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An efficient polymer-supported copper(II) catalyst for the N-arylation reaction of N(H)-heterocycles with aryl halides as well as arylboronic acids

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Abstract

Immobilization of copper onto polystyrene provided a polymer-supported copper(II) catalyst, which was effective in cross-coupling reactions between N-containing substrates and arylboronic acids using methanol as a solvent in air under base-free conditions. This catalyst was also effective in N-arylation of imidazole with aryl halides in DMSO using K2CO3 as a base under nitrogen atmosphere. The catalyst was characterized by physico-chemical and spectroscopic techniques. The product N-arylimidazoles and N-arylbenzimidazoles were isolated in good to excellent yields. This copper catalyst was air stable and could be recycled with minimal loss of activity.

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Acknowledgments

We thank the Department of chemistry, University of Calcutta, for providing us the instrumental support. We gratefully acknowledge DST, New Delhi, for award of grant under its FIST program to the Department of Chemistry, University of Kalyani. SMI acknowledges the following agencies for funding: DST, CSIR, and UGC, New Delhi, India.

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Authors and Affiliations

  1. Department of Chemistry, University of Kalyani, Kalyani, Nadia, West Bengal, 741235, India

    Manirul Islam, Sanchita Mondal, Paramita Mondal, Anupam Singha Roy, Noor Salam, Sumantra Paul, Dildar Hossain & Manir Mobarok

  2. Department of Chemistry, B. S. College, S-24 PGS, Canning, West Bengal, India

    Kazi Tuhina

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  1. Manirul Islam
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  2. Sanchita Mondal
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  3. Paramita Mondal
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  4. Anupam Singha Roy
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  6. Noor Salam
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  7. Sumantra Paul
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  8. Dildar Hossain
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  9. Manir Mobarok
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Correspondence to Manirul Islam.

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Islam, M., Mondal, S., Mondal, P. et al. An efficient polymer-supported copper(II) catalyst for the N-arylation reaction of N(H)-heterocycles with aryl halides as well as arylboronic acids. Transition Met Chem 36, 447–458 (2011). https://doi.org/10.1007/s11243-011-9489-8

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  • DOI: https://doi.org/10.1007/s11243-011-9489-8

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