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Challenges in the treatment of patients with essential thrombocythemia and acute coronary syndrome

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Abstract

Essential thrombocythemia (ET) is an acquired clonal hematological stem-cell disorder that is characterized by a persistent increase in platelet count over 600,000/μl and elevated megakaryocyte levels in the bone marrow. Patients with ET are on the one hand at risk of thrombosis and on the other hand of hemorrhagic events especially in patients with very high platelet accounts. We report two illustrative cases with ET and acute coronary syndrome from our recent clinical experience illustrating the challenges in the antithrombotic treatment of these patients.

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Authors and Affiliations

  1. Department of Cardiology and Cardiovascular Disease, Otfried-Müller-Str. 10, Tuebingen, 72076, Germany

    Christina Doesch, Björn Krämer, Tobias Geisler, Andreas E. May & Meinrad Gawaz

  2. Institute of Pathology Koblenz, Koblenzerstr. 157a, Koblenz, 56073, Germany

    Stefan-Martin Kroeber

  3. Institute of Molecular Pathology, Liebermeisterstr. 8, Tuebingen, 72076, Germany

    Reinhard Kandolf

Authors
  1. Christina Doesch
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  2. Björn Krämer
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  3. Tobias Geisler
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  4. Andreas E. May
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  5. Stefan-Martin Kroeber
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  6. Reinhard Kandolf
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  7. Meinrad Gawaz
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Correspondence to Christina Doesch.

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Doesch, C., Krämer, B., Geisler, T. et al. Challenges in the treatment of patients with essential thrombocythemia and acute coronary syndrome. J Thromb Thrombolysis 25, 193–197 (2008). https://doi.org/10.1007/s11239-007-0082-0

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  • DOI: https://doi.org/10.1007/s11239-007-0082-0

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