsevier Health Sciences, Philadelphia, PA, USA, pp. 1498–1506

  • Rodriguez, L.L. and Grubman, M.J., 2009. Foot and mouth disease virus vaccines. Vaccine, 27 (Suppl 4), 90–94

    Article  CAS  Google Scholar 

  • Roussel, A.J., Whitney, M.S. and Cole, D.J., 1997. Interpreting a bovine serum chemistry profile: Part 1. Veterinary Medicine, 92, 553–558

    Google Scholar 

  • Rufael, T., Catley, A., Bogale, A., Sahle, M. and Shiferaw, Y., 2008. Foot and mouth disease in the Borana pastoral system, southern Ethiopia and implications for livelihoods and international trade. Tropical Animal Health and Production, 40, 29–38

    Article  CAS  PubMed  Google Scholar 

  • Susca, F., Sangalli, L., Sgoifo Rossi, C.A., Biondi, P.A. and Dell’Orto, V., 2006. Determination of malonaldehyde in bovine plasma during the receiving period and effects of phytoderivative diet supplementation. Veterinary Research Communications, 30(1), 391–393

    Article  Google Scholar 

  • Stockham, S.L. and Scott, M.A., 2008. Fundamentals of Veterinary Clinical Pathology, 2nd ed., Blackwell Publishing, Ames, Iowa, pp714

    Google Scholar 

  • Sutmoller, P., Barteling S.S., Olascoaga, R.C., Sumption, K.J. 2003. Control and eradication of foot-and-mouth disease. Virus Research, 91, 101–144

    Article  CAS  PubMed  Google Scholar 

  • Thilsing, T., Larsen, T., Jorgensen, R.J. and Houe, H., 2007. The Effect of dietary calcium and phosphorus supplementation in zeolite A treated dry cows on periparturient calcium and phosphorus homeostasis. Journal of Veterinary Medicine A, 54, 82–91

    Article  CAS  Google Scholar 

  • Toerien, C.A., Puchala, R., McCann, J.P., Sahlu, T. and Goetsch, A.L., 1999. Goetsch adrenocortical response to ACTH in Angora and Spanish goat wethers. Journal of Animal Science, 77, 1558–1564

    CAS  PubMed  Google Scholar 

  • Weber, C., 1998. Cortisol's purpose. Medical Hypotheses, 51 (4), 289–291

    Article  CAS  PubMed  Google Scholar 

  • Yeotikar, P.V., Bapat, S.T., Bilolikar, S.C. and Kulkarni, S.S., 2003. Metabolic profile of healthy cattle and cattle affected by foot-and-mouth disease. Veterinary Record, 153(1), 19–20

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Mohamed M. Ghanem.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Ghanem, M.M., Abdel-Hamid, O.M. Clinical, haematological and biochemical alterations in heat intolerance (panting) syndrome in Egyptian cattle following natural foot-and-mouth disease (FMD). Trop Anim Health Prod 42, 1167–1173 (2010). https://doi.org/10.1007/s11250-010-9543-0

Download citation

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11250-010-9543-0

Keywords

Navigation