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Coagulation and fibrinolytic protein kinetics in cardiopulmonary bypass

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Abstract

The development of Cardiopulmonary Bypass (CPB) catopulted the field of cardiothoracic surgery into a new dimension—one that changed the lives of individuals with congenital and acquired heart disease worldwide. Despite its contributions, CPB has clear limitations and creates unique challenges for clinicians and patients alike, stemming from profound hemostatic pertubations and accompanying risk for bleeding and possibly thrombotic complications.

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Acknowledgments

The authors would like to acknowledge Amin Mahnam, Jo J Hunt, Matthew D Carney and the Duke University Writing Center for their assistance with manuscript preparation. Frederick Spencer, MD served as guest editor for the manuscript.

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Authors and Affiliations

  1. Duke Cardiovascular Thrombosis Center, Duke Clinical Research Institute, 2400 Pratt Street, Durham, NC, 27705, USA

    Maryam Yavari & Richard C. Becker

  2. Isfahan University of Medical Sciences, Isfahan, Iran

    Maryam Yavari

  3. Duke University School of Medicine, Durham, NC, USA

    Richard C. Becker

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  1. Maryam Yavari
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Yavari, M., Becker, R.C. Coagulation and fibrinolytic protein kinetics in cardiopulmonary bypass. J Thromb Thrombolysis 27, 95–104 (2009). https://doi.org/10.1007/s11239-007-0187-5

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