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Selective Catalytic Reductions of Amides and Nitriles to Amines

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Abstract

This personal account summarizes our recent developments of catalytic hydrosilylations and hydrogenations of carboxylic amides and nitriles to selectively give amines. Special focus is given to highly chemoselective iron- and zinc-catalyzed reductions of amides.

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Acknowledgements

This work has been funded by the State of Mecklenburg-Western Pomerania, the BMBF, the DFG (Leibniz-price). We thank Dr. W. Baumann, Dr. C. Fischer, S. Buchholz, S. Schareina, A. Kammer, A. Koch, S. Rossmeisl, and K. Mevius (all at the LIKAT) for their excellent technical and analytical support.

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Authors and Affiliations

  1. Leibniz-Institut für Katalyse an der Universität Rostock, Albert-Einstein-Str. 29a, 18059, Rostock, Germany

    Shoubhik Das, Shaolin Zhou, Daniele Addis, Stephan Enthaler, Kathrin Junge & Matthias Beller

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  1. Shoubhik Das
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  2. Shaolin Zhou
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  3. Daniele Addis
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  4. Stephan Enthaler
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  5. Kathrin Junge
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  6. Matthias Beller
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Correspondence to Matthias Beller.

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Das, S., Zhou, S., Addis, D. et al. Selective Catalytic Reductions of Amides and Nitriles to Amines. Top Catal 53, 979–984 (2010). https://doi.org/10.1007/s11244-010-9526-4

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